09.09.2014 Views

Autism Studies and Related Medical Conditions, January 2009 - TACA

Autism Studies and Related Medical Conditions, January 2009 - TACA

Autism Studies and Related Medical Conditions, January 2009 - TACA

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

increased risks for neurodevelopmental disorders following additional doses of<br />

thimerosal... The following are [sic] a brief sampling of some of effects observed:"<br />

autism = 7.62 (95% Confidence Interval (CI) = 1.84-31.5)<br />

autism = 11.35 (95% CI = 2.70-47.76)<br />

specific disorders of sleep of non-organic origin = 4.98 (95% CI = 1.55-15.94)<br />

specific disorders of sleep of non-organic origin = 4.64 (95% CI = 1.12-19.25)<br />

phase-disruption of 24-hour sleep-wake cycle = 53.64 (95% CI = 3.23-892.10)<br />

somnambulism or night terrors = 5.76 (95% CI = 1.38-24.05)<br />

attention deficit without mention of hyperactivity = 6.38 (95% CI = 1.56-26.09)<br />

attention deficit with mention of hyperactivity = 8.29 (95% CI = 2.03-33.89)<br />

developmental speech or language disorder = 2.09 (95% CI = 1.08-4.03)<br />

other developmental speech or language delay = 2.32 (95% CI = 1.20-4.48)<br />

unspecified delay in development = 2.08 (95% CI = 1.03-4.19)<br />

[the above data] among children receiving > 25 micrograms ethylmercury from<br />

thimerosal at age 1 month in comparison to children receiving 0 micrograms of<br />

ethylmercury at age 1 month;<br />

attention deficit disorder = 2.88 (95% CI = 1.05-7.88) <strong>and</strong><br />

attention deficit disorder = 2.84 (95% CI = 1.03-7.85), <strong>and</strong><br />

coordination disorder = 18.26 (95% CI = 5.65-59.01)<br />

among children receiving > 75 micrograms of ethylmercury from thimerosal in<br />

comparison to children receiving < 12.5 microgram from thimerosal at age 3 months;<br />

<strong>and</strong><br />

autism = 2.15 (95% CI = 1.04-4.43) <strong>and</strong><br />

among children receiving increases of 7.5-10 micrograms of thimerosal over 1 month, in<br />

comparison to children receiving less than 5 micrograms of ethylmercury from<br />

thimerosal over 1 month [9-10].<br />

"Additionally, studies were conducted in 2000 by CDC to evaluate the dose-response<br />

effects of thimerosal on childhood neurodevelopmental disorders based upon evaluation<br />

of the VSD database [11]. It was found that there were statistically significant<br />

relationships between increasing exposures to thimerosal <strong>and</strong> the following<br />

outcomes, including:<br />

(1) for two months of age, an unspecified developmental delay, which has its own ICD-<br />

9 code.<br />

(2) Exposure at three months of age, Tics.<br />

(3) Exposure at six months of age, language <strong>and</strong> speech delays, which are two separate<br />

ICD-9 codes.<br />

(4) Exposure at one, three <strong>and</strong> six months of age, the entire category of<br />

<strong>Autism</strong> <strong>Studies</strong> & <strong>Related</strong> <strong>Medical</strong> <strong>Conditions</strong> – <strong>TACA</strong> © Page 308

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!