28.05.2021 Aufrufe

CHECK Berlin / Brandenburg #5

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ENGLISH<br />

SEXUAL HEALTH<br />

HEPATITIS C<br />

Don‘t be afraid of treatment<br />

Even if in Germany M*SM* (men* who have sex with men*) are not among the<br />

group most severely affected by new hepatitis C infections, a high proportion<br />

of HCV reinfections can be observed after successful therapy. These can<br />

mostly be explained by injurious sexual practices and drug use, particularly<br />

methamphetamine.<br />

Foto: joyfotoliakid_stock.adobe.com<br />

Until 2014 only combination therapies with<br />

pegylated interferon alpha (peg-IFN α) and<br />

ribavirin were available to treat Hepatitis C.<br />

The healing rates were only around 50% and<br />

therapy could sometimes lead to severe physical<br />

and psychological side effects, causing<br />

many to discontinue treatment.<br />

With the introduction of modern, direct antiviral<br />

therapies in 2014, interferon therapies no<br />

longer play a role. In the treatment of hepatitis<br />

C, the development of potent DAA regimes<br />

(Direct-Acting Antiviral Agents) has in fact<br />

made revolutionary progress in recent years.<br />

In particular, the high effectiveness, the good<br />

tolerability and the short duration of treatment,<br />

usually 8–12 weeks, have contributed to<br />

the fact that it is now possible to cure almost<br />

all HCV patients with cure rates of over 95%.<br />

Consequential complications of hepatitis C,<br />

such as progressive liver damage and possible<br />

liver cancer, are thus prevented. Oral ingestion<br />

is uncomplicated, with some therapies only<br />

needing one tablet per day to be taken, sometimes<br />

independently of meals.<br />

98 <strong>CHECK</strong> BERLIN/BRANDENBURG <strong>#5</strong>

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