CHECK Berlin / Brandenburg #5
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ENGLISH<br />
SEXUAL HEALTH<br />
HEPATITIS C<br />
Don‘t be afraid of treatment<br />
Even if in Germany M*SM* (men* who have sex with men*) are not among the<br />
group most severely affected by new hepatitis C infections, a high proportion<br />
of HCV reinfections can be observed after successful therapy. These can<br />
mostly be explained by injurious sexual practices and drug use, particularly<br />
methamphetamine.<br />
Foto: joyfotoliakid_stock.adobe.com<br />
Until 2014 only combination therapies with<br />
pegylated interferon alpha (peg-IFN α) and<br />
ribavirin were available to treat Hepatitis C.<br />
The healing rates were only around 50% and<br />
therapy could sometimes lead to severe physical<br />
and psychological side effects, causing<br />
many to discontinue treatment.<br />
With the introduction of modern, direct antiviral<br />
therapies in 2014, interferon therapies no<br />
longer play a role. In the treatment of hepatitis<br />
C, the development of potent DAA regimes<br />
(Direct-Acting Antiviral Agents) has in fact<br />
made revolutionary progress in recent years.<br />
In particular, the high effectiveness, the good<br />
tolerability and the short duration of treatment,<br />
usually 8–12 weeks, have contributed to<br />
the fact that it is now possible to cure almost<br />
all HCV patients with cure rates of over 95%.<br />
Consequential complications of hepatitis C,<br />
such as progressive liver damage and possible<br />
liver cancer, are thus prevented. Oral ingestion<br />
is uncomplicated, with some therapies only<br />
needing one tablet per day to be taken, sometimes<br />
independently of meals.<br />
98 <strong>CHECK</strong> BERLIN/BRANDENBURG <strong>#5</strong>