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Business Potential for Agricultural Biotechnology - Asian Productivity ...

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The <strong>Business</strong> <strong>Potential</strong> of <strong>Agricultural</strong> <strong>Biotechnology</strong> in the Republic of China<br />

Biopesticide and Biofertilizer<br />

In applied microbiology, biopesticide and biofertilizer are the two hot items in agriculture.<br />

Because of environmental safety and ecology considerations, biological control of pests has been<br />

increasingly welcomed by both farmers and consumers. Research on biopesticides began early at<br />

public institutes and universities, and some important results have been obtained. The fungi of<br />

Trichoderma spp. have been used to control many pathogens, including Rhizoctonia solani,<br />

Sclerotium rolfsii, Sclerotinia sclerotiorum, and Pythium aphanidermatum. They also can reduce<br />

the damage caused by Botrytis cinerea, Pseuperonospora cubensis, Sclerotinia sclerotinia, and<br />

Sphaerotheca fusca and thus are valuable <strong>for</strong> protecting leaves. These well-studied biocontrol<br />

agents have become an ideal subject <strong>for</strong> commercialization. Other well-studied natural antifungal<br />

agents include Bacillus subtilis and Streptomyces. Further studies have shown how to<br />

make these natural resources easy to use in agricultural practices. The <strong>Agricultural</strong> Research<br />

Institute (ARI) has undertaken significant ef<strong>for</strong>ts in the commercialization and marketing of<br />

these agents Several major companies, such as Yuen-Foongyu Paper Co., Tai-En Co., and Biontech<br />

Inc., have begun to produce and merchandise these products under their own brands.<br />

Although at present the value of this new industry is only about 0.5%–1% of the total traditional<br />

pesticide market, it is growing at the rate of 10%–15% annually. Recently, a brand called Biowork<br />

(Bacillus subtilis) has opened a new market in Japan, and some products of Streptomyces<br />

have created an annual value of TWD10–20 million in the domestic market.<br />

As potted plants become popular in the modern horticultural industry, the use of biofertilizers<br />

has also become more accepted by growers. A culture medium made of vermiculite, peat<br />

moss, and pearlite is quite suitable <strong>for</strong> the application of biofertilizer, since it demands less<br />

fungus and gives better plant growth. Several fungi and bacteria have been studied <strong>for</strong> their<br />

potential as biofertilizer, including the genera Pseudomonas, Bacillus, Thiobaqcillus, Penicillium,<br />

and Aspergillus. There have been some good products marketed by different companies<br />

that have been quite well accepted by farmers. Based on long-term experiments, ARI has also<br />

transferred some of its know-how to different companies. Some of these bacteria are now being<br />

marketed under names such as Dr. Root (Vesicular-arbuscular mycorrhizal fungi, VAMF) by<br />

Tai-En Co., Mycovam (VAMF) by Taiwan Biological Research Co., Ai-gen-how (in Chinese)<br />

(VAMF) by Lei-ju Co., and Agroguard (Bacillus) by the Taiwan Biological Research Co. At<br />

present, the annual value created by the biofertilizer industry is estimated to be slightly less than<br />

that of biopesticides.<br />

GMOs and Other Items<br />

Other products of agricultural biotechnology with high market potential will likely result<br />

from applied molecular biology, also known as genetic engineering, including genetically modified<br />

organisms (GMOs) <strong>for</strong> producing specific bioproducts, detection kits derived from recombinant<br />

DNA techniques, transgenic plants, and transgenic animals. It is believed that applied<br />

molecular biology will create much higher value than ever be<strong>for</strong>e <strong>for</strong> industry and agriculture. In<br />

the Republic of China, great ef<strong>for</strong>t has been taken to promote developments in this field of<br />

research, and much research is ongoing. Using recombinant DNA techniques to produce highly<br />

sensitive and highly accurate detection kits <strong>for</strong> disease analysis is one of the important achievements<br />

of the <strong>Agricultural</strong> Research Institute (ARI). This kind of product was initially developed<br />

several years ago to serve the nursery industry and has now proven very helpful <strong>for</strong> quality<br />

control of tissue cultured plants. Transgenic papaya resistant to papaya ringspot virus was<br />

established by Chung-Hsin University about 10 years ago and passed environmental risk assessment<br />

in 2000. It must still undergo food safety assessment be<strong>for</strong>e being marketed. There are<br />

several transgenic crops, including rice, broccoli, potato, and tomato, now in the process of<br />

undergoing environmental risk assessment at ARI and AVRDC (<strong>Asian</strong> Vegetable Research and<br />

Development Center) but not yet subject to food safety assessment. Another important GM plant<br />

is transgenic eucalyptus, created by the Forest Research Institute, which is now under field<br />

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