The Australian Immunisation Handbook 10th Edition 2013

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• If the deltoid muscle mass is small: » give further injections into either anterolateral thigh (2.5 cm apart if two vaccines are given in the same thigh), or » give one injection into each ventrogluteal area. For younger children, the cuddle or straddle positions (Figures 2.2.3 and 2.2.4) are suitable for accessing multiple limbs during the one vaccination encounter. Simultaneous injections by two immunisation providers Currently there is insufficient evidence for or against having two immunisation providers administer vaccines at the same time rather than one vaccine after the other. 38,39 Two studies were unable to demonstrate a difference in pain response in the child between simultaneous administration and sequential administration. 38,39 If multiple immunisation providers are available, the technique has been explained to the parent and the parent gives consent, then the vaccines may be administered simultaneously, providing different sites can be safely accessed. References A full reference list is available on the electronic Handbook or website www.immunise.health.gov.au 84 The Australian Immunisation Handbook 10th edition
2.3 POST-VACCINATION 2.3.1 Immediate after-care Immediately after vaccine administration: • dispose of clinical waste, including sharps and vaccine vials, at the point of use (refer to state/territory health authorities for management guidelines for the safe disposal of clinical waste or refer to the National Health and Medical Research Council’s Australian guidelines for the prevention and control of infection in healthcare) 1 • cover the injection site quickly with a dry cotton ball and tape as needed • gently apply pressure for 1 or 2 minutes – do not rub the site as this will encourage the vaccine to leak back up the needle track, which can cause pain and may lead to local irritation • to distract the vaccinated person and reduce distress, immediately change the position of the child/person after completing the vaccination, for example, ask the parent/carer to put the infant over his/her shoulder and move around with the infant2 • remove the cotton wool after a few minutes and leave the injection site exposed to the air • record the relevant details of the vaccines given (see 2.3.3 Documentation of vaccination). The vaccinated person and/or parent/carer should be advised to remain in the vicinity for a minimum of 15 minutes after the vaccination. The area should be close enough to the immunisation service provider so that the vaccinated person can be observed and medical treatment provided rapidly if needed. Paracetamol is not routinely used before, or at the time of, vaccination, but may be recommended as required for fever or pain occurring following immunisation. Before departure, inform the vaccinated person or parent/carer, preferably in writing, of any expected adverse events following immunisation, and of the date of the next scheduled vaccination(s). Take the opportunity to check the vaccination status of other family members (as appropriate) and discuss any catch-up vaccination requirements and options available (this can also be done earlier in the visit). 2.3.2 Adverse events following immunisation What are adverse events following immunisation? An adverse event following immunisation (AEFI) is any untoward medical occurrence that follows immunisation and does not necessarily have a causal relationship with the usage of the vaccine. The adverse event may be any unfavourable or unintended sign, abnormal laboratory finding, symptom or disease. 3 Such an event may be caused by the vaccine(s) or may occur by chance PART 2 VACCINATION PROCEDURES 85 2.3 POST-VACCINATION
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The Australian Immunisation Handboo
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FOREWORD Since 1932, when Governmen
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TABLE OF CONTENTS PART 1 INTRODUCTI
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LIST OF TABLES Table 2.1.1: Pre-vac
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List 4.13.1: Conditions associated
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PREFACE The 10th edition of The Aus
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Secretariat support, Australian Tec
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PART 1 INTRODUCTION TO THE AUSTRALI
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1.2 DEVELOPMENT OF THE 10TH EDITION
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1.3 HOW TO USE THE 10TH EDITION HAN
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1.4 WHAT’S NEW All chapters have
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2.2 Administration of vaccines •
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• The section on vaccination of p
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4.6 Human papillomavirus • HPV va
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• For Aboriginal and Torres Strai
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Part 5 Passive immunisation • Inf
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without the harmful consequences of
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(vaccine failure). Often such infec
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will occur following receipt of a s
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cases, both the doctor issuing the
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Should a child or adolescent refuse
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• check that the correct time int
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Note: Please discuss this informati
Page 47 and 48: Condition or circumstance of person
Page 49 and 50: Condition or circumstance of person
Page 51 and 52: Table 2.1.3: Live attenuated parent
Page 53 and 54: An online ‘catch-up calculator’
Page 55 and 56: Use of serological testing to guide
Page 57 and 58: • For some vaccines, catch-up vac
Page 59 and 60: Figure 2.1.1: Catch-up worksheet fo
Page 61 and 62: Vaccine Minimum age for 1st dose in
Page 63 and 64: Table 2.1.6: Number of vaccine dose
Page 65 and 66: Catch-up guidelines for individual
Page 67 and 68: If 13vPCV is not available, and 10v
Page 69 and 70: Previous vaccination history 2 prev
Page 71 and 72: PART 2 VACCINATION PROCEDURES 57 Ta
Page 73 and 74: PART 2 VACCINATION PROCEDURES 59 Ta
Page 75 and 76: Catch-up schedules for persons ≥1
Page 77 and 78: For additional details on these rec
Page 79 and 80: 2.2 ADMINISTRATION OF VACCINES 2.2.
