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ANNUAL REPORT <strong>2018</strong><br />
275<br />
External Research projects Submitted<br />
Sl. No. Title of the Project Principle<br />
Investigator with<br />
Dept. Name<br />
1 A Study on the temporal Dr. K.L. Krishna<br />
alterations of tau and ApoE<br />
expression and their role on<br />
seizure development in animal<br />
models of sporadic Alzheimer’s<br />
disease<br />
2 Does paradoxical sleep<br />
deprivation precipitates<br />
brain insulin resistance and<br />
early vascular ageing? -A<br />
preclinical investigation on the<br />
beneficial effects of cyclic AMP<br />
specific PDE4 and dipeptidyl<br />
pepdidase-4 inhibitors.<br />
3 Evaluation of novel synthetic<br />
mutant-EGFR specific inhibitors<br />
for retarding the growth of<br />
Non-Small Cell Lung Carcinoma<br />
(NSCLC) in-vitro and in-vivo<br />
4 Profiling of Impurities on Drugs<br />
Used in Chronic Diseases<br />
5 Development of enantioselective<br />
assay and evaluation of<br />
pharmacokinetic and<br />
pharmacodynamic properties of<br />
some selected CNS depressant<br />
drugs by HPLC Technique<br />
6 Ab initio Structure based design<br />
and anti-cancer evaluation of<br />
novel modulators of Pirh2-p53<br />
protein-protein interactions<br />
7 Design, synthesis and evaluation<br />
of novel glitazones<br />
8 Intervention of nutraceutical<br />
formulation to combat adverse<br />
reaction and cachexia in Cancer<br />
patients.<br />
9 Therapeutic Investigation of<br />
Sirtuin Inhibitors in Experimental<br />
Animal Models of Vascular<br />
Dementia<br />
10 Therapeutic Evaluation of<br />
RAAS modulators in vasculitic<br />
Neuropathic Pain Models in Rats<br />
Dr. Saravana Babu<br />
Dr. S.N. Manjula<br />
Dr. Anandkumar<br />
Tengli<br />
Dr. B M Gurupadayya<br />
Dr. M N Purohit 32<br />
Dr. BR Prashantha<br />
Kumar<br />
Ms. Thejaswini<br />
Dr. K Mruthunjaya<br />
Submitted to Amount Duration of the<br />
Project<br />
DST SERB<br />
31/07/2017<br />
DST SERB<br />
31/07/2017<br />
DST SERB<br />
31/07/2017<br />
DST (SERB)<br />
31/07/2017<br />
DST (SERB)<br />
31/07/2017<br />
DST (SERB)<br />
31/07/2017<br />
DST-SERB<br />
31/07/2017<br />
DST-WOSB<br />
31/8/2017<br />
Rs.47.61<br />
Rs.36.98<br />
Rs.63.86<br />
Rs.49.01<br />
Rs.16.36<br />
Rs.30.50<br />
Rs.32.00<br />
Rs.20.00<br />
3 Years<br />
3 Years<br />
3 Years<br />
3 years<br />
3 years<br />
3 years<br />
3 years<br />
3 yrs<br />
Dr. Muthuraman A. K-FIST (L-II) Rs.32.19 02 years<br />
Dr. Muthuraman A.<br />
VGST grant under<br />
the scheme of<br />
SMYSR (Subject<br />
Area: PHARMACY<br />
Rs. 3.78<br />
02 years<br />
11 Evaluation of renoprotective<br />
potential of bixin and turmeric<br />
oil by in-vitro and in-vivo<br />
experimental model: the<br />
possible mechanism of action<br />
12 Share and Mentor Institutions<br />
(Margdarshan) -Under AICTE<br />
Scheme<br />
13 National Conference on<br />
Pharmacoepidemiology &<br />
Pharmacoeconomics<br />
14 Development of Enantioselective<br />
Assay and Evaluation of<br />
Pharmacokinetic Properties of<br />
Some Selected Chiral Drugs by<br />
HPLC Technique<br />
15 Evaluation of influence of<br />
some selected herbal antidiabetic<br />
formulation on second<br />
generation sulfonylurea’s<br />
anti-diabetic drugs: Herbal drug<br />
interaction study<br />
16 Establishment of high<br />
throughput Molecular Dynamics<br />
simulation and synthetic facility<br />
in the Pharmaceutical Chemistry<br />
PG Laboratory<br />
17 Hybrid Virtual-screening and<br />
high throughput Molecular<br />
Dynamics simulationbased<br />
design, synthesis<br />
and evaluation of novel Mtb<br />
decaprenylphosphoryl-D-ribose<br />
oxidase (DprE1) inhibitors as<br />
anti-tubercular agents<br />
18 Formulation design,<br />
development and in vitroin<br />
vivo evaluation of<br />
cyclodextrinnanosponges for<br />
augmented therapy ofvulvovaginal<br />
candidiasis<br />
19 Understanding the role of AT1<br />
<br />
on mitochondrial dynamics in<br />
Parkinson’s disease<br />
20 Combination of chitosan and<br />
epigallocatechin-3-gallate with<br />
Nano-fungal cellulose - in vitro<br />
and in vivo experiments towards<br />
therapy for neurodegenerative<br />
diseases<br />
Dr.K.L. Krishna VGST, K-Fist level 2 Rs.40.00 02 years<br />
Dr. M. Ramesh<br />
Department of<br />
Pharmacy Practice<br />
Dr. M. Ramesh<br />
Department of<br />
Pharmacy Practice<br />
Dr BM Gurupadayya<br />
Dept. of<br />
Pharmaceutical<br />
Chemistry<br />
Dr BM Gurupadayya<br />
Dept. of<br />
Pharmaceutical<br />
Chemistry<br />
Dr. GV Pujar Dept.<br />
of Pharmaceutical<br />
Chemistry<br />
Dr. GV Pujar<br />
Dr. P K Kulkarni<br />
Dr Meena, University<br />
of Saskatchewan,<br />
Canada &<br />
Collaborator: Dr<br />
Saravana Babu<br />
Dr Manivasagam,<br />
Dept of Biochemistry,<br />
Annamalai Universit,<br />
Chidambaram,<br />
tamilnadu<br />
Co-Principal<br />
Investigator: Dr<br />
Saravana Babu<br />
AICTE 28th Nov.<br />
2017<br />
AICTE 29th<br />
Nov.2017<br />
K-FIST-Level-II and<br />
submitted on 2nd<br />
Nov. 2017<br />
AICTE-Research<br />
Promotion<br />
Scheme (RPS) and<br />
submitted on 30th<br />
Nov. 2017<br />
28th<br />
November,2017<br />
MODROBS(AICTE)<br />
6th November,2017<br />
VGST, K-FIST-<br />
Level-II<br />
AICTE-RPS Nov.<br />
2017<br />
Parkinson Canada,<br />
Jan. <strong>2018</strong><br />
Department<br />
of Science &<br />
Technology, Got. Of<br />
India January <strong>2018</strong><br />
Rs.50.00<br />
3 Years<br />
Rs. 5.00 3 Days (13-15<br />
April <strong>2018</strong>)<br />
Rs.10.00<br />
Rs.25.00<br />
Rs.20.00<br />
Rs.20.00<br />
2 years<br />
3 years<br />
2 years<br />
2 years<br />
28.00 Lakhs 3 years<br />
$ 50,000.00<br />
(Appx. 26.00.00<br />
JSSCPM<br />
component:<br />
$10,000) Rs.<br />
5.20.00<br />
75.11 JSSCPM<br />
component:<br />
(12,00,000.00)<br />
01 year<br />
03 years
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