The Australian Immunisation Handbook 10th Edition 2013

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• MMR vaccine is to be used for the 1st dose at 12 months of age. MMRV is not recommended for use as the 1st dose of MMR-containing vaccine in children
• For Aboriginal and Torres Strait Islander children living in the Northern Territory, Queensland, South Australia or Western Australia, a booster dose of 13vPCV at 12–18 months of age replaces the booster dose of 23vPPV at 18–24 months of age. • The list of conditions associated with increased risks of invasive pneumococcal disease (IPD) (List 4.13.1) has been revised to include both adults and children, and is now divided into two categories: those conditions posing the highest increased risk of developing IPD and those associated with an increased risk of IPD. • The table (Table 4.13.3) summarising recommendations for vaccination of adults with 23vPPV has been revised. • Recommendations for the use of a single dose of 13vPCV in adults and children >5 years of age with conditions associated with the highest increased risk of IPD (and who have not previously received a 13vPCV dose) are included. • Information on the use of 23vPPV in persons >5 years of age at increased risk of IPD has also been more clearly presented. 4.14 Poliomyelitis • The 1st dose of IPV-containing combination vaccine due at 2 months of age can be given as early as 6 weeks of age. • A booster dose of IPV-containing vaccine is recommended at 4 years of age, but can be given as early as 3.5 years. 4.15 Q fever • Q fever vaccination and skin testing training is now undertaken via an educational module available online. • Information on the Australian Q Fever Register, which lists Q fever immunisation service providers and records of Q fever vaccinations given to some persons, is included. • Q fever vaccination is now also recommended for professional dog and cat breeders, and wildlife and zoo workers who have contact with at-risk animals, including kangaroos and bandicoots. 4.16 Rabies and other lyssaviruses (including Australian bat lyssavirus) • The terms PEP (post-exposure prophylaxis) and PreP (pre-exposure prophylaxis) are used throughout the chapter. • Information and recommendations on management of all potential lyssavirus exposures, including lyssavirus infection from exposure to bats in non-rabiesenzootic countries, is now included. • A 4-dose PEP schedule is now recommended for immunocompetent persons. A 5-dose schedule is only recommended for persons who are immunocompromised. PART 1 INTRODUCTION TO THE AUSTRALIAN IMMUNISATION HANDBOOK 15 1.4 WHAT'S NEW
Page 1 and 2: The Australian Immunisation Handboo
Page 3 and 4: FOREWORD Since 1932, when Governmen
Page 5 and 6: TABLE OF CONTENTS PART 1 INTRODUCTI
Page 7 and 8: LIST OF TABLES Table 2.1.1: Pre-vac
Page 9 and 10: List 4.13.1: Conditions associated
Page 11 and 12: PREFACE The 10th edition of The Aus
Page 13 and 14: Secretariat support, Australian Tec
Page 15 and 16: PART 1 INTRODUCTION TO THE AUSTRALI
Page 17 and 18: 1.2 DEVELOPMENT OF THE 10TH EDITION
Page 19 and 20: 1.3 HOW TO USE THE 10TH EDITION HAN
Page 21 and 22: 1.4 WHAT’S NEW All chapters have
Page 23 and 24: 2.2 Administration of vaccines •
Page 25 and 26: • The section on vaccination of p
Page 27: 4.6 Human papillomavirus • HPV va
Page 31 and 32: Part 5 Passive immunisation • Inf
Page 33 and 34: without the harmful consequences of
Page 35 and 36: (vaccine failure). Often such infec
Page 37 and 38: will occur following receipt of a s
Page 39 and 40: cases, both the doctor issuing the
Page 41 and 42: Should a child or adolescent refuse
Page 43 and 44: • check that the correct time int
Page 45 and 46: Note: Please discuss this informati
Page 47 and 48: Condition or circumstance of person
Page 49 and 50: Condition or circumstance of person
Page 51 and 52: Table 2.1.3: Live attenuated parent
Page 53 and 54: An online ‘catch-up calculator’
Page 55 and 56: Use of serological testing to guide
Page 57 and 58: • For some vaccines, catch-up vac
Page 59 and 60: Figure 2.1.1: Catch-up worksheet fo
Page 61 and 62: Vaccine Minimum age for 1st dose in
Page 63 and 64: Table 2.1.6: Number of vaccine dose
Page 65 and 66: Catch-up guidelines for individual
Page 67 and 68: If 13vPCV is not available, and 10v
Page 69 and 70: Previous vaccination history 2 prev
Page 71 and 72: PART 2 VACCINATION PROCEDURES 57 Ta
Page 73 and 74: PART 2 VACCINATION PROCEDURES 59 Ta
Page 75 and 76: Catch-up schedules for persons ≥1
Page 77 and 78: For additional details on these rec
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2.2 ADMINISTRATION OF VACCINES 2.2.
