Autism Studies and Related Medical Conditions, January 2009 - TACA

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Related Articles 126: Effect of the ophthalmic preservative thimerosal on rabbit and human corneal endothelium. Van Horn DL, Edelhauser HF, Prodanovich G, Eiferman R, Pederson HF. Invest Ophthalmol Vis Sci. 1977 Apr;16(4):273-80. PMID: 844986 [PubMed - indexed for MEDLINE] Related Articles 127: Purification of monolayer cell cultures of the endocrine pancreas. Braaten JT, Järlfors U, Smith DS, Mintz DH. Tissue Cell. 1975;7(4):747-62. PMID: 1239830 [PubMed - indexed for MEDLINE] Related Articles 128: The effect of formaldehyde on the toxicity and potency of pertussis vaccine. Gottshall RY, Nelson E, Angela F, Anderson G. Health Lab Sci. 1975 Jan;12(1):35-40. PMID: 1053237 [PubMed - indexed for MEDLINE] Related Articles 129: Tissue concentrations of mercury after chronic dosing of squirrel monkeys with thiomersal. Blair AMJN, Clark B, Clarke AJ, Wood P. Toxicology. 1975;3(2):171-6. PMID: 804725 [PubMed - indexed for MEDLINE] Feeding mice with diets containing mercury-contaminated fish flesh from French Guiana: a model for the mercurial intoxication of the Wayana Amerindians. Autism Studies & Related Medical Conditions – TACA © Page 304
Bourdineaud JP, Bellance N, Bénard G, Brèthes D, Fujimura M, Gonzalez P, Marighetto A, Maury-Brachet R, Mormède C, Pédron V, Philippin JN, Rossignol R, Rostène W, Sawada M, Laclau M. Université de Bordeaux 1-CNRS UMR 5805, Station Marine d'Arcachon, place du Docteur Peyneau, Arcachon, France. jp.bourdineaud@epoc.u-bordeaux1.fr BACKGROUND: In 2005, 84% of Wayana Amerindians living in the upper marshes of the Maroni River in French Guiana presented a hair mercury concentration exceeding the limit set up by the World Health Organization (10 microg/g). To determine whether this mercurial contamination was harmful, mice have been fed diets prepared by incorporation of mercurypolluted fish from French Guiana. METHODS: Four diets containing 0, 0.1, 1, and 7.5% fish flesh, representing 0, 5, 62, and 520 ng methylmercury per g, respectively, were given to four groups of mice for a month. The lowest fish regimen led to a mercurial contamination pressure of 1 ng mercury per day per g of body weight, which is precisely that affecting the Wayana Amerindians. RESULTS: The expression of several genes was modified with mercury intoxication in liver, kidneys, and hippocampus, even at the lowest tested fish regimen. A net genetic response could be observed for mercury concentrations accumulated within tissues as weak as 0.15 ppm in the liver, 1.4 ppm in the kidneys, and 0.4 ppm in the hippocampus. This last value is in the range of the mercury concentrations found in the brains of chronically exposed patients in the Minamata region or in brains from heavy fish consumers. Mitochondrial respiratory rates showed a 35-40% decrease in respiration for the three contaminated mice groups. In the muscles of mice fed the lightest fish-containing diet, cytochrome c oxidase activity was decreased to 45% of that of the control muscles. When mice behavior was assessed in a cross maze, those fed the lowest and mid-level fishcontaining diets developed higher anxiety state behaviors compared to mice fed with control diet. CONCLUSION: We conclude that a vegetarian diet containing as little as 0.1% of mercury-contaminated fish is able to trigger in mice, after only one month of exposure, disorders presenting all the hallmarks of mercurial contamination. PMID: 18959803 [PubMed - in process] Environ Health. 2008 Oct 29;7:53 Hepatitis B triple series vaccine and developmental disability in US children aged 1– 9 years Carolyn Gallagher* and Melody Goodman Graduate Program in Public Health, Stony Brook University Medical Center, Health Sciences Center, State University of New York at Stony Brook, Stony Brook, New York, USA (Final version received 14 November 2007) This study investigated the association between vaccination with the Hepatitis B triple series vaccine prior to 2000 and developmental disability in children aged 1– 9 years (n¼1824), proxied by parental report that their child receives early intervention or special education services (EIS). National Health and Nutrition Examination Survey 1999–2000 data were analyzed and adjusted for survey design by Taylor Linearization using SAS version 9.1 software, with SAS callable SUDAAN version 9.0.1. The odds of receiving EIS were approximately nine times as great for vaccinated boys (n¼46) as for unvaccinated boys (n¼7), after adjustment for confounders. This study found statistically significant Autism Studies & Related Medical Conditions – TACA © Page 305
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Autism Studies & Related Medical Co
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Values of free and total carnitine
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observation suggests that certain m
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with autism. These data suggest tha
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Markers rs2056202 and rs2292813 wer
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2- Autism and Gastrointestinal Infl
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than in nondisease controls (p
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Buie, T. M. (2005). "Gastroesophage
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control children and significant nu
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Horvath, K. and J. A. Perman (2002)
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components indicates a role of NFH
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patients with Crohn disease, one of
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analyzed by a registered pediatric
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oligonucleotide probes targeting pr
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would be effective in alleviating c
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demonstrate a focal CD8-dominated g
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Chlamydia pneumoniae and Streptococ
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vaccine (MCV), and once-exposed chi
