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Urinalysis - The Carter Center

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21<br />

Test Procedure<br />

<strong>The</strong> test is conducted by smelling of urine and the result is based on the<br />

perception of the technician.<br />

Clinical Significance<br />

Abnormal urine odor may result from aging of urine, disease and diet.<br />

• If the urine specimen is old, i.e. after collection, left on the bench<br />

with out preservative for more than 2 hrs, it will have ammonical<br />

(pungent) odor. <strong>The</strong> ammonical odor result is due to break down and<br />

conversion of urea in the urine into ammonia by the action of<br />

bacteria.<br />

• Cystinuria and homocystinuria (type of amino acids, voided from<br />

abnormal metabolism) have sulfurous odor.<br />

• Oasthouse urine disease has a smell associated with the smell of a<br />

brewery (yeast).<br />

• Tyrosenemia is characterized by cabbage like or “fishy” urine odor.<br />

• <strong>The</strong> presence of ketone bodies in the urine, that may be due to<br />

diabetes mellitus, vomiting, starvation, strenuous exercise,<br />

characterized by “sweet fruity” odor.<br />

• Butyric / hexanoic acidemia produce a urine odor resembling that of<br />

sweat.<br />

• Urine of infants, which has inherited amino acid metabolism<br />

disorder, smells like “burnt sugar” or maple, hence the name, “maple<br />

sugar urine disease”.<br />

• Also due to some food stuff such as asparagus, characteristic, urine<br />

odor is produced, which has no clinical significance.<br />

3.2 Foam<br />

Normally when urine specimen is voided in a container, it produces small<br />

amount of white foam. But during certain abnormal physiological and

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