Page 81 and 82: • Never freeze a vaccine after it
Page 83 and 84: PART 2 VACCINATION PROCEDURES 69 In
Page 85 and 86: 2.2.5 Vaccine injection techniques
Page 87 and 88: Interruption to a vaccination If th
Page 89 and 90: 2.2.7 Positioning for vaccination I
Page 91 and 92: Children ≥12 months of age Cuddle
Page 93 and 94: 2.2.8 Identifying the injection sit
Page 95 and 96: • Place the palm over the greater
Page 97: 2.2.9 Administering multiple vaccin
Page 101 and 102: Management of an immediate adverse
Page 103 and 104: Management of anaphylaxis Rapid IM
Page 105 and 106: Autoinjectors are generally not app
Page 107 and 108: Australia. 16 This vaccine is no lo
Page 109 and 110: Any serious or unexpected adverse e
Page 111 and 112: Consumers and immunisation service
Page 113 and 114: When relevant, immunisation service
Page 115 and 116: National Human Papillomavirus Vacci
Page 117 and 118: Immunisation service providers enro
Page 119 and 120: PART 3 VACCINATION FOR SPECIAL RISK
Page 121 and 122: Thus, a vaccine to prevent Hib dise
Page 123 and 124: 3.1.2 Adults Hepatitis B Indigenous
Page 125 and 126: een low in younger Indigenous adult
Page 127 and 128: 3.2 VACCINATION FOR INTERNATIONAL T
Page 129 and 130: • vaccination history (including
Page 131 and 132: departure to allow for the period w
Page 133 and 134: Selected vaccines based on travel i
Page 135 and 136: Tick-borne encephalitis Tick-borne
Page 141 and 142: 3.2.5 Vaccinating the traveller wit
Page 143 and 144: • Travel health and quarantine se
Page 145 and 146: whether the AEFI is likely to recur
Page 147 and 148: (see Appendix 1 Contact details for
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PART 3 VACCINATION FOR SPECIAL RISK
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avoided, except in situations where
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3.3.3 Vaccination of immunocompromi
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Use of live viral or live bacterial
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Influenza vaccination is recommende
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Haematopoietic stem cell transplant
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Vaccine Months after HSCT Comments
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depending on the number of vaccines
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Persons with functional or anatomic
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Table 3.3.5: Recommendations for va
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Persons with autoimmune diseases an
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Table 3.3.6: Recommended intervals
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3.3.7 Vaccination of persons at occ
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Occupation Vaccine Providers of hom
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against certain vaccine-preventable
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3.3.11 Vaccination of persons who i
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waters. All cases of cholera report
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Children aged 2-6 years Three doses
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4.1.11 Adverse events The inactivat
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4.2.4 Vaccines Diphtheria toxoid is
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• Adacel - Sanofi Pasteur Pty Ltd
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antibodies at an age when waning of
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children aged
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4.3 HAEMOPHILUS INFLUENZAE TYPE B 4
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• Hiberix - GlaxoSmithKline (PRP-
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4.3.7 Recommendations Infants A Hib
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4.3.11 Public health management of
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In recent years, hepatitis A notifi
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Inactivated hepatitis A vaccines ar
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Co-administration with other vaccin
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Recommendations for the use of comb
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4.4.10 Adverse events The most comm
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4.5.3 Epidemiology The prevalence o
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4.5.4 Vaccines Monovalent hepatitis
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For older children and young adults
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Vaccine Age of vaccine recipient Do
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Combination hepatitis A/hepatitis B
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Management of infants born to mothe
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Household or other close (household
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with occult hepatitis B infection.
