Autism Studies and Related Medical Conditions, January 2009 - TACA

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10a. House Subcommittee Hearing transcripts: Truth Revealed: New Scientific Discoveries Regarding Mercury in Medicine and Autism. September 08, 2004 http://reform.house.gov/WHR/Hearings/EventSingle.aspx?EventID=1311 10b. Testimony of Lyn Redwood, RN, MSN; President; Safeminds http://reform.house.gov/UploadedFiles/Testimony Redwood.pdf 10c. Analysis and critique of the CDC's handling of the thimerosal exposure assessment based on Vaccine Safety Datalink (VSD) information. Safeminds, 2003. http://www.momsonamissionforautism.org/index/VSD.SafeMinds.critique.pdf 10d. NoMercury.org – an information resource about thimerosal http://www.nomercury.org/ 11. Verstraeten T, Davis RL, DeStefano F et al. Safety of thimerosal-containing vaccines: a two-phased study of computerized health maintenance organization databases. Pediatrics. 2003 Nov;112(5):1039-48. Erratum in: Pediatrics. 2004 Jan;113(1):184. 12. Geier MR, Geier DA. Neurodevelopmental disorders after thimerosal-containing vaccines: a brief communication. Exp Biol Med 2003 228(6):660-4 PMID 12773696 "We were initially highly skeptical that differences in the concentrations of thimerosal in vaccines would have any effect on the incidence rate of neurodevelopmental disorders after childhood immunization. This study presents the first epidemiologic evidence, based upon tens of millions of doses of vaccine administered in the United States, that associates increasing thimerosal from vaccines with neurodevelopmental disorders." 13. Geier DA, Geier MR. An assessment of the impact of thimerosal on childhood neurodevelopmental disorders. Pediatr Rehabil. 2003 6(2):97-102 PMID 14534046 "The [thimerosal] dose-response curves showed increases in odds ratios of neurodevelopmental disorders from both the VAERS and US Department of Education data closely linearly correlated with increasing doses of mercury from thimerosalcontaining childhood vaccines and that for overall odds ratios statistical significance was achieved. Similar slopes and linear regression coefficients for autism odds ratios in VAERS and the US Department of Education data help to mutually validate each other." Autism Studies & Related Medical Conditions – TACA © Page 310
14. Geier DA, Geier MR. A comparative evaluation of the effects of MMR immunization and mercury doses from thimerosal-containing childhood vaccines on the population prevalence of autism. Med Sci Monit. 2004 Mar;10(3):PI33-9. Epub 2004 Mar 01. 15. Geier MR, Geier DA. Autism and thimerosal-containing vaccines: analysis of the Vaccine Adverse Events Reporting System (VAERS). IOM presentation, Feb 9, 2004. Slides: http://www.iom.edu/view.asp?id=18392 Audio: http://www.iom.edu/view.asp?id=19120 16. Geier & Geier. Parents' worries about thimerosal in vaccines are well founded! http://pediatrics.aappublications.org/cgi/eletters/112/6/1394 [An excellent summary & rebuttal of pro-thimerosal articles.] 17. Baskin DS et al. Thimerosal induces DNA breaks, caspase-3 activation, membrane damage, and cell death in cultured human neurons and fibroblasts. Toxicol Sci. 2003 Aug;74(2):361-8. Epub 2003 May 28. PMID: 12773768 18. David Baskin, M.D. Relation of Neurotoxic Effects of Thimerosal to Autism. IOM presentation, Feb 9, 2004. Audio only: http://www.iom.edu/view.asp?id=19124 19. Pichichero ME et al. Mercury concentrations and metabolism in infants receiving vaccines containing thiomersal: a descriptive study. Lancet. 2002 30;360(9347):1737- 41. PMID 12480426 "Interpretation: Administration of vaccines containing thiomersal does not seem to raise blood concentrations of mercury above safe values in infants." [But see cite 20] 20. Waly M et al. Activation of methionine synthase by insulin-like growth factor-1 and dopamine: a target for neurodevelopmental toxins and thimerosal. Mol Psychiatry. 2004 Apr;9(4):358-70. PMID: 14745455 "Our findings outline a novel growth factor signaling pathway that regulates MS activity and thereby modulates methylation reactions, including DNA methylation. The potent inhibition of this pathway by ethanol, lead, mercury [at nanomolar levels described by Pichichero et al), aluminum and thimerosal suggests that it may be an important target of neurodevelopmental toxins." 21. Richard C. Deth, Ph.D. Effects of Mercury on Methionine Synthase: Implications for Disordered Methylation in Autism Defeat Autism Now! 2003 Philadelphia Autism Studies & Related Medical Conditions – TACA © Page 311
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Autism Studies & Related Medical Co
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Values of free and total carnitine
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observation suggests that certain m
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with autism. These data suggest tha
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Markers rs2056202 and rs2292813 wer
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2- Autism and Gastrointestinal Infl
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than in nondisease controls (p
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Buie, T. M. (2005). "Gastroesophage
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control children and significant nu
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Horvath, K. and J. A. Perman (2002)
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components indicates a role of NFH
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patients with Crohn disease, one of
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analyzed by a registered pediatric
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oligonucleotide probes targeting pr
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would be effective in alleviating c
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demonstrate a focal CD8-dominated g
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Chlamydia pneumoniae and Streptococ
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vaccine (MCV), and once-exposed chi
