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The Australian Immunisation Handbook 10th Edition 2013

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When using JEspect in children aged ≥3 years and adults, primary vaccination<br />

consists of 2 doses, each of 0.5 mL, according to the following schedule:<br />

• 1st dose at day 0<br />

• 2nd dose 28 days after the 1st dose.<br />

Do not mix either Japanese encephalitis vaccine with any other vaccine in the<br />

same syringe.<br />

Co-administration with other vaccines<br />

Imojev can be given at the same time as the yellow fever vaccine, 24 using<br />

separate syringes and separate injection sites.<br />

Co-administration with other vaccines (including other live vaccines) has not<br />

been assessed. If Imojev and the yellow fever vaccine or other live vaccines are<br />

not given simultaneously, they should be given at least 4 weeks apart.<br />

JEspect can be co-administered with the hepatitis A vaccine. 25 Co-administration<br />

with other flavivirus vaccines (including yellow fever vaccine) has not been<br />

assessed.<br />

If co-administration of either JE vaccine with other vaccines is indicated,<br />

injections should be given in separate limbs.<br />

4.8.7 Recommendations<br />

<strong>The</strong> two available JE vaccines are registered for different age groups, and have<br />

different vaccination schedules, booster dose requirements, and contraindications<br />

for use. <strong>The</strong>se factors should be taken into account when deciding the most<br />

appropriate vaccine to use.<br />

<strong>The</strong> dose of Imojev should be administered at least 14 days prior to potential JE<br />

virus exposure.<br />

<strong>The</strong> JEspect vaccine (2-dose) schedule should be completed at least 1 week prior<br />

to potential JE virus exposure.<br />

Travellers<br />

JE vaccination is recommended for:<br />

• travellers (≥12 months of age) spending 1 month or more in rural areas of<br />

high-risk countries in Asia and Papua New Guinea (see 4.8.3 Epidemiology<br />

above); however, as JE has occurred in travellers after shorter periods of<br />

travel, JE vaccination should be considered for shorter-term travellers,<br />

particularly if the travel is during the wet season, or anticipated to be<br />

repeated, and/or there is considerable outdoor activity, and/or the<br />

accommodation is not mosquito-proof26 • all other travellers spending a year or more in Asia (except Singapore), even<br />

if much of the stay is in urban areas.<br />

PART 4 VACCINE-PREVENTABLE DISEASES 263<br />

4.8 JAPANESE ENCEPHALITIS

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