14th ICID - Poster Abstracts - International Society for Infectious ...

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When citing these abstracts please use the following reference: Author(s) of abstract. Title of abstract [abstract]. Int J Infect Dis 2010;14S1: Abstract number. Please note that the official publication of the International Journal of Infectious Diseases 2010, Volume 14, Supplement 1 is available electronically on http://www.sciencedirect.com Final Abstract Number: 29.001 Session: Malaria & Blood-borne Parasites Date: Wednesday, March 10, 2010 Time: 12:30-13:30 Room: Poster & Exhibition Area/Ground Level Type: Poster Presentation A study of acute myocardial infarction in a hospital cohort of malaria: 4 years retrospective analysis K. Jain 1 , D. C. M. 2 1 JSS Medical college and hospital, Mysore, Karnataka, India, 2 Kasturba Medical college, mangalore, mangalore, Karnataka, India Background: Malaria, a protozoal disease, caused by genus plasmodium, is prevalent in about 100 countries worldwide & is a major cause of morbidity & mortality especially in sub Saharan Africa, Southeast Asia & Latin-America. Myocardial infarction has not been recognized as a complication of malaria though there have been reports of myocardial involvement in experimental studies and in postmortem findings. The objective of the present study was to analyze the association of acute myocardial infarction (AMI) in malaria patients Methods: Retrospective observational study of 38,919 in-patients of Dr. TMA Pai Rotary Hospital was done from the year 1995 to 1998. Analysis had been started from 1995 as malaria resurged in Mangalore city from 1995 onwards. A year wise categorizations of patients were done & occurrence of AMI among patients with malaria was compared with the occurrence of AMI among all other in-patients for each year & cumulatively. Diagnosis of malaria cases had been established by QBC test. Diagnosis of myocardial infarction had been established by following standard ECG changes and cardiac biomarkers profile. After tabulation, p value has determined by applying standard Gaussian test. p value
When citing these abstracts please use the following reference: Author(s) of abstract. Title of abstract [abstract]. Int J Infect Dis 2010;14S1: Abstract number. Please note that the official publication of the International Journal of Infectious Diseases 2010, Volume 14, Supplement 1 is available electronically on http://www.sciencedirect.com Final Abstract Number: 29.002 Session: Malaria & Blood-borne Parasites Date: Wednesday, March 10, 2010 Time: 12:30-13:30 Room: Poster & Exhibition Area/Ground Level Type: Poster Presentation Severe malaria in East Kalimantan, Indonesia C. gunawan 1 , P. D. Nasution 2 , A. R. Magdaleni 2 1 Indonesian Malaria Expert Committee/ Mulawarman University School of Medicine/ A. Wahab Sjahranie General Hospital, Samarinda, Indonesia, 2 Mulawarman University School of Medicine, samarinda, Indonesia Background: Malaria is endemic in many provinces in Indonesia, especially in Eastern Region, where 35 % of population live in areas with risk of getting infected by malaria. Mortality of severe malaria reported in Indonesia is 10 – 30 %. Abdul Wahab Sjahranie General Hospital, Samarinda is the top referral hospital in East Kalimantan Province that manage many severe malaria patients sent from some districts around Samarinda. Objectives. To know the features of severe malaria patients treated at Abdul Wahab Sjahranie General Hospital Samarinda. Methods: An observational study was performed on severe malaria patients treated at the Department of Internal Medicine of Abdul Wahab Sjahranie General Hospital, Samarinda during 2 years (January 2007 – December 2008). Severe malaria was diagnosed based on WHO criteria (positive microscopic examination of Plasmodium falciparum with one or more complications). Anti malarial drug given was quinine infusion 10 mg/ kg BW/ 8 hours for at least 48 hours, and then continued with sulfate quinine tablet if patients could take oral medicines until 7th day. Results: There were 47 severe malaria patients treated in this hospital during 2 years, consisting of 43 males (91.5 %) and 4 females (8.5 %). All patients worked or lived in the forest areas out of Samarinda. Patients ages` were 13 - 63 years, most of them were 20 – 40 years (57.5 %). The most common complications found were jaundice (72.3 %), cerebral malaria (40.4 %), acute renal failure (31.9 %), while severe anemia was only 6.4 %. Most patients had 1 complication (63.8 %), while patients with 2 complications were 21.3 %, and patients with 3 or more complications were 14.9 %. Mortality of patients with 1 complication, 2 complications, 3 or more complications were 6.7 %, 10.0 %, 71.4 %, respectively. Overall mortality rate was 17.0 %. Conclusion: Almost all severe malaria patients treated in Samarinda are males (91.5 %) in productive ages (20 – 40 years). Jaundice, cerebral malaria and acute renal failure are the most common complications found. Mortality is related to the number of complications found, whereas patients with 3 or more complications have very high mortality rate (above 70 %). Overall mortality rate of severe malaria cases is 17.0 %.
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