Autism Studies and Related Medical Conditions, January 2009 - TACA

Hadjivassiliou M, Grunewald RA, Lawden M, Davies-Jones GA, Powell T,
Smith CM: Headache and CNS white matter abnormalities associated with gluten
sensitivity. Neurology 2001 Feb 13;56(3):385-8.
Abstract: Department of Clinical Neurology, The Royal HallamshireHospital,
Sheffield,UK. m.hadjivassiliou@sheffield.ac.uk
The authors describe 10 patients with gluten sensitivity and abnormal MRI. All
experienced episodic headache, six had unsteadiness, and four had gait ataxia. MRI
abnormalities varied from confluent areas of high signal throughout the white matter to
foci of high signal scattered in both hemispheres. Symptomatic response to gluten-free
diet was seen in nine patients.
Dubynin VA , Ivleva IuA, Malinovskaia IV, Kamenskii AA, Andreeva LA,
Alfeeva LIu, Miasoedov NF: Changes in beta-casomorphine-7 effect on behavior of
albino rat pups in postnatal development [Article in Russian]. Zh Vyssh Nerv Deiat Im I
P Pavlova 2001 May-Jun;51(3):386-9.
Abstract: Lomonosov State University, Institute of Molecular Genetics, Russian
Academy of Sciences, Moscow.
The analgetic effect of heptapeptide beta-casomorphine-7 in newborn albino rats (20
mg/kg, i.p.) was recorded already 14 days after birth in the "hot plate" test. The first
signs of a possible influence of the peptide on motor activity were observed only at the
age of 28 days. They are expressed in impairment of motor coordination and change in
locomotion level ("Opto-Varimex" test). The obtained evidence probably reflect the
processes of discrete maturation of different components of the opioid system of the rat
brain.
Furlano RI, Anthony A, Day R, Brown A, McGarvey L, Thomson MA, Davies SE,
Berelowitz M, Forbes A, Wakefield AJ, Walker-Smith JA, Murch SH: Colonic
CD8 and gamma delta T-cell infiltration with epithelial damage in children with autism. J
Pediatr. 2001 Mar;138(3):366-72.
University Department of Paediatric Gastroenterology, the Inflammatory Bowel Diseases
Study Group, Royal Free and University College School of Medicine, London, United
Kingdom.
OBJECTIVES: We have reported colitis with ileal lymphoid nodular hyperplasia (LNH) in
children with regressive autism. The aims of this study were to characterize this lesion
and determine whether LNH is specific for autism. METHODS: Ileo-colonoscopy was
performed in 21 consecutively evaluated children with autistic spectrum disorders and
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