14th ICID - Poster Abstracts - International Society for Infectious ...

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When citing these abstracts please use the following reference: Author(s) of abstract. Title of abstract [abstract]. Int J Infect Dis 2010;14S1: Abstract number. Please note that the official publication of the International Journal of Infectious Diseases 2010, Volume 14, Supplement 1 is available electronically on http://www.sciencedirect.com Final Abstract Number: 33.010 Session: Tuberculosis: Epidemiology, Prevention & Control Date: Wednesday, March 10, 2010 Time: 12:30-13:30 Room: Poster & Exhibition Area/Ground Level Type: Poster Presentation Frequency of tuberculosis in the biggest island of the Persian Gulf K. Hamdi 1 , A. Shoae Hassani 2 , A. Akhavan Sepahi 3 1 Young Researchers Club (YRC) of Islamic Azad university, Tehran, Iran, Islamic Republic of, 2 Islamic Azad University (IAU), Fars, Iran, Islamic Republic of, 3 Tehran North Branch of IAU, tehran, Iran, Islamic Republic of Background: Despite availability antituberculosis drugs for almost 50 years, tuberculosis (TB) continues to exert an enormous toll on world health. The incidence of TB is increasing all over the world. Qeshm represents a region in south of Iran that is the biggest island in the Persian gulf with 23 thousands inhabitants with a long tradition in TB control, including a centralization of the bacteriological diagnostic facility. The present study was intended to analyze the transmission of Mycobacterium tuberculosis by a combination of conventional epidemiological approaches. Methods: Mycobacterium tuberculosis analyzed in this study were collected at the Health Care Center in Qeshm, Iran. A total of 81 new, bacteriologically verified TB cases were registered in Qeshm Island between 2003 and 2008. All the isolates were examined for their susceptibility to ethambutol, isoniazid, streptomycin, rifampin, and pyrazinamide by using a radiometric culture system (BACTEC). The data obtained from the cultures analyses were interpreted by using demographic data, such as age, sex, ethnicity, and residence, for the patients. The risk factors among the patients for being part of an active chain of transmission, as opposed to demonstrating reactivation of a previously acquired latent infection, were estimated by statistical analyses (SPSS). Results: A total of 81 clinical isolates belonging to patients having pulmonary and extra pulmonary tuberculosis were collected during Jan 2003 to Nov 2008. The incidence of tuberculosis in female was 25.9% and in male was 74.1%. This survey observed 47.1% of immigrated Afghans and 39.1% of Pakistanis were infected with tuberculosis. Regarding the literacy 57% were unlettered. 91.7% of people referring to health center were new patients. 68.8% people were infected with pulmonary tuberculosis. The peoples over 60 year were highest group infected to pulmonary tuberculosis (30.4%) and age groups 30-44 were highest the cases infection external pulmonary tuberculosis. The major chains of recent transmission were localized to distinct geographical regions in the area. Conclusion: TB is frequent among immigrants, especially from Afghanistan and Pakistan, but it is apparently readily suspected, diagnosed, and treated by the health care system. Indigenous patients with pulmonary symptoms are not primarily suspected to have TB and, therefore, play an important role in recent TB transmission in Qeshm.
When citing these abstracts please use the following reference: Author(s) of abstract. Title of abstract [abstract]. Int J Infect Dis 2010;14S1: Abstract number. Please note that the official publication of the International Journal of Infectious Diseases 2010, Volume 14, Supplement 1 is available electronically on http://www.sciencedirect.com Final Abstract Number: 33.011 Session: Tuberculosis: Epidemiology, Prevention & Control Date: Wednesday, March 10, 2010 Time: 12:30-13:30 Room: Poster & Exhibition Area/Ground Level Type: Poster Presentation The clinical and epidemiological characteristics of Mycobacterium tuberculosis Beijing/W family strains in a major immigrant-receiving province of Canada D. Langlois-Klassen 1 , D. Kunimoto 1 , D. Saunders 1 , J. Boffa 1 , L. Chui 2 , R. Long 1 1 University of Alberta, Edmonton, AB, Canada, 2 Alberta Provincial Laboratory for Public Health, Edmonton, AB, Canada Background: Tuberculosis resulting from the Beijing/W family of Mycobacterium tuberculosis strains is a global concern due to associations with tuberculosis outbreaks, antituberculosis drug resistance, and treatment failure and relapse. This study sought to determine if Beijing/W stains represent an emerging public health threat within Canada, a major immigrant-receiving country with low tuberculosis incidence. Methods: This population-based cohort study investigated archived culture-positive M. tuberculosis isolates from cases diagnosed in the province of Alberta, Canada between 1990 and 2007. Isolates were Beijing/W genotyped with PCR-based region of difference analysis and DNA fingerprinted with IS6110 RFLP. In 449 isolates, Beijing/W status was validated with spoligotyping. Demographic and clinical data for each isolate was obtained from the provincial TB Registry. Statistical analyses consisted of Pearson’s chi-square test, Fisher’s exact test, and independent sample t-test. Results: Nearly 99% (n=1,900/1,927) of isolates were available for genotyping. Beijing/W strains comprised 19% (n=372) of isolates, with foreign-born persons contributing 91% (n=337) of all Beijing/W isolates (p
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