Autism Studies and Related Medical Conditions, January 2009 - TACA

where autism was one of the disabilities are described. The characterization of
the maternal infection have been possible and the connection between congenital
CMV-infection and autism is discussed.
Publication Types:
Case Reports
PMID: 2163029 [PubMed - indexed for MEDLINE]
15: J Autism Dev Disord. 1984 Jun;14(2):183-9.
Autism and congenital cytomegalovirus.
Stubbs EG, Ash E, Williams CP.
Two cases of congenital cytomegalovirus infection associated with autism are
reported. The viral hypothesis of autism is discussed along with a brief review
of the literature. Suggestions are made for future research.
Publication Types:
Case Reports
PMID: 6086566 [PubMed - indexed for MEDLINE]
16: J Autism Dev Disord. 1983 Sep;13(3):249-53.
Autism in a child with congenital cytomegalovirus infection.
Markowitz PI.
A case is reported of early infantile autism associated with a congenital
cytomegalovirus infection. The diagnosis of autism is based on the child's
failure to develop good interpersonal relationships, poor eye contact, delayed
and deviant use of language, and her rote and nonthematic use of objects and
playthings. Resistance to change and self-stimulatory behavior were also present.
Onset was before 2 years of age. Congenital cytomegalovirus infection was
suggested by the presence of an antibody response to the virus, culture of the
virus from the urine, sensorineural hearing loss, and inflammatory damage to the
retina of the eye. Although over time improvement was noted, at last examination
at the age of 5 years her behavior is still markedly deviant. This and other
reported cases suggest that congenital viral infection may be an important cause
of infantile autism. It is hypothesized that an ability of the agent to establish
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