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immune memory persists and is thoug
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to suggest that a higher proportion
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Table 4.5.3: Post-exposure prophyla
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4.6 HUMAN PAPILLOMAVIRUS 4.6.1 Viro
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women. The prevalence of high-risk
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• Gardasil - CSL Limited/Merck &
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If scheduled doses have been missed
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However, some adult males may gain
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4.6.9 Contraindications The only ab
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4.7 INFLUENZA 4.7.1 Virology The in
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Figure 4.7.1: Influenza notificatio
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Always check annual seasonal influe
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7.5 µg of viral haemagglutinin (in
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Table 4.7.1: Recommended doses of i
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• Chronic respiratory conditions,
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Residents of residential aged care
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influenza vaccine prior to administ
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4.8 JAPANESE ENCEPHALITIS 4.8.1 Vir
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28 days following vaccination with
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When using JEspect in children aged
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4.8.8 Pregnancy and breastfeeding I
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4.9 MEASLES 4.9.1 Virology Measles
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4.9.4 Vaccines Monovalent measles v
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4.9.6 Dosage and administration The
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Table 4.9.1: Recommendations for me
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increase in adverse events from vac
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Immunoglobulin or blood product adm
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approximately 5%. 2,25 There is als
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Table 4.9.2: Post-exposure prophyla
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4.10 MENINGOCOCCAL DISEASE 4.10.1 B
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4.10.4 Vaccines There are different
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Polysaccharide vaccines Quadrivalen
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Interchangeability of meningococcal
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• Children (aged ≥9 months) and
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Appendix 1 Contact details for Aust
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4.11 MUMPS 4.11.1 Virology Mumps is
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Trivalent measles-mumps-rubella (MM
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4.11.7 Recommendations Infants aged
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Vaccination with other live attenua
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acquired from healthcare workers. 1
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demonstrated a more rapid decline,
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• Boostrix-IPV - GlaxoSmithKline
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in the previous 10 years. 19,45 Adu
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(see ‘Women who are planning preg
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an HHE. An HHE may last from a few
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The product information for Quadrac
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4.13 PNEUMOCOCCAL DISEASE 4.13.1 Ba
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non-Indigenous children (88%). 19,2
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10-valent pneumococcal conjugate va
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lesser antibody responses to 2nd or
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Table 4.13.1: Recommendations for p
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Category B: Conditions associated w
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Children aged >5 years to 15 years)
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Non-Indigenous adults A single dose
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Adults who have a condition listed
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4.13.11 Adverse events 10-valent pn
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5 years with a condition(s) associa
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virtually eradicated in India, but
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formaldehyde, glutaraldehyde, polys
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4.14.8 Pregnancy and breastfeeding
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4.15 Q FEVER 4.15.1 Bacteriology Q
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4.15.4 Vaccine • Q-Vax - CSL Limi
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individuals, which can be accessed
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Refer to 3.3 Groups with special va
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4.16 RABIES AND OTHER LYSSAVIRUSES
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4.16.4 Rabies vaccines • Mérieux
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of an even more accelerated schedul
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Pre-exposure prophylaxis for rabies
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The relevant state/territory health
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Although data are limited on the ef
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Table 4.16.2: Post-exposure prophyl
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Figure 4.16.2: Post-exposure prophy
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Figure 4.16.3: Booster algorithm fo
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allergic reaction occurs following
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age group11,12 and affecting 3.8% o
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of age, the risk of IS was increase
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Interchangeability of rotavirus vac
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gestational age; median 34 weeks) w
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Infants living in households with p
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4.17.12 Variations from product inf
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2003, rubella notifications in Aust
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zoster virus [Oka strain]). Lyophil
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children
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A number of commercial assays for t
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Germany indicates that no case of v
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case. Seronegative women of child-b
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4.19 TETANUS 4.19.1 Bacteriology Te
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Formulations for children aged
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4.19.5 Transport, storage and handl
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foreign bodies (especially wood spl
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studies indicate that the adverse r
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The product information for Adacel
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of MDR-TB cases identified has incr
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BCG vaccination procedures BCG vacc
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Occupational groups There is some e
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In developed countries, typhoid fev
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A 4th capsule taken on day 7 has be
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4.22 VARICELLA 4.22.1 Virology Vari
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as a case of wild-type varicella oc
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Reconstituted Varivax Refrigerated
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adequate protection from varicella.
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eceived varicella vaccine while bre
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immunoglobulin and other blood prod
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eported in a 9-year follow-up of 70
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high-dose intravenous NHIG are like
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4.23 YELLOW FEVER 4.23.1 Virology Y
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Co-administration with other vaccin
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Vaccine-associated neurotropic adve
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1000 cases per 100 000 population i
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administration of Zostavax with 23-
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diagnosis. In addition, the risk of
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Laboratory testing to check for an
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the immunoglobulin preparations con
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Prevention of measles Measles vacci
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who are being treated with immunosu
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limb with a separate syringe, and a
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APPENDIX 1: CONTACT DETAILS FOR AUS
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APPENDIX 2: LITERATURE SEARCH STRAT
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APPENDIX 3: COMPONENTS OF VACCINES
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Vaccine component* Vaccine brand
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APPENDIX 4: COMMONLY ASKED QUESTION
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When should preterm infants be vacc
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If a parent decides not to have a c
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Should vaccines be given to persons
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eason not to vaccinate. Asthma, ecz
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Does MMR vaccine cause inflammatory
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(either alone or in combination) fo
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A4.5 Questions about the need for i
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APPENDIX 5: GLOSSARY OF TECHNICAL T
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Enzootic enzootic infections are pr
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Rotavirus a virus that is a common
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APPENDIX 6: COMMONLY USED ABBREVIAT
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OPV oral poliomyelitis vaccine PCEC
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Year Vaccine 2003 Varicella 2003 Me
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identifying the injection site, 79-
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Australian Capital Territory advers
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and travellers, 119 vaccines, 177-1
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abies and other lyssaviruses (inclu
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HPV Vaccination Program, 234 human
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interferon-gamma release assays (IG
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mercury, in vaccines. see thiomersa
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Northern Territory ACIR reporting,
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and Haemophilus influenzae type b (
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espiratory syncytial virus monoclon
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Therapeutic Goods Administration (T
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varicella-zoster immunoglobulin, 45
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INDEX 525 INDEX
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The Australian Immunisation Handbook 10th Edition 2013

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