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Urinalysis - The Carter Center

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37<br />

CHAPTER FOUR<br />

Chemical Analysis Of Urine<br />

Introduction<br />

Chemical analysis of urine is an important procedure, which is<br />

impotant in the detection of many diseases. Urine contains normal<br />

chemical compositions. But in abnormal ( pathological ) conditions its<br />

composition varies in kind and quantities. So the chemical changes<br />

of urine can indicate disease at the early stage. <strong>The</strong> composition<br />

of urine varies because it is the principal route for soluble waste<br />

material from body metabolism. Its composiotion therefore depends<br />

greatly on how much and what specific waste material is to be<br />

excreted. Urea, creatinine, uric acid, ammonium salts, chlorides,<br />

sulphates and phosphates of sodium, potassium, calcium and<br />

magnesiumn are the normal composition of urine. <strong>The</strong>y are excreted<br />

through the urine as a final body metabolism. Glucose, protein,<br />

ketone bodies, bilirubin , bile salts etc. are the abnormal constituents<br />

of urine. Normaly these substances do not appear in the urine in<br />

detectable amount . So their appearance in the urine shows the<br />

pathological condition. For example, glucose does not appear in the<br />

urine in detectable amount . But during diabetes mellitus it appears in<br />

the urine. Protein also appears in the urine during renal disease.<br />

Generally the chemical examination of urine helps to investigate the<br />

health condition of individual.<br />

Objective:<br />

Give basic knowledge to the students on how to perform chemical tests<br />

and show the various types of method used to determine the chemical

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