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• Never freeze a vaccine after it
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PART 2 VACCINATION PROCEDURES 69 In
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2.2.5 Vaccine injection techniques
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Interruption to a vaccination If th
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2.2.7 Positioning for vaccination I
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Children ≥12 months of age Cuddle
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2.2.8 Identifying the injection sit
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• Place the palm over the greater
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2.2.9 Administering multiple vaccin
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2.3 POST-VACCINATION 2.3.1 Immediat
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Management of an immediate adverse
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Management of anaphylaxis Rapid IM
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Autoinjectors are generally not app
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Australia. 16 This vaccine is no lo
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Any serious or unexpected adverse e
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Consumers and immunisation service
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When relevant, immunisation service
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National Human Papillomavirus Vacci
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Immunisation service providers enro
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PART 3 VACCINATION FOR SPECIAL RISK
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Thus, a vaccine to prevent Hib dise
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3.1.2 Adults Hepatitis B Indigenous
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een low in younger Indigenous adult
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3.2 VACCINATION FOR INTERNATIONAL T
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• vaccination history (including
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departure to allow for the period w
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Selected vaccines based on travel i
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Tick-borne encephalitis Tick-borne
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3.2.5 Vaccinating the traveller wit
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• Travel health and quarantine se
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whether the AEFI is likely to recur
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(see Appendix 1 Contact details for
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avoided, except in situations where
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3.3.3 Vaccination of immunocompromi
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Use of live viral or live bacterial
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Influenza vaccination is recommende
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Haematopoietic stem cell transplant
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Vaccine Months after HSCT Comments
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depending on the number of vaccines
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Persons with functional or anatomic
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Table 3.3.5: Recommendations for va
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Persons with autoimmune diseases an
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Table 3.3.6: Recommended intervals
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3.3.7 Vaccination of persons at occ
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Occupation Vaccine Providers of hom
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against certain vaccine-preventable
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3.3.11 Vaccination of persons who i
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waters. All cases of cholera report
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Children aged 2-6 years Three doses
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4.1.11 Adverse events The inactivat
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4.2.4 Vaccines Diphtheria toxoid is
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• Adacel - Sanofi Pasteur Pty Ltd
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antibodies at an age when waning of
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children aged
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4.3 HAEMOPHILUS INFLUENZAE TYPE B 4
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• Hiberix - GlaxoSmithKline (PRP-
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4.3.7 Recommendations Infants A Hib
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4.3.11 Public health management of
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In recent years, hepatitis A notifi
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Inactivated hepatitis A vaccines ar
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Co-administration with other vaccin
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Recommendations for the use of comb
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4.4.10 Adverse events The most comm
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4.5.3 Epidemiology The prevalence o
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4.5.4 Vaccines Monovalent hepatitis
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For older children and young adults
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Vaccine Age of vaccine recipient Do
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Combination hepatitis A/hepatitis B
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Management of infants born to mothe
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Household or other close (household
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with occult hepatitis B infection.
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immune memory persists and is thoug
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to suggest that a higher proportion
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Table 4.5.3: Post-exposure prophyla
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4.6 HUMAN PAPILLOMAVIRUS 4.6.1 Viro
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women. The prevalence of high-risk
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• Gardasil - CSL Limited/Merck &
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If scheduled doses have been missed
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However, some adult males may gain
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4.6.9 Contraindications The only ab
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4.7 INFLUENZA 4.7.1 Virology The in
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Figure 4.7.1: Influenza notificatio
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Always check annual seasonal influe
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7.5 µg of viral haemagglutinin (in
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Table 4.7.1: Recommended doses of i
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• Chronic respiratory conditions,
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Residents of residential aged care
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influenza vaccine prior to administ
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4.8 JAPANESE ENCEPHALITIS 4.8.1 Vir
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28 days following vaccination with
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When using JEspect in children aged
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4.8.8 Pregnancy and breastfeeding I
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4.9 MEASLES 4.9.1 Virology Measles
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4.9.4 Vaccines Monovalent measles v
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4.9.6 Dosage and administration The
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Table 4.9.1: Recommendations for me
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increase in adverse events from vac
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Immunoglobulin or blood product adm
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approximately 5%. 2,25 There is als
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Table 4.9.2: Post-exposure prophyla
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4.10 MENINGOCOCCAL DISEASE 4.10.1 B
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4.10.4 Vaccines There are different
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Polysaccharide vaccines Quadrivalen
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Interchangeability of meningococcal
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• Children (aged ≥9 months) and
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Appendix 1 Contact details for Aust
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4.11 MUMPS 4.11.1 Virology Mumps is
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Trivalent measles-mumps-rubella (MM
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4.11.7 Recommendations Infants aged
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Vaccination with other live attenua
