14th ICID - Poster Abstracts - International Society for Infectious ...

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When citing these abstracts please use the following reference: Author(s) of abstract. Title of abstract [abstract]. Int J Infect Dis 2010;14S1: Abstract number. Please note that the official publication of the International Journal of Infectious Diseases 2010, Volume 14, Supplement 1 is available electronically on http://www.sciencedirect.com Final Abstract Number: 29.005 Session: Malaria & Blood-borne Parasites Date: Wednesday, March 10, 2010 Time: 12:30-13:30 Room: Poster & Exhibition Area/Ground Level Type: Poster Presentation APACHE III score as a prognostic marker in severe malaria in a tertiary care hospital from south India K. Nataraj 1 , M. Prabhu 2 , M. Sangar 2 , B. Ramachandran 2 1 NRS Medical College, Kolkata, West Bengal, India, 2 KMC Manipal, Manipal, Karnataka, India Background: Malaria is a most common parasitic infection with transmission in 103 countries affecting > 1 billion people and causing between 1 and 3 million deaths each year. Falciparum malaria causing severe malaria is one of the commonest infections with high mortality in India in spite of potent chemotherapy. APACHE III is the most recent version of the scoring system developed by Knaus and colleagues. So far no studies are available using APACHE III in severe malaria in Indian setting Aims: Prospective clinical study of APACHE III score as a predictor of mortality in patients with severe Malaria. Methods: 41 patients with diagnosis of severe Malaria admitted in Kasturba Hospital Manipal, tertiary care hospital during the period of May 2006 to June 2008 Statstics:SPSS 15.3 was used to perform statistics, depending on the normalcy of distribution curve and skew deviation mean or median was compared using Independent T test or Non parametric t test such as Mann Whitney’s were used respectively. Results: During 2 year study period (May 2006- June 2008) 41 patients with Severe Malaria were admitted in different ICUs of Kasturba Hospital, of whom6 were females and 35 were males.11 patients succumbed to their illness and 30 survived. There was no significant difference in age and parasite index in patients who survived and succumbed to illness. Clinical parameters like tachycardia, hypotension and hypoxia were significantly seen in patients who succumbed to illness. Neurological obtundation was seen in all 11 dead patients at presentation is another independent variable predictive of severe malaria Among lab parameters thrombocytopenia, raised BUN, Creatinine, low blood sugars were significant predictive factors for mortality. Most patients 10 out of 11 had lung involvement with ARDS required ventilation. Mean APACHE III scoring among alive patients was 50.94 ± 17.25 and among dead patients was 100.18 ± 26.86.The scores were compared by using Independent T test and the scores were highly statistically significant (p
When citing these abstracts please use the following reference: Author(s) of abstract. Title of abstract [abstract]. Int J Infect Dis 2010;14S1: Abstract number. Please note that the official publication of the International Journal of Infectious Diseases 2010, Volume 14, Supplement 1 is available electronically on http://www.sciencedirect.com Final Abstract Number: 29.006 Session: Malaria & Blood-borne Parasites Date: Wednesday, March 10, 2010 Time: 12:30-13:30 Room: Poster & Exhibition Area/Ground Level Type: Poster Presentation Poor impact of the primary health care (PHC) on malaria control in rural communities of Southeast Nigeria O. Odikamnoro Ebonyi State University, Abakaliki, Ebonyi, Nigeria Background: Malaria is a disease of poverty and low socio-economic status and these conditions abound in developing countries. This means that the successful implementation of malaria control programmes requires a certain level of basic health services. In countries where malaria is a serious impediment to socio-economic progress, emphasis should be on malaria control rather tan eradication. This will reduce the burden of the disease and pave the way for the speeding up of socio-economic development which may in the long run contribute to a future eradication of malaria. The resurgence of malaria is a global phenomenon. Most studies on malaria have dealt with clinical, laboratorial and entomological aspects. Few studies have dealt with human factors. Methods: 2400 volunteers from all age- groups from selected endemic rural communities of southeast Nigeria were screened for malaria parasitaemia from June 2008 to August 2009, using the thin and thick smear microscopy. Following this, 16 close-ended questionnaire items were generated and administered on 600 adults, mainly heads of households to assess their knowledge, attitudes,and practices on the various aspects of malaria transmission, management and control, thus evaluate the impact of the Primary Health Care on malaria control in the study areas. Results: The results showed the following percentage infection in the varous age-groups: 0-11 months (24%); 1year-2years (43%); 2-4 years (80%); 5-9 years (74%); 10-14 years (71%); 15 years and above (68%). A total of 1440 persons were positive for Plasmodium falciparum parasitaemia, representing an average infection of 60%. In the questionnaires, 93% of the respondents did not associate malaria with mosquito bite; 60% were not carrying out any form of vector control; only 7% had adequate knowledge of the management of fever, and 15% had any knowledge of government action towards the control of malaria. Conclusion: The study revealed poor implementation of the Primary Health Care as it concerns malaria control at the peripheral level. The remoteness of some rural communities and lack of easy accessibility makes it difficult for health progrmmes to get to the grassroot. There is the need to train a large number of Village-Based Health Volunteers , who should step up community mobilizaion and health education campaigns . Parents should know how to prevent and manage malaria fever in their children.
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