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Wakefield, A. J., S. H. Murch, et a
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Walker SJ, Hepner K, Segal J, Krigs
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R, Maisawa S, Miki K. Guidelines fo
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approximately 73 and 37kDa in plasm
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Cook, E. H., Jr., B. D. Perry, et a
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evealed, that AAb level may serve a
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findings, which consisted of obstru
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angiography was performed in all fo
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matched non-autistic siblings had d
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Todd, R. D. and R. D. Ciaranello (1
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eaction was further confirmed by DO
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asic protein (MBP) and glial acidic
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exhibit higher than average levels
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Feasby, T., B. Banwell, et al. (200
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each group participated. Observatio
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Rossignol, D. A., L. W. Rossignol,
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Tsuru, T., M. Mori, et al. (2000).
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Anderson, M. P., B. S. Hooker, et a
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continue. The documented prevalence
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contributing factors may contribute
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Chauhan, V., A. Chauhan, et al. (20
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and folate-dependent methionine syn
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confirmed would indicate that autis
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differed significantly in the patie
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end products (AGE's) in autism brai
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cells in area 22 (p
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nutritional, and toxic status in au
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increase in autism in the last deca
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morphological, genetic and animal m
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Rossignol, D. A. (2007). "Hyperbari
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conditions have demonstrated improv
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not been investigated yet, several
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positively correlated in the autist
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abnormalities are present in brain,
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(tetrahydrobiopterin) were selected
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7 - Autism & Infection - 22 citatio
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micro-organisms. The faecal flora o
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Research Support, U.S. Gov't, P.H.S
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presentation of this syndrome among
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disorder. Yamashita Y, Fujimoto C,
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chronic infection may predispose to
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Streptococcus group A. Vojdani A, C
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provides a detailed analysis of a n
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PMID: 16897390 [PubMed - indexed fo
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syndrome and substance abuse, and a
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to contribute to metal-induced neur
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School of Medical Sciences, Tottori
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Review PMID: 16198633 [PubMed - ind
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diseases in humans. Zinc is redox-i
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Office of Vaccines Research and Rev
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into ferritin or heme. It is not ye
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9 - Dietary Intervention Studies -
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different peptidases resulting in a
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Mechanisms of non-IgE mediated adve
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Reichelt KL, Knivsberg AM.: Can the
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observations is the opioid-excess t
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Patients with gluten ataxia have an
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Hadjivassiliou M, Grunewald RA, Law
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Carroccio A, Montalto G, Custro N,
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Alberti A, Pirrone P, Elia M, Warin
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Thus, a number of milk protein frag
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Abstract: Institute ofPediatrics, L
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Abstract: Service de Psychopatholog
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times peer week) was effective in i
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Reichelt K.L., Knivsberg A.M., Lind
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terminal tetrapeptides into the lef
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Considerable clinical evidence sugg
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material of the P2 fractionation st
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Huebner FR, Lieberman KW, Rubino RP
