Autism Studies and Related Medical Conditions, January 2009 - TACA

doses: 0 %(control), 0.5% and 1.5%. The combination effects of CLA with vitamin ADE
or selenium also were investigated. CLA at 0.5% increased serum immunoglobulin A, G,
mesenteric lymph node (MHN) and gut luminal IgA (secretory IgA) levels. However,
1.5% CLA decreased SIgG slightly. CLA both alone and combined with vitamin ADE and
selenium did not affect serum IgE. The levels of immunoglobulin concentration in the
0.5% CLA group were higher than those in the 1.5% CLA group. The level of serum IgG
in 1.5% CLA combined with selenium was maintained at the same level as that of
control. It is considered that overdoses of CLA (1.5%) even depressed the production of
immunoglobulin but selenium and/or vitamin inhibited this activity to a certain extent.In
this study, dietary CLA increased immunoglobulin production in a dose-dependent
manner. Vitamin ADE and Selenium combined with CLA also increased the
immunoglobulin production response except serum IgE.
89. D'Souza RM, D'Souza R. Vitamin A for preventing secondary infections in children
with measles—a systematic review. J Trop Pediatr. 2002 48(2):72-7. PMID 12022432
90. D'Souza RM, D'Souza R. Vitamin A for treating measles in children. Cochrane
Database Syst Rev. 2002;(1):CD001479. PMID 11869601
"REVIEWER'S CONCLUSIONS: Although we did not find evidence that a single dose of
200,000 IU of vitamin A per day was associated with reduced mortality among children
with measles, there was evidence that the same dose given for two days was
associated with a reduced risk of overall mortality and pneumonia specific mortality.
The effect was greater in children under the age of two years."
91. Madhulika et al. Vitamin A supplementation in post-measles complications. J Trop
Pediatr. 1994 Oct;40(5):305-7. PMID 7807628.
The case fatality rate was 16 per cent in those who received VIT.A, while the same was
32 per cent in those who did not receive Vit.A (P < 0.02)."
92. Hussey GD, Klein M. Routine high-dose vitamin A therapy for children hospitalized
with measles. J Trop Pediatr. 1993 39(6):342-5. PMID 8133555
Measles is without specific therapy and remains important globally as a cause of
childhood death. In controlled studies, high-dose vitamin A therapy (Hi-VAT)—with
400,000 IU vitamin A--has been demonstrated to markedly reduce measles-associated
morbidity and mortality."
93. Butler JC et al. Measles severity and serum retinol (vitamin A) concentration among
children in the United States. Pediatrics. 1993 Jun;91(6):1176-81. PMID 8502524
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