The Australian Immunisation Handbook 10th Edition 2013

in a monodose vial with a pre-filled diluent syringe. Each 0.5 mL
reconstituted dose contains ≥10 3.0 cell culture infectious dose 50%
(CCID 50 ) of the Schwarz measles virus, ≥10 3.7 CCID 50 of the RIT 4385
mumps virus, and ≥10 3.0 CCID 50 of the Wistar RA 27/3 rubella virus;
lactose; neomycin; sorbitol; mannitol.
Quadrivalent measles-mumps-rubella-varicella (MMRV) vaccines
• Priorix-tetra – GlaxoSmithKline (live attenuated measles virus
[Schwarz strain], mumps virus [RIT 4385 strain, derived from the
Jeryl Lynn strain], rubella virus [Wistar RA 27/3 strain] and varicellazoster
virus [Oka strain]). Lyophilised pellet in a monodose vial with
a pre-filled diluent syringe. Each 0.5 mL reconstituted dose contains
≥103.0 CCID of the Schwarz measles virus, ≥10 50 4.4 CCID of the RIT
50
4385 mumps virus, ≥103.0 CCID of the Wistar RA 27/3 rubella virus,
50
and ≥103.3 plaque-forming units (PFU) of Oka varicella-zoster virus;
lactose; neomycin; sorbitol; mannitol.
• ProQuad – CSL Limited/Merck & Co Inc (live attenuated measles
virus [Enders’ attenuated Edmonston strain], mumps virus [Jeryl
Lynn B level strain], rubella virus [Wistar RA 27/3 strain] and
varicella-zoster virus [Oka/Merck strain]). Lyophilised powder
in a monodose vial with a pre-filled diluent syringe. Each 0.5 mL
reconstituted dose contains ≥10 3.0 TCID 50 of Enders’ attenuated
Edmonston measles virus, ≥10 4.3 TCID 50 of the Jeryl Lynn B level
mumps virus, ≥10 3.0 TCID 50 of the Wistar RA 27/3 rubella virus, and
≥10 3.99 PFU of Oka/Merck varicella virus; sucrose; hydrolysed gelatin;
urea; sorbitol; monosodium L-glutamate; human albumin; neomycin;
residual components of MRC-5 cells; bovine serum albumin.
4.9.5 Transport, storage and handling
Transport according to National vaccine storage guidelines: Strive for 5. 33 Store at
+2°C to +8°C. Do not freeze. Protect from light.
Both MMR and MMRV vaccines must be reconstituted by adding the entire
contents of the diluent container to the vial containing the pellet and shaking
until the pellet is completely dissolved.
Reconstituted Priorix (MMR), M-M-R II (MMR) and Priorix-tetra (MMRV)
vaccines should be used as soon as practicable. If storage is necessary, hold at
+2°C to +8°C for not more than 8 hours.
Reconstituted ProQuad (MMRV) vaccine must be used within 30 minutes.
270 The Australian Immunisation Handbook 10th edition