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Four aspects of clinical evidence f
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Dohan FC: Wheat "consumption" and h
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from 24 children with autism from o
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matched control group. There was a
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administration on certain disorders
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Coleman M, Steinberg G, Tippett J,
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Dolske MC, Spollen J, McKay S, Lanc
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and myo-inositol (-13%) concentrati
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cobalamin. This was associated with
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(significantly lower ratio of SAM t
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Fifty-three controlled trials of th
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PMID: 6765503 [PubMed - indexed for
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Liebscher DH, Liebscher DE. About t
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from patients were examined at outs
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National College of Naturopathic Me
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OBJECTIVE: Ionic magnesium (Mg(2+))
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Pfeiffer CC, Braverman ER. Zinc, th
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evidence support a role for omega-3
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PMID: 1307234 [PubMed - indexed for
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scavenge reactive species, then the
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hyperactivity in patients with ADHD
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esponse to folate deprivation. Expr
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improvement may only become apparen
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Walsh WJ, Glab LB, Haakenson ML. Re
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use other internal or external stan
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In contrast, therapy with very high
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increased in affected children comp
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largely unknown, but genetic, envir
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Campbell DB, Sutcliffe JS, Ebert PJ
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OBJECTIVE: Etiologically unexplaine
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globulin and gamma globulins, IgA,
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Fallon J. Could one of the most wid
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Th1-like (IL-2, IFN-gamma) and Th2-
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Jyonouchi H, Geng L, Ruby A, Reddy
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that may be partly associated with
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Department of Neurology, University
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Mehler MF, Kessler JA. Cytokines in
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Niehus R, Lord C. Early medical his
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Pletnikov MV, Jones ML, Rubin SA, M
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Silva SC, Correia C, Fesel C, Barre
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Page 267 and 268: Vojdani A, Campbell AW, Anyanwu E,
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Page 271 and 272: mechanisms in children with autism.
Page 273 and 274: 12 - Environmental Toxicities (4 ci
Page 275 and 276: 13 - Thimerosal and Toxicity A comp
Page 277 and 278: PMID: 18364366 [PubMed - indexed fo
Page 279 and 280: Eye Contact Lens. 2007 Jul;33(4):19
Page 281 and 282: [Contact allergy to preservatives c
Page 283 and 284: Marn-Pernat A, Buturović-Ponikvar
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Page 295 and 296: Mutat Res. 1993 May;287(1):29-46. P
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Page 299 and 300: Effect of organic and inorganic mer
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Page 309: neurodevelopmental delays, which in
Page 313 and 314: 29. Boyd Haley, Ph.D. Reduced Level
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Page 323 and 324: in autistic children. In this curre
Page 325 and 326: 87. Semba RD. Vitamin A and immunit
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Page 345 and 346: 169a. Hadjivassiliou M et al. Does
Page 347 and 348: 174. Headache and CNS white matter
Page 349 and 350: histology is difficult to interpret
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Page 353 and 354: 199. Stubbs EG et al. Autism and co
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Page 357 and 358: patients with IBS. Since the fermen
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237. James Neubrander, M.D. -- Bioc
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significantly more frequent in pati
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aseline. Physicians reported qualit
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http://www.publichealthreports.org/
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No Trade Name Sanofi Pasteur, Ltd 0
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Influenza, live FluMist MedImmune V
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Calculating Aluminum in Vaccines He
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16 - How Much Money is Spent on Vac
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consumer information (promotion mat
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evidence to the mercury-vaccine-aut
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More from Verstraeten (Now working
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18 -Difference between Number of Va
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