14th ICID - Poster Abstracts - International Society for Infectious ...

When citing these abstracts please use the following reference:
Author(s) of abstract. Title of abstract [abstract]. Int J Infect Dis 2010;14S1: Abstract number.
Please note that the official publication of the International Journal of Infectious Diseases 2010, Volume 14, Supplement 1
is available electronically on http://www.sciencedirect.com
Final Abstract Number: 30.026
Session: Mycology, Fungal Infections and Antifungal Drugs
Date: Wednesday, March 10, 2010
Time: 12:30-13:30
Room: Poster & Exhibition Area/Ground Level
Type: Poster Presentation
Candidemia in third level hospitals in Bogotá, Colombia
J. Cortes 1 , P. Reyes 1 , C. H. Gomez 2 , S. I. Cuervo 1 , P. Rivas 3 , R. Sanchez 1
1 Universidad Nacional de Colombia, Bogota, Colombia, 2 Hospital Universitario San Ignacio,
Bogota, Colombia, 3 Instituto Nacional de Cancerologia, Bogota, Colombia
Background: Candidemia is a serious infectious complication among critical and
immunosupressed patients.
Methods: Patients with laboratory confirmed candidemia were prospectively followed. Candida
isolates were sent to a reference laboratoryfor identification and susceptibility.Risk factors and
clinical data were taken from the medical record. Antifungal use and final outcome were
registered.
Results: 131 episodes were followed, 61% women, with ages between 9 days and 87 years.
50% of blood cultures were positive after 34 hours (in 44% of the patients blood cultures were
posiitve in more than one bottle). More frequently found risk factors for candidemia were stay in
ICU 78%), previous antibiotic use (77%), parenteral nutrition (54%), previous abdominal surgery
(40%), previous use of immunosuppresors (29%). Candida species identifies were C. albicans
(67%), followed by C. parapsilosis (14%) and C. tropicalis (10%). Susceptibility to fluconazole
were high among C. albicans and C. tropicalis isolates, but not for the other Non-albicans
isolates. Fluconazole was the preferred drug of choice (57%), followed by amphotericin
deoxycholate (18%). 18% of the patients never received antifungal therapy. Mortality was high
after two weeks of treatment (20%) and was even higher at discharge (36%).
Conclusion: Candidemia is a severe complication with high mortality. In Colombia, a high
proportion of patients never received antifungal therapy even with laboratory proven infection.