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Wakefield, A. J., S. H. Murch, et a
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Walker SJ, Hepner K, Segal J, Krigs
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R, Maisawa S, Miki K. Guidelines fo
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approximately 73 and 37kDa in plasm
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Cook, E. H., Jr., B. D. Perry, et a
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evealed, that AAb level may serve a
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findings, which consisted of obstru
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angiography was performed in all fo
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matched non-autistic siblings had d
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Todd, R. D. and R. D. Ciaranello (1
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eaction was further confirmed by DO
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asic protein (MBP) and glial acidic
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exhibit higher than average levels
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Feasby, T., B. Banwell, et al. (200
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each group participated. Observatio
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Rossignol, D. A., L. W. Rossignol,
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Tsuru, T., M. Mori, et al. (2000).
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Anderson, M. P., B. S. Hooker, et a
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continue. The documented prevalence
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contributing factors may contribute
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Chauhan, V., A. Chauhan, et al. (20
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and folate-dependent methionine syn
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confirmed would indicate that autis
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differed significantly in the patie
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end products (AGE's) in autism brai
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cells in area 22 (p
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nutritional, and toxic status in au
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increase in autism in the last deca
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morphological, genetic and animal m
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Rossignol, D. A. (2007). "Hyperbari
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conditions have demonstrated improv
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not been investigated yet, several
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positively correlated in the autist
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abnormalities are present in brain,
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(tetrahydrobiopterin) were selected
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7 - Autism & Infection - 22 citatio
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micro-organisms. The faecal flora o
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Research Support, U.S. Gov't, P.H.S
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presentation of this syndrome among
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disorder. Yamashita Y, Fujimoto C,
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chronic infection may predispose to
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Streptococcus group A. Vojdani A, C
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provides a detailed analysis of a n
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PMID: 16897390 [PubMed - indexed fo
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syndrome and substance abuse, and a
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to contribute to metal-induced neur
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School of Medical Sciences, Tottori
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Review PMID: 16198633 [PubMed - ind
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diseases in humans. Zinc is redox-i
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Office of Vaccines Research and Rev
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into ferritin or heme. It is not ye
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9 - Dietary Intervention Studies -
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different peptidases resulting in a
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Mechanisms of non-IgE mediated adve
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Reichelt KL, Knivsberg AM.: Can the
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observations is the opioid-excess t
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Patients with gluten ataxia have an
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Hadjivassiliou M, Grunewald RA, Law
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Carroccio A, Montalto G, Custro N,
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Alberti A, Pirrone P, Elia M, Warin
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Thus, a number of milk protein frag
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Abstract: Institute ofPediatrics, L
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Abstract: Service de Psychopatholog
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times peer week) was effective in i
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Reichelt K.L., Knivsberg A.M., Lind
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terminal tetrapeptides into the lef
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Considerable clinical evidence sugg
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material of the P2 fractionation st
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Huebner FR, Lieberman KW, Rubino RP
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Four aspects of clinical evidence f
