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Abstracts - Association for Chemoreception Sciences

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#P253 POSTER SESSION V:<br />

CENTRAL OLFACTION; CHEMOSENSORY<br />

PSYCHOPHYSICS & CLINICAL STUDIES<br />

Intensity of Salt Taste and Hypertension<br />

Mary E. Fischer 1 , Karen J. Cruickshanks 1 , Alex Pinto 1 ,<br />

Barbara E. K. Klein 1 , Ronald Klein 1 , F. Javier Nieto 1 ,<br />

James S. Pankow 2 , Derek J. Snyder 3<br />

1<br />

University of Wisconsin Madison, WI, USA, 2 University of<br />

Minnesota Minneapolis, MN, USA, 3 Yale University New Haven,<br />

CT, USA<br />

Perceived intensity of the taste of salt and its’ relationship with<br />

hypertension was investigated in the Beaver Dam Offspring<br />

Study, a population-based cohort study of sensory loss and aging.<br />

Intensity of taste sensation was measured using filter paper disks<br />

and a generalized magnitude scale (gLMS) with a range of 0 to<br />

100. Study subjects were participants who provided in<strong>for</strong>mation<br />

on hypertension history and who used the full range of the gLMS<br />

in practice. Hypertension was defined as either a systolic pressure<br />

of >140 mmHg, a diastolic pressure of > 90 mmHg, or reported<br />

blood pressure medication use. Covariates included age, gender,<br />

education, smoking, and obesity (Body Mass Index >30.0 kg/m 2 ).<br />

There were 1753 study subjects (mean age=49.6, range=21-84<br />

years) of whom 662 (38%) were hypertensive. The unadjusted<br />

mean salt intensity score did not differ between hypertensives<br />

(mean=29.3, standard deviation(s.d.)=19.5) and normotensives<br />

(mean=29.2, s.d.=19.2). After adjustment <strong>for</strong> age and gender, the<br />

odds of hypertension in participants rating the intensity as very<br />

strong or greater (> 53) were not significantly higher than the<br />

odds in participants rating the intensity as less than moderate<br />

(

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