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RRFM 2009 Transactions - European Nuclear Society

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estimate the gamma dose rate at the irradiation location were also performed using<br />

Landauer TLD-100 dosimeters.<br />

The incident gamma and neutron components were also measured using a set of FarWest TM<br />

paired ion chambers, in keeping with the recommendations of the International BNCT<br />

Dosimetry Exchange [7]. The gamma dose was measured at 2.26 cGy/min whereas the<br />

neutron dose was measured at 1.72 cGy/min.<br />

Final gamma and neutron dose rate measurements surrounding the facility were also<br />

performed while the BNCT facility was in various configurations at 10 MW operation. In the<br />

“sample load” configuration, a field of 0.25 mSv/hr gamma and 0.25 mSv/hr neutron exists<br />

inside the irradiation chamber. In “beam on,” there is a field of 0.45 mSv/hr neutron on the<br />

lid, a field of 0.50 mSv/hr gamma on the east shielding blocks, a field of 0.25 mSV/hr on the<br />

beam axis on the north shield block, and a field of 0.25 mSv/hr on the west side.<br />

VI. Conclusions and Future Work<br />

Parameter studies, design calculations and initial performance measurements have been<br />

completed for the new BNCT facility. These results indicate that a more than adequate<br />

thermal neutron beamline facility has been designed and constructed for BNCT cell and<br />

small-animal radiobiology studies at the MURR. Near future work will include small animal<br />

phantom dosimetery measurements using flux wires and the FarWest TM paired ion<br />

chambers. Animal phantoms, containing flux wires, will be placed in the beam and the<br />

neutron dose will be calculated by taking the ratio of the flux wire activity measured on the<br />

paired ion chambers with the flux wire activity measured in the phantom. Kerma factors will<br />

be applied to calculate the primary biological components of the non-specific neutron dose<br />

(hydrogen knock on damage n(H,H’)n’, n( 14 N,p) 14 C and hydrogen prompt gamma production)<br />

and the dose from the reaction with 10 B.<br />

VII. References<br />

[1] Hawthorne M.F. and Lee, M.W., 2003. A Critical Assessment of Boron Target<br />

Compounds for Boron Neutron Capture Therapy, Journal of Neuro Oncology 62:33-<br />

45.<br />

[2] Kim, Myong-Seop et al., 2007. Development and characteristics of the HANARO<br />

neutron irradiation facility for applications in the boron neutron capture therapy field,<br />

Phys. Med. Biol. 52:2553-2566.<br />

[3] Rhoades, WA, et al., 1993. TORT-DORT: Two and Three-Dimensional Discrete-<br />

Ordinates Transport, Radiation Shielding Information Center, Oak Ridge National<br />

Laboratory, CCC-543.<br />

[4] Breismeister, JF, 1999. ”MCNP – A General Monte Carlo N-Particle Transport Code,<br />

Version 4C, LA-13709-M, Los Alamos National Laboratory, USA.<br />

[5] Roussin, R.W., 1980. BUGLE-80 Coupled 47-Neutron, 20 Gamma-Ray P3 Cross<br />

Section Library, DLC-75, Radiation Shielding Information Center, Oak Ridge National<br />

Laboratory, USA.<br />

[6] Lee, Byung-Chul, 2007. Korea Atomic Energy Research Institute, Private<br />

communication.<br />

[7] Järvinen, H., and Voorbraak, W.P., 2003. Recommendations for the Dosimetry of<br />

Boron Neutron Capture Therapy, Report 21425/03 55339/C, NRG Petten, The<br />

Netherlands.<br />

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