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Autism Studies and Related Medical Conditions, January 2009 - TACA

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Schwab JJ.<br />

Publication Types:<br />

Case Reports<br />

Review<br />

PMID: 6761074 [PubMed - indexed for MEDLINE]<br />

29: Med Hypotheses. 1984 Apr;13(4):399-405.<br />

Reptilian behavioural patterns in childhood autism.<br />

Thong YH.<br />

Childhood autism may be caused by damage to three phylogenetically distinct<br />

regions of the brain, or their major pathways <strong>and</strong> connections. Injury to the<br />

neocortex results in loss of language <strong>and</strong> cognitive function, while injury to the<br />

limbic cortex results in autistic withdrawal <strong>and</strong> abolition of play behaviour.<br />

Injury to the more primitive striatal complex, mammalian counterpart of the brain<br />

of reptiles, results in a bizarre <strong>and</strong> truncated form of stereotyped <strong>and</strong><br />

ritualistic behaviour. The causes of brain injury in childhood autism could be<br />

those common in the perinatal period including cerebral anoxia, haemorrhage,<br />

phenylketonuria, neurolipidoses , meningitis, toxoplasmosis, <strong>and</strong> congenital<br />

rubella. All these conditions have previously been shown to be associated with<br />

childhood autism.<br />

PMID: 6727722 [PubMed - indexed for MEDLINE]<br />

30: Curr Neurovasc Res. 2006 May;3(2):149-57.<br />

Autoantibodies associated with psychiatric disorders.<br />

Margutti P, Delunardo F, Ortona E.<br />

Dipartimento di Malattie Infettive, Parassitarie e Immunomediate, Istituto<br />

Superiore di Sanità, Rome, Italy. ortona@iss.it.<br />

Growing evidence suggests that autoantibodies to neuronal or endothelial targets<br />

in psychiatric disorders exist <strong>and</strong> may be pathogenic. This review describes <strong>and</strong><br />

discusses the possible role of autoantibodies related to the psychiatric<br />

manifestations in autoimmune diseases, autoantibodies related to the psychiatric<br />

disorders present in post-streptococcal diseases, celiac disease, chronic fatigue<br />

<strong>Autism</strong> <strong>Studies</strong> & <strong>Related</strong> <strong>Medical</strong> <strong>Conditions</strong> – <strong>TACA</strong> © Page 124

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