Self-assembled Transition Metal Coordination Frameworks of ...

A Self-Assembled Transition Metal Coordination
showed cell proliferation and their complexation leads to antiproliferation effect.
Three complexes are reported as anticancer gadgets against breast cancer.
Chapter 5 explains the synthesis and spectral characterization of five Mn(lI)
complexes. Variable temperature magnetization study reveals strong antiferromagnetism.
Frozen DMF solution EPR spectral studies suggesting possible fragmentations to
monomeric species, under investigation conditions, as evidenced by EPR parameters
obtained by making use of simulations. MALDI MS spectra reveal lower stability of
Mn(lI) complexes in their solutions or under MALDI ionization conditions, but show
sensible fragmentation peaks. Magnetic data of four Mn(II) complexes were rationalized
successfully on the basis of expected square grid structures in the solid state, as supported
by mass and other studies, and is in agreement.
Chapter 6 deals the syntheses and characterization of six Zn(II) and two Cd(lI)
complexes. All complexes, except two Zn( ll) compounds, exist as molecular square grids
and their structural and spectral features are described in detail. This include single crystal
X-ray diffraction study of one Zn(ll) molecular square grid derived from a
carbohydrazone ligand, H2L5. The results clearly indicate the utility of carbohydrazones as
building blocks for self-assembled molecular frameworks. The MALDI MS spectrometry
is found an important tool for the explicit characterization, existence and stability of
framework complexes in solutions and can be confirmed by theoretical simulations of
isotropic distribution pattems of characteristic peaks.
Based on the present work we would like to conclude that the carbohydrazones,
thiocarbohydrazones and their coordination framework complexes of transition metals are
promising systems for wide application in science and technology varied from physics to
biotechnology. Novel classes of materials and biologically important potential compounds
open up further scope of researches and we hopefully welcome any sort of related research
to make this work more valuable.
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