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ANNUAL REPORT <strong>2018</strong><br />
317<br />
6 Engineered Affibody conjugated<br />
oxalipatin nano particles for<br />
the management of colorectal<br />
cancer<br />
7 Virtual high throughput<br />
screening (vHTS), design,<br />
synthesis, in vitro/ in vivo<br />
evaluation and 3D-QSAR<br />
investigations of some novel<br />
-carboline and carbazole lead<br />
molecules as antineoplastic<br />
agents<br />
8 In Silico design, synthesis<br />
and evaluation of MurD<br />
and MurE Ligase inhibitors<br />
against Methicillin resistant<br />
staphylococcus aureus, funded<br />
9 Phase transition mediated<br />
targeting of thermo-sensitive<br />
polymer drug conjugates to<br />
human ovarian tumours<br />
10 The mechanism of action of<br />
certain Ayurvedic Medicianal<br />
plants on Alzhemer’s by<br />
Dipeptidyl peptidase – 4<br />
inhibition using herbs<br />
11 Fund for Improvement of<br />
Science and Technology<br />
Infrastruture (FIST)<br />
12 Neuroprotection by Nano<br />
allosteric potentiators of M1<br />
Muscarinic Acetyl Choline<br />
receptor for reversal learning<br />
management in Alzheimer’s<br />
Diseases<br />
13 Novel approach to treat prostate<br />
cancer: Combinatorial therapy to<br />
target hypoxia induced ER stress<br />
using HIF- I alpha and ER stress<br />
Inhibitors<br />
Dr. K. Gowthamarajan AICTE, New Delhi 5.00 3 Years<br />
Dr.MJN.Chandrasekar<br />
Dr Md Afzal Azam<br />
DR MJN Chandrasekar<br />
Dr. B. Duraiswamy<br />
AYUSH, New Delhi<br />
Dr K Elango DST FIST<br />
New Delhi<br />
DBT, Govt of India,<br />
New Delhi<br />
DST SERB New<br />
Delhi<br />
DBT-NE,Govt. of<br />
India, New Delhi<br />
47.66 3 Years<br />
42.59 3 Years<br />
28.33 (74.32) 3 Years<br />
25.66 3 Years 3 year<br />
84.00 3 Years 3 year<br />
Dr T K Praveen DBT, New Delhi 72.00 3 Years<br />
Dr. K Elango (Ms.<br />
Sandhya)<br />
14 Tribal research P R AnandVijayaKumar<br />
Latrobe University<br />
15 A Clinical Study on the effect<br />
of metabolic syndrome on<br />
cognition across different age<br />
groups using MMSE scale and<br />
C - reactive protein as predictive<br />
biomarker<br />
16 Effect of Interventional<br />
strategies on insulin resistance<br />
in prediabetes: An open label<br />
prospective multi centre study<br />
P R AnandVijayaKumar<br />
Latrobe University<br />
Dr. S Ponnusankar (Ms.<br />
MohsinaHyder)<br />
DST WoS New<br />
Delhi<br />
7.00 3 Years<br />
2.48 3 Years 3 year<br />
13.00 3 Years 3 year<br />
DST WoS Scheme 8.00 3 Years<br />
External Research Projects Submitted<br />
Sl.No Title of the Project Principle<br />
Investigator with<br />
Dept. Name<br />
1 A novel Artemisinin-Flavonoid<br />
loaded Nanodroplet as a<br />
combination therapy to<br />
overcome the resistance in the<br />
treatment of malaria caused by<br />
P-faiciparum<br />
2 Alteration of breast cancer cell<br />
metabolism by metformin- glut1<br />
inhibitor loaded pluronic micelles<br />
3 Evaluation of anticancer drug<br />
linked to the Novel peptide binds<br />
to breast cancer<br />
4 Therapeutic Potential of disatinib<br />
nanoparticles linked to the Novel<br />
peptide binds to breast cancer<br />
5 Intracellular targeting of Elastin<br />
like Polypeptide-Drug conjugates<br />
by Phase-structure trasition to<br />
solid tumors<br />
Dr.R. Sureshkumar Science and<br />
Engineering<br />
Research<br />
Board(SERB), New<br />
Delhi<br />
Dr. K.<br />
Gowthamarajan<br />
Dr. GNK Ganesh<br />
Dr. GNK Ganesh<br />
Dr. MJN.<br />
Chandrasekar<br />
Submitted to Amount Duration of the<br />
Project<br />
25.00 3 Years<br />
DST-WOSA 27.77 3 Years<br />
Nano Mission of<br />
the Department<br />
of Science and<br />
Technology,<br />
Government of<br />
India. New Delhi<br />
DBT, New Delhi,<br />
India<br />
Extra Mural<br />
Research Funding<br />
(Individual Centric)<br />
25.35 3 Years<br />
35.00 3 Years<br />
47.81 3 Years<br />
6 MODROBS Dr. S. Sankar AICTE, New Delhi 20.00 3 Years<br />
7 Herbal mediated action of<br />
Paraozonase I (PON-1)enzyme<br />
in Atherosclerosis to prevent<br />
cardiovascular disorders<br />
8 Evaluation of Nano structured<br />
lipid carriers of Dasatinib and<br />
Resveratrol in Parkinson’s<br />
animal models<br />
9 Intervention of LRRK2 kinase<br />
inhibitors with adjuvants on<br />
striatal dopamine levels in<br />
6-OHDA and MPTP models of<br />
Parkinson’s disease<br />
10 Adipocyte specific delivery<br />
of oral thiazolidinedione<br />
nanoparticles functionized<br />
with RGD and P3 peptides to<br />
reduce side effects and improve<br />
efficacy.<br />
11 Surface modified solid lipid<br />
nanoparticles based delivery of<br />
Thiazolidinedione’s to adipocytes<br />
to improve their therapeutic<br />
efficacy and reduce their off<br />
target side effects<br />
Dr. B Duraiswamy<br />
Dr. T.K. Praveen<br />
Dr R Vadivelan<br />
Dr R Vadivelan<br />
Dr. T. K. Praveen<br />
DST-SERB, New<br />
Delhi<br />
DST SERB (Extra<br />
Mural Research<br />
Funding (Individual<br />
Centric)<br />
DST SERB (Extra<br />
Mural Research<br />
Funding (Individual<br />
Centric)<br />
DST Technology<br />
Nanomission<br />
division under Nano<br />
Bioscheme<br />
26.86 3 Years<br />
51.47 3 Years<br />
56.62 3 Years<br />
45.00 3 Years<br />
Dr. T. K. Praveen DST, New Delhi 39.84 3 Years