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Status of medicinal and aromatic plants in - Inia

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WORKING GROUP ON MEDICINAL AND AROMATIC PLANTS: FIRST MEETING<br />

Medic<strong>in</strong>al <strong>and</strong> <strong>aromatic</strong> plant production <strong>in</strong> the United K<strong>in</strong>gdom<br />

Rosemary Cole<br />

National Herb Centre (NHC), Banbury, United K<strong>in</strong>gdom<br />

Natural solutions are <strong>in</strong>creas<strong>in</strong>gly be<strong>in</strong>g sought to agrochemical, pharmaceutical <strong>and</strong> food<br />

issues <strong>and</strong> the market for herb products is grow<strong>in</strong>g rapidly, putt<strong>in</strong>g an additional stra<strong>in</strong> on<br />

resources as many herb species are wild harvested. A report by Lange (1998) claimed that<br />

70-90% <strong>of</strong> herbal products imported <strong>in</strong>to Germany are wild harvested. Current production <strong>of</strong><br />

herbs <strong>in</strong> the UK occupies a relatively small area (ca. 4000 ha), mostly <strong>of</strong> cul<strong>in</strong>ary herbs. Herb<br />

companies still import large quanitites <strong>of</strong> herbs which could be grown <strong>and</strong> there is<br />

considerable potential for expansion to provide <strong>in</strong>dustrial raw materials. In order to realize this<br />

potential <strong>and</strong> thus meet the UK government's policy aim <strong>of</strong> encourag<strong>in</strong>g the development <strong>of</strong><br />

crops for <strong>in</strong>dustrial applications, a number <strong>of</strong> projects have been <strong>in</strong>itiated. But evidence <strong>of</strong><br />

the biological activity <strong>of</strong> these materials, the feasibility <strong>and</strong> economics <strong>of</strong> UK production <strong>of</strong><br />

these crops needs to be obta<strong>in</strong>ed.<br />

A number <strong>of</strong> factors have been shown to <strong>in</strong>fluence the yield <strong>and</strong> composition <strong>of</strong> essential<br />

oils <strong>and</strong> bioactives from herb crops. These <strong>in</strong>clude genetics (orig<strong>in</strong>, variation),<br />

morphogenesis (leaf position <strong>and</strong> age, harvest, flower<strong>in</strong>g), environment (temperature, day<br />

length <strong>and</strong> light <strong>in</strong>tensity) <strong>and</strong> f<strong>in</strong>ally agricultural practices (nutrition, irrigation,<br />

propagation, harvest<strong>in</strong>g <strong>and</strong> extraction). Selection <strong>of</strong> plant material <strong>and</strong> the optimization <strong>of</strong><br />

agricultural practices is vital for the production <strong>of</strong> high quality herbs, essential oils <strong>and</strong><br />

extracts. The need to know how the crop has been produced (traceability <strong>of</strong> raw materials) <strong>and</strong><br />

concern over the quality <strong>of</strong> imports (pesticides, heavy metals) suggests there is scope to supply<br />

extracted natural products from herbs grown <strong>in</strong> the UK to provide high quality raw materials<br />

for <strong>in</strong>dustry. There is potential to develop the UK herb <strong>in</strong>dustry, which encompasses a number<br />

<strong>of</strong> small- <strong>and</strong> medium-sized companies, if they meet the str<strong>in</strong>gent specifications, supply cha<strong>in</strong><br />

<strong>and</strong> quality requirements. It is possible to capitalize on this opportunity with a better<br />

knowledge <strong>of</strong> cultivar selection, how herbs can best be grown under UK conditions <strong>and</strong> by<br />

develop<strong>in</strong>g new techniques which may lead to safer <strong>and</strong> more efficient extraction <strong>of</strong> natural<br />

products.<br />

Below are three projects <strong>in</strong> which the National Herb Centre is <strong>in</strong>volved.<br />

The Rapfi project (Rosemary antioxidants for the pharmaceutical <strong>and</strong> food <strong>in</strong>dustries) is part <strong>of</strong><br />

the Competitive Industrial Materials from Non Food Crops (CIMNFC) programme <strong>and</strong> is a<br />

collaboration between the National Herb Centre (NHC), Department <strong>of</strong> Biology at the<br />

University <strong>of</strong> Read<strong>in</strong>g, Department <strong>of</strong> Sonochemistry at the University <strong>of</strong> Coventry,<br />

J.K. K<strong>in</strong>gs <strong>of</strong> Coggeshall (Seedsmen), Advanced Phytonics (Extraction), Langford Electronics<br />

(Ultrasonic equipment) <strong>and</strong> Checkmate (Audit trail). The project objectives are to select<br />

rosemary accessions for high antioxidant activity, enhance antioxidant activity through the<br />

use <strong>of</strong> elicitors, produce a predictive model relat<strong>in</strong>g antioxidant activity to UV radiation, to<br />

develop an affordable extraction process <strong>and</strong> produce an audit trail for the whole production<br />

process.<br />

Accessions <strong>of</strong> Rosmar<strong>in</strong>us <strong>of</strong>fic<strong>in</strong>alis were collected from throughout Europe. In total<br />

80 accessions have been trialed <strong>and</strong> analyzed at the National Herb Centre. Results have<br />

shown that antioxidant potential as measured by the free radical scaveng<strong>in</strong>g activity <strong>and</strong><br />

cha<strong>in</strong> propagation correlated with carnosic acid (r=0.82 <strong>and</strong> 0.53 respectively). Rosemary<br />

antioxidants also reduced production <strong>of</strong> "<strong>of</strong>f flavours" such as hexanal. Rosemary accessions<br />

were therefore selected for antioxidant activity by screen<strong>in</strong>g for carnosic acid concentration.<br />

Field trials (30 accessions <strong>and</strong> 6 replicates) had been planted September 1999 <strong>in</strong> three

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