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Dohan FC: Wheat "consumption" and h
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from 24 children with autism from o
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matched control group. There was a
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administration on certain disorders
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Coleman M, Steinberg G, Tippett J,
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Dolske MC, Spollen J, McKay S, Lanc
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and myo-inositol (-13%) concentrati
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cobalamin. This was associated with
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(significantly lower ratio of SAM t
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Fifty-three controlled trials of th
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PMID: 6765503 [PubMed - indexed for
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Liebscher DH, Liebscher DE. About t
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from patients were examined at outs
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National College of Naturopathic Me
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OBJECTIVE: Ionic magnesium (Mg(2+))
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Pfeiffer CC, Braverman ER. Zinc, th
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evidence support a role for omega-3
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PMID: 1307234 [PubMed - indexed for
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scavenge reactive species, then the
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hyperactivity in patients with ADHD
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esponse to folate deprivation. Expr
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improvement may only become apparen
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Walsh WJ, Glab LB, Haakenson ML. Re
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use other internal or external stan
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In contrast, therapy with very high
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increased in affected children comp
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largely unknown, but genetic, envir
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Campbell DB, Sutcliffe JS, Ebert PJ
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OBJECTIVE: Etiologically unexplaine
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globulin and gamma globulins, IgA,
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Fallon J. Could one of the most wid
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Th1-like (IL-2, IFN-gamma) and Th2-
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Jyonouchi H, Geng L, Ruby A, Reddy
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that may be partly associated with
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Department of Neurology, University
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Mehler MF, Kessler JA. Cytokines in
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Page 259 and 260: cytokines were measured using speci
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Page 265 and 266: (DSM)-IV and the International Clas
Page 267 and 268: Vojdani A, Campbell AW, Anyanwu E,
Page 269 and 270: Warren RP, Cole P, Odell JD, Pingre
Page 271 and 272: mechanisms in children with autism.
Page 273 and 274: 12 - Environmental Toxicities (4 ci
Page 275 and 276: 13 - Thimerosal and Toxicity A comp
Page 277 and 278: PMID: 18364366 [PubMed - indexed fo
Page 279 and 280: Eye Contact Lens. 2007 Jul;33(4):19
Page 281 and 282: [Contact allergy to preservatives c
Page 283 and 284: Marn-Pernat A, Buturović-Ponikvar
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Page 295 and 296: Mutat Res. 1993 May;287(1):29-46. P
Page 297 and 298: Krug HF, Culig H. Mol Pharmacol. 19
Page 299 and 300: Effect of organic and inorganic mer
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Page 315 and 316: 40c. Iacono G et al. Intolerance of
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Page 319 and 320: "OBJECTIVE: Intestinal pathology, i
Page 321 and 322: 67. Jeff Bradstreet, M.D. A Case-co
Page 323 and 324: in autistic children. In this curre
Page 325 and 326: 87. Semba RD. Vitamin A and immunit
Page 327 and 328: "These results suggest that large o
Page 329 and 330: 94. Bluhm DP, Summers RS. Plasma vi
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Page 333 and 334: 108. Thony B et al. Tetrahydrobiopt
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Page 345 and 346: 169a. Hadjivassiliou M et al. Does
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Page 349 and 350: histology is difficult to interpret
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205. Gill HS, Guarner F. Probiotics
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patients with IBS. Since the fermen
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demonstrate that probiotics possess
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237. James Neubrander, M.D. -- Bioc
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significantly more frequent in pati
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aseline. Physicians reported qualit
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http://www.publichealthreports.org/
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No Trade Name Sanofi Pasteur, Ltd 0
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Influenza, live FluMist MedImmune V
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Calculating Aluminum in Vaccines He
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16 - How Much Money is Spent on Vac
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consumer information (promotion mat
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evidence to the mercury-vaccine-aut
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More from Verstraeten (Now working
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18 -Difference between Number of Va
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