14th ICID - Poster Abstracts - International Society for Infectious ...

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When citing these abstracts please use the following reference: Author(s) of abstract. Title of abstract [abstract]. Int J Infect Dis 2010;14S1: Abstract number. Please note that the official publication of the International Journal of Infectious Diseases 2010, Volume 14, Supplement 1 is available electronically on http://www.sciencedirect.com Final Abstract Number: 33.006 Session: Tuberculosis: Epidemiology, Prevention & Control Date: Wednesday, March 10, 2010 Time: 12:30-13:30 Room: Poster & Exhibition Area/Ground Level Type: Poster Presentation HIV prevalence and MDR TB among DOTS attendees in a rural area of Haryana, India R. kumar, S. Rai, S. Kant, K. Anand, L. Dar, U. Singh All India Institute of Medical Sciences, New Delhi, Delhi, India Background: MDR-TB was a potential threat to tuberculosis control in India. We wanted to estimate the prevalence of HIV infection and MDR TB among DOTS attendees in Ballabgarh, Haryana, India. Methods: The study was carried out in two DOTS centres of Ballabgarh Tehsil of district Faridabad, Haryana. It was a health facility based cross sectional survey. Study subjects were all TB patients (Pulmonary and Extra Pulmonary) who were registered for DOTS. Data was collected from January 2007 to June 2008. We enrolled 413 eligible patients who were informed about the study objectives and written consent was obtained. All patients were offered free Liver Function Test. Unlinked anonymous testing on aliquot of LFT blood samples was performed after removing all identifiers. HIV testing was done using three E/R/S. Sputum was collected from patients belonging to Categories I and II, under Revised National TB Programme. Anti TB sensitivity testing was done on randomly selected patients of Category I (50 % of patients) and all of the Category II patients. Results: Four hundred and thirteen TB patients [CAT I-220(53.3%), II-101(24.5%), and III-92 (22.2%)] were interviewed and blood samples could be obtained from 368 patients (89.1%). Four blood samples got contaminated and labels of ten samples was lost during the transportation. Finally, of the 354 samples tested two were found HIV sero reactive. Prevalence of HIV among TB patients was 0.56% (95 % CI 0.068-2.02). Sputum collection was attempted from 211 patients. Thirty eight patients (18%) had difficulty in producing sputum. Of the 173 sputum samples collected, eighty were culture positive for Mycobacterium tuberculosis. Among them nine samples were found to be multi drug resistant by RLBA. The prevalence of MDR among TB patients was 11.25 % (95 % CI 5.27 – 20.28). Conclusion: HIV prevalence was low and similar to the rate observed among pregnant women (0.13%) who could be considered as proxy to general low risk population. Multi drug resistance was high among TB patients. It was reassuring that HIV – TB co infection was low and none of the MDR TB patients were HIV positive.
When citing these abstracts please use the following reference: Author(s) of abstract. Title of abstract [abstract]. Int J Infect Dis 2010;14S1: Abstract number. Please note that the official publication of the International Journal of Infectious Diseases 2010, Volume 14, Supplement 1 is available electronically on http://www.sciencedirect.com Final Abstract Number: 33.007 Session: Tuberculosis: Epidemiology, Prevention & Control Date: Wednesday, March 10, 2010 Time: 12:30-13:30 Room: Poster & Exhibition Area/Ground Level Type: Poster Presentation The social representation of DOT-related tuberculosis by patients of Guarulhos at the metropolitan area of Sao Paulo, Brazil V. Souza Pinto, V. M. N. Galesi, M. I. P. S. Braz Sao Paulo State Secretary of Health, Sao Paulo, SP, Brazil Background: Setting: Public healthcare service (HCS) of Guarulhos municipality, in the metropolitan area of Sao Paulo, Brazil. Objective: Analyzing the individual perception of patients concerned to supervised treatment (DOT)-related tuberculosis (TB) offered by HCS. Methods: Qualitative approach using interviews with patients. The Collective Discourse (CD) allows capturing a pool of social representations, gathering answers from different individuals with discourse content of similar sense to build collective statements. Results: Answers of 65 patients (interviewers can give more than one central idea), in three questions (Q) about DOT – (Q1) ‘Someone tells you about DOT. What is DOT for you?’; (Q2) ‘Tell us about DOT on a daily basis?’; and (Q3) ‘DOT takes six months and after one month patients do not have more symptoms. Why do you think this happen?’. According to Table 1, the central ideas presented were: Q1, (A) It's a guidance regarding where treatment will take place; (B) B. It's a guidance regarding time and frequency of TB drugs; and (C) It's an explanation about TB. Q2, (A) Patients report to go to HCS to take TB drugs; (B) Patients report the side-effects to TB drugs and to the aggressive treatment; (C) Patients report that treatment is incorporated on routine and do not affect the routine; and (D) Patients report improvement of health condition after the beginning of treatment. Q3, (A) Because symptoms decrease or disappear and patients feel good and think they’re cured; (B) Due to lack of consciousness and responsibility and lack of love to life, health and to the next one; (C) Due to side effects and lack of information regarding the treatment of TB. Conclusion: TB patients have correct knowledge about the disease, understanding the necessity of DOT and also they report their ways on the process of TB diagnosis which can compromise their treatments. So, it is necessary that HCS pay attention on TB diagnosis with commitment and training of professionals on DOTS Strategy. They don’t perceive DOT as a barrier, but as a strengthening for a very difficult treatment.
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