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Autism Studies and Related Medical Conditions, January 2009 - TACA

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y lipopolysaccharide administration. These results indicate that orally<br />

administrated K1 suppressed inflammation in the rat.<br />

PMID: 16636460 [PubMed - indexed for MEDLINE]<br />

Olmez A, Yalcin S, Yurdakok K, Coskun T. Serum selenium levels in acute gastroenteritis<br />

of possible viral origin. J Trop Pediatr. 2004 Apr;50(2):78-81.<br />

Hacettepe University, Ihsan Doğramaci Children's Hospital, Department of<br />

Pediatric Neurology, Ankara, Turkey. dr_akgun@yahoo.com<br />

Selenium, as an essential micronutrient, is required for the proper functioning of<br />

the immune system <strong>and</strong> its deficiency affects the occurrence, virulence, or<br />

disease progression of some viral infections. We conducted a study to determine<br />

the serum selenium levels of children with acute gastroenteritis of possible viral<br />

origin <strong>and</strong> the effect of the serum selenium levels on the severity <strong>and</strong> the<br />

morbidity of the disease. The study was performed prospectively on 109 children<br />

aged 2-24 months with diarrhea of less than 8 days' duration admitted to the<br />

Diarrheal Disease Training <strong>and</strong> Treatment Unit. Blood samples were taken for<br />

selenium measurement on admission <strong>and</strong> 7-10 days after the end of the disease.<br />

Forty-three healthy children formed the control group. The mean serum selenium<br />

level on admission (62.41 +/- 13.06 microg/dl) was significantly lower than the<br />

mean of the second samples 7-10 days after the end of the diarrhea (81.73 +/-<br />

17.10 microg/dl). The mean of the control group was 74.36 +/- 10.75 microg/dl,<br />

which was lower than the mean of the second samples but higher than the first<br />

sample. The frequency of vomiting <strong>and</strong> purging on admission <strong>and</strong> at the control<br />

visit, duration of diarrhea on admission, total duration of diarrhea, dehydration,<br />

breastfeeding, sex of the patients, <strong>and</strong> severity score of the disease did not alter<br />

the serum selenium levels. No correlation was detected between serum selenium<br />

levels <strong>and</strong> the parameters above. Further studies about the changes in selenium<br />

status during infectious diseases <strong>and</strong> the effect of selenium status on related<br />

mortality <strong>and</strong> morbidity are required to determine if there is need for<br />

supplementation.<br />

PMID: 15088795 [PubMed - indexed for MEDLINE]<br />

Pangborn J, Baker SM. <strong>Autism</strong>: Effective Biomedical Treatments (Have We Done<br />

Everything We Can For This Child? Individuality In An Epidemic). San Diego: <strong>Autism</strong><br />

Research Institute; 2nd Edition Sept. 2005:232-235.<br />

<strong>Autism</strong> <strong>Studies</strong> & <strong>Related</strong> <strong>Medical</strong> <strong>Conditions</strong> – <strong>TACA</strong> © Page 210

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