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acquired from healthcare workers. 1
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demonstrated a more rapid decline,
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• Boostrix-IPV - GlaxoSmithKline
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in the previous 10 years. 19,45 Adu
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(see ‘Women who are planning preg
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an HHE. An HHE may last from a few
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The product information for Quadrac
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4.13 PNEUMOCOCCAL DISEASE 4.13.1 Ba
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non-Indigenous children (88%). 19,2
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10-valent pneumococcal conjugate va
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lesser antibody responses to 2nd or
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Table 4.13.1: Recommendations for p
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Category B: Conditions associated w
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Children aged >5 years to 15 years)
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Non-Indigenous adults A single dose
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Adults who have a condition listed
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4.13.11 Adverse events 10-valent pn
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5 years with a condition(s) associa
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virtually eradicated in India, but
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formaldehyde, glutaraldehyde, polys
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4.14.8 Pregnancy and breastfeeding
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4.15 Q FEVER 4.15.1 Bacteriology Q
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4.15.4 Vaccine • Q-Vax - CSL Limi
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individuals, which can be accessed
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Refer to 3.3 Groups with special va
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4.16 RABIES AND OTHER LYSSAVIRUSES
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4.16.4 Rabies vaccines • Mérieux
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of an even more accelerated schedul
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Pre-exposure prophylaxis for rabies
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The relevant state/territory health
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Although data are limited on the ef
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Table 4.16.2: Post-exposure prophyl
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Figure 4.16.2: Post-exposure prophy
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Figure 4.16.3: Booster algorithm fo
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allergic reaction occurs following
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age group11,12 and affecting 3.8% o
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of age, the risk of IS was increase
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Interchangeability of rotavirus vac
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gestational age; median 34 weeks) w
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Infants living in households with p
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4.17.12 Variations from product inf
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2003, rubella notifications in Aust
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zoster virus [Oka strain]). Lyophil
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children
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A number of commercial assays for t
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Germany indicates that no case of v
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case. Seronegative women of child-b
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4.19 TETANUS 4.19.1 Bacteriology Te
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Formulations for children aged
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4.19.5 Transport, storage and handl
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foreign bodies (especially wood spl
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studies indicate that the adverse r
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The product information for Adacel
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of MDR-TB cases identified has incr
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BCG vaccination procedures BCG vacc
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Occupational groups There is some e
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In developed countries, typhoid fev
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A 4th capsule taken on day 7 has be
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4.22 VARICELLA 4.22.1 Virology Vari
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as a case of wild-type varicella oc
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Reconstituted Varivax Refrigerated
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adequate protection from varicella.
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eceived varicella vaccine while bre
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immunoglobulin and other blood prod
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eported in a 9-year follow-up of 70
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high-dose intravenous NHIG are like
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4.23 YELLOW FEVER 4.23.1 Virology Y
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Co-administration with other vaccin
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Vaccine-associated neurotropic adve
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1000 cases per 100 000 population i
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administration of Zostavax with 23-
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diagnosis. In addition, the risk of
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Laboratory testing to check for an
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the immunoglobulin preparations con
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Prevention of measles Measles vacci
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who are being treated with immunosu
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limb with a separate syringe, and a
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APPENDIX 1: CONTACT DETAILS FOR AUS
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APPENDIX 2: LITERATURE SEARCH STRAT
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APPENDIX 3: COMPONENTS OF VACCINES
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Vaccine component* Vaccine brand
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APPENDIX 4: COMMONLY ASKED QUESTION
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When should preterm infants be vacc
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If a parent decides not to have a c
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Should vaccines be given to persons
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eason not to vaccinate. Asthma, ecz
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Does MMR vaccine cause inflammatory
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(either alone or in combination) fo
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A4.5 Questions about the need for i
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APPENDIX 5: GLOSSARY OF TECHNICAL T
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Enzootic enzootic infections are pr
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Rotavirus a virus that is a common
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APPENDIX 6: COMMONLY USED ABBREVIAT
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OPV oral poliomyelitis vaccine PCEC
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Year Vaccine 2003 Varicella 2003 Me
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identifying the injection site, 79-
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Australian Capital Territory advers
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and travellers, 119 vaccines, 177-1
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abies and other lyssaviruses (inclu
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HPV Vaccination Program, 234 human
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interferon-gamma release assays (IG
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mercury, in vaccines. see thiomersa
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Northern Territory ACIR reporting,
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and Haemophilus influenzae type b (
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espiratory syncytial virus monoclon
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Therapeutic Goods Administration (T
Page 537 and 538:
varicella-zoster immunoglobulin, 45
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INDEX 525 INDEX
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The Australian Immunisation Handbook 10th Edition 2013

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