Abstracts - Association for Chemoreception Sciences

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P O S T E R S and its associations with basic demographic characteristics of this diverse population. Acknowledgements: The National Social Life, Health, and Aging Project Wave II (R37 AG030481), Gianinno Graduate Research Fund #P335 POSTER SESSION VII: OLFACTORY PSYCHOPHYSICS & CLINICAL STUDIES; CENTRAL OLFACTION Olfaction and Executive Function in the Beaver Dam Offspring Study Carla R. Schubert 1 , Karen J. Cruickshanks 1 , Guan-Hua Huang 2 , Barbara EK Klein 1 , Ronald Klein 1 , James S. Pankow 3 , David M. Nondahl 1 1 University of Wisconsin Madison, WI, USA, 2 National Chiao Tung University Hsinchu, Taiwan, 3 University of Minnesota Minneapolis, MN, USA Olfactory impairment is associated with the 5-year incidence of cognitive impairment in older adults but it is unknown if there is an association present in younger adults in a general population. The objective of the current study is to determine the association between olfaction and cognitive function in the Beaver Dam Offspring Study, a study of familial and birth cohort effects on aging senses. The San Diego Odor Identification Test was used to measure olfaction, and olfactory impairment was defined as correctly identifying fewer than 6 out of 8 odorants. The Trail Making Test (TMT) was used to assess cognitive (executive) function. The TMT score is the time in seconds(s) it takes to complete the tasks, drawing a line sequentially connecting randomly placed numbers (TMTA) and alternating numbers and letters (TMTB) correctly, with a longer time considered a poorer per<strong>for</strong>mance. There were 2837 participants, aged 21-84 years (mean age 49 years) with olfaction and TMT data; 3.8% had olfactory impairment. In preliminary analyses, adjusting <strong>for</strong> age and sex, TMTA and TMTB time were significantly longer among those with olfactory impairment versus those without impairment (TMTA = 35.9 s vs. 27.6 s; TMTB=83.7 s vs. 67.0 s; respectively, p
showed that N1/P2 latencies were longer and amplitudes were lower in older people (N1 384±98ms/-5.01±4.00uv, P2 568±95ms/6.53±3.62uv) compared with younger (N1 316±31ms/- 7.20±3.43uv, P2 472±66ms/ 8.72±3.09uv; P0.05 in both cases). In Experiment 2 we hypothesized that additional factor such as edibility of the odorant source may influence odor pleasantness during aging. Thirty young adults (age: 18-40) were compared to 30 old adults (age: 60-75). Participants were asked to give their hedonic ratings of the same 20 odorants and to estimate odor intensity, familiarity, edibility as well as to give a brief verbal description about the odor. Odor threshold and identification scores were also assessed. Results revealed that the correlation between pleasantness and edibility ratings was overall significantly greater in young adults vs. old adults (p
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AChemS Association for Chemorecepti
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AChemS Association for Chemorecepti
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We are pleased to announce that sev
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#1 GIVAUDAN LECTURE Normal and Canc
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and against delta ENaC is being pur
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#13 SYMPOSIUM - GENETICS OF HUMAN O
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#19 SYMPOSIUM - CILIA, SENSORY DYSF
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#26 PLATFORM PRESENTATIONS - POLAK
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esponse selectivity for both OSNs a
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elicit glucagon-like peptide-1 (GLP
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contrast, changing the concentratio
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of OBPs, we have systematically sup
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whereas mouse and joystick reaction
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POSTER PRESENTATIONS #P1 POSTER SES
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PROP strips and PROP solutions. PAV
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#P11 POSTER SESSION I: TASTE IMAGIN
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TGI. The present study investigated
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delivered in the scanner intra-oral
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a universal odor descriptor map. Ho
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acetate or ethyl butyrate v/v in mi
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#P54 POSTER SESSION II: OLFACTORY P
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hours later, the levels of prolifer
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extrusion from OSNs. We are charact
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anchor of ‘strongest sensation of
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cells within gustatory papillae, we
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excite menthol- and/or CA-sensitive
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gene, HMBS was used. All primers we
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oom, without time keeping devices,
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#P113 POSTER SESSION III: OLFACTORY
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decreasing of endogenous volatiles
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may serve to integrate central and
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esponse magnitudes. Inhibitions rea
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the second a non-specific cation ch
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saline. Some of the labeled ORNs sh
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#P166 POSTER SESSION IV: CHEMOSENSO
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pregnancy block. In order to unders
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Page 121 and 122: #P278 POSTER SESSION VI: PERIPHERAL
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Page 145 and 146: pleasantness 3)of mixtures (A,B), A
Page 151 and 152: Index Aarts, H - P328 Abe, K - P88,
Page 153 and 154: Haase, L - P3, P4, P29, P355 Haddad
Page 155 and 156: Murata, Y - P272 Murphy, C - P3, P4
Page 157 and 158: Veldhuizen, M - P7, P24, P25, P242,
Page 159 and 160: Registration 7:30 am to 1:00 pm, 6:
Page 161 and 162: See you next year! AChemS 33rd Annu
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Abstracts - Association for Chemoreception Sciences

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