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The Australian Immunisation Handbook 10th Edition 2013

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influenza vaccine prior to administration is not recommended as there is poor<br />

correlation between test results and vaccine tolerance. 82,84-86<br />

However, there is still a low risk of anaphylaxis, so it is essential that such<br />

patients are vaccinated in facilities with staff able to recognise and treat<br />

anaphylaxis. Additional information on influenza vaccination of individuals<br />

with an allergy to eggs, including risk, dosage and observation period, can be<br />

found in the Australasian Society of Clinical Immunology and Allergy (ASCIA)<br />

guidelines. 84 (See also ‘Vaccination of persons with a known egg allergy’ in 3.3.1<br />

Vaccination of persons who have had an adverse event following immunisation.)<br />

Persons with a history of Guillain-Barré syndrome<br />

Persons with a history of Guillain-Barré syndrome (GBS) have an increased<br />

likelihood in general of developing GBS again, and the chance of them<br />

coincidentally developing the syndrome following influenza vaccination may be<br />

higher than in persons with no history of GBS. 87 Diagnosis of GBS is complex and<br />

must be made by a physician. (See also 4.7.11 Adverse events below.)<br />

Children requiring both influenza and 13-valent pneumococcal<br />

conjugate vaccine<br />

Parents/carers of infants or children who are recommended to receive both<br />

influenza vaccine and 13vPCV should be advised of the slightly higher risk<br />

of fever following concomitant administration of these vaccines (see 4.13<br />

Pneumococcal disease). Given this relatively low increase in risk, providing<br />

13vPCV and inactivated trivalent influenza vaccine concurrently to children aged<br />

12–23 months is acceptable; however, immunisation service providers should<br />

advise parents regarding this, and provide the option of administering these two<br />

vaccines on separate days (with an interval of not less than 3 days). In the event<br />

that fever occurs following either vaccine, an interval may minimise the risk of<br />

increased adverse reactions.<br />

4.7.11 Adverse events<br />

Fever, malaise and myalgia occur commonly, in 1 to 10% of persons who receive<br />

influenza vaccination. 88-90 <strong>The</strong>se adverse events may commence within a few<br />

hours of vaccination and may last for 1 to 2 days. 88-90 In children

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