Gastroprotective Triterpenoids: Pharmacological Mechanism [25] Tanaka, T; Guth, PH. Role <strong>of</strong> gastric mucosal blood flow in gastroprotective effect <strong>of</strong> novel xanthine derivative. Digestive Disease Science, 1994, 39(3), 587-592. [26] Takeuchi, K; Tanaka, A; Hayashi, Y; Kubo, Y. Functional mechanism underlying COX-2 expression following administration <strong>of</strong> indomethacin in rat stomachs: importance <strong>of</strong> gastric hipermotility. Digestive Disease <strong>and</strong> Science, 2004, 49 (2), 180-187. [27] Bortolotti, M; Mari, C; Lopilato, C; La Rovere, L; Miglioti, M. Sildenafil inhibits gastroduodenal motility. Alimentary Pharmacology <strong>and</strong> Therapeutics, 2001, 15, 157- 161. [28] Rosalmedia, MC; Saraiva, LD; Graςa, JR; Barreto, BI; Da Nóbrega, MV; Gondim, FA; Rola, FH; Santos, AA. Sildenafil a phosphodiesterase-5 inhibitor, delays gastric emptying <strong>and</strong> gastrointestinal transit <strong>of</strong> liquid in awake rats. Digestive Disease <strong>and</strong> Sciences, 2003, 48, 2064-2068. [29] Filaretova, L; Podvigina, T; Bagaeva, T; Bobryshev, P. Gastroprotective role <strong>of</strong> glucorticoid hormones. Journal <strong>of</strong> Pharmacological Sciences, 2007, 104, 195-201. [30] Serhan, CN. Eicosanoids. In: William J. Koopman. Arthritis <strong>and</strong> allied conditions. Birmingham, Alabama, USA. Lippincott Williams & Wilkins, 2001. [31] Li, Y; Smith, T; Gasbski, S. The membrane association sequences <strong>of</strong> the prostagl<strong>and</strong>in endoperoxide synthases-1 <strong>and</strong> 2 isozymes. Journal <strong>of</strong> Biological Chemistry, 1998, 273, 29830-29837. [32] Wallace, JL; Devch<strong>and</strong>, PR. Emerging roles for cyclooxygenase-2 in gastrointestinal mucosal defense. British Journal <strong>of</strong> Pharmacology, 2005, 145, 275-282. [33] Wallace, JL; Keenan, CM; Granger, DN. Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil-dependent process. American Journal <strong>of</strong> Physiology, 1990, 259, G462-G467. [34] Warner, TD; Giuliano, F; Vojnovic, I; Bukada, A; Mitchell, JA; Vane, JR. Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proceedings National Academy <strong>of</strong> Sciences, 1999, 96, 7563-7568. [35] Wallace, JL; McKnight, W; Reuter, BK; Vergnolle, N. NSAID-induced gastric damage in rats: requirement for inhibition <strong>of</strong> both cyclooxygenase 1 <strong>and</strong> 2. Gastroenterology, 2000, 119 (3), 706-714. [36] Mizuno, H; Sakamoto, C; Matsuda, K; Waka, K; Uchida, T; Noguchi, H; Akamatsu, T; Kasuga, M. Induction <strong>of</strong> cyclooxygenase 2 in gastric mucosal lesion <strong>and</strong> its inhibition by the specific antagonist delays healing mice. Gastroenterology, 1997, 112, 387-397. [37] Whittle, BJR; López-Belmonte, J. Action <strong>and</strong> interaction <strong>of</strong> endothelins, prostacyclin <strong>and</strong> nitric oxide in the gastric mucosa. Journal <strong>of</strong> Physiology <strong>and</strong> Pharmacology, 1993, 44, 91-107. [38] Tannenbaum, SR; Weisman, M; Fett, D. The effect <strong>of</strong> nitrate intake on nitrite formation in human saliva. Food <strong>and</strong> Cosmetics Toxicology, 1976, 14, 549-552. [39] Duncan, C; Li, H; Dykhuizen, R; Frazer, R; Johnston, P; MacKnight, G; Smith, L; Lamza, K; McKenzie, H; Batt, L; Kelly, D; Golden, M; Benjamin, N; Leifert, C. Protection against oral <strong>and</strong> gastrointestinal diseases: importance <strong>of</strong> dietary nitrate 129
130 Aracely E. Chávez-Piña <strong>and</strong> Andrés Navarrete intake, oral nitrate reduction <strong>and</strong> enterosalivary nitrate circulation. Comparative Biochemistry <strong>and</strong> Physiology A, 1997, 118, 939-948. [40] Lundberg JO; Weitzberg, E; Lundberg JM, Alving, K. Intragastric nitric oxide production in humans: measurements in expelled air. Gut, 1994, 35, 1543-1546. [41] MacNaughton, WK; Cirino, G; Wallace JL. Endothelium-derived relaxing factor (nitric oxide) has protective actions in the stomach. Life Science, 1989, 45, 1869-1876. [42] Wallace, JL; Cirino, G. The development <strong>of</strong> gastrointestinal-sparing non-steroidal antiinflammatory drugs. Trends in Pharmacological Sciences, 1994, 15, 405-406. [43] Hawkey, CJ; Jones, JI; Atherson, CT; Skelly, MM; Bebb, JR; Fagerholm, U; Jonzon, B; Karlsson, P; Bjarnason, IT. Gastrointestinal safety <strong>of</strong> AZD3582, a cyclooxygenase inhibiting nitric oxide donator: pro<strong>of</strong> <strong>of</strong> concept study in humans. Gut, 2003, 52, 1537-1542. [44] Konturek, PC; Brzozowski, T; Kani, J; Konturek, SJ; Hahn, Eg. Nitric oxide-releasing aspirin protects gastric mucosa against ethanol damage in rats with functional ablation <strong>of</strong> sensory nerves. Inflammation research, 2003, 52, 359-365. [45] Wallace, JL; Muscará, MN; de Nucci, G; Zamuner, S; Cirino, G; del Soldato, P; Ongini, E. Gastric tolerability <strong>and</strong> prolonged prostagl<strong>and</strong>in inhibition in the brain with a nitric oxide-releasing flurbipr<strong>of</strong>en derivative, NCX-2216 [3-[4-(2-fluoro-α-methyl- [1,1´-biphenyl]-4-acetyloxy)-3-methozyphenyl]-2-propenoic acid 4-nitrooxy butyl ester]. The Journal <strong>of</strong> Pharmacology <strong>and</strong> Experimental Therapeutics, 2004, 309, 626-633. [46] Wallace, JL; McKnight, W; Wilson, TL; del Soldato, P; Cirino, G. Reduction <strong>of</strong> shockinduced gastric damage by a nitric oxide-releasing aspirin derivative: role <strong>of</strong> neutrophils. American Journal <strong>of</strong> Physiology <strong>and</strong> Gastrointestinal Liver Physiology, 1997, 273, 1246-1251. [47] Fierro, IM; Serhan, CN. Mechanism in anti-inflammation <strong>and</strong> resolution: the role <strong>of</strong> lipoxins <strong>and</strong> aspirin-triggered lipoxins. Brazilian Journal <strong>of</strong> Medical <strong>and</strong> Biological Research, 2001, 34(5), 555-566. [48] Claria, J; Serhan, CN. Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions. Proceedings <strong>of</strong> the National Academy <strong>of</strong> Sciences, 1995, 92, 9475-9479. [49] Shimokawa, T; Smith, WL. Prostagl<strong>and</strong>in endoperoxide synthase. The aspirin acetylation region. Journal <strong>of</strong> Biological Chemistry, 1992, 267, 12387-12392. [50] Mancini, JA; O´Neill, GP; Bayly, C; Vickers, PJ. Mutation <strong>of</strong> serine-516 in human prostagl<strong>and</strong>in G/H synthase-2 to methionine or aspirin acetylation <strong>of</strong> this residue stimulates 15-R-HETE synthesis. FEBS Letters 1994, 342, 33-37. [51] Perreti, M; Chiang, N; La, M; Fierro, IM; Marullo, S; Getting, SJ; Solito, E; Serhan, CN. Endogenous lipid- <strong>and</strong> peptide-derived anti-inflammatory pathways generated with glucocorticoid <strong>and</strong> aspirin treatment activate the lipoxin A4 receptor. Nature Medicine, 2002, 8, 1296-1302. [52] Serhan, CN. Lipoxin biosynthesis <strong>and</strong> its impact in inflammatory <strong>and</strong> vascular events. Biochimica et biphysica acta, 1994, 1212, 1-25.
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BIOTECHNOLOGY IN AGRICULTURE, INDUS
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Industrial Biotechnology Shara L. A
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Copyright © 2009 by Nova Science P
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viii Contents Chapter 8 Pharmacolog
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x Alejandro Varela and Jasiah Ibañ
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xii Alejandro Varela and Jasiah Iba
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xiv Alejandro Varela and Jasiah Iba
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In: Medicinal Plants: Classificatio
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Biological Effects of -Carotene acy
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Biological Effects of -Carotene cry
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Biological Effects of -Carotene fla
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Biological Effects of -Carotene Osh
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50 Gustavo J. Martínez, Mara Sato
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52 Gustavo J. Martínez, Mara Sato
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54 Gustavo J. Martínez, Mara Sato
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56 Gustavo J. Martínez, Mara Sato
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58 [2] Gustavo J. Martínez, Mara S
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60 Gustavo J. Martínez, Mara Sato
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62 Gustavo J. Martínez, Mara Sato
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64 Gustavo J. Martínez, Mara Sato
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66 Gustavo J. Martínez, Mara Sato
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68 Gustavo J. Martínez, Mara Sato
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70 Gustavo J. Martínez, Mara Sato
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Huperzia saururus (Lam.) Trevis. Mi
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74 Gustavo J. Martínez, Mara Sato
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76 Gustavo J. Martínez, Mara Sato
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180 Vandana Gulati, Ian H. Harding
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182 Vandana Gulati, Ian H. Harding
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184 Vandana Gulati, Ian H. Harding
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186 Vandana Gulati, Ian H. Harding
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In: Medicinal Plants: Classificatio
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Biomolecules with Anti-Mycobacteria
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Biomolecules with Anti-Mycobacteria
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Biomolecules with Anti-Mycobacteria
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204 Chien-Yi Chen Ligusticum chuanx
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206 Chien-Yi Chen (IAEA 336), also
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208 Chien-Yi Chen 4. Results and Di
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210 4.3. Fresh Leaves and Stems Chi
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212 Chien-Yi Chen collected from na
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214 Chien-Yi Chen primary enzyme in
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216 Chien-Yi Chen [20] Liu SM, Chun
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218 S.M.M. Vasconcelos, J.E.R. Hon
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220 S.M.M. Vasconcelos, J.E.R. Hon
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222 S.M.M. Vasconcelos, J.E.R. Hon
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224 S.M.M. Vasconcelos, J.E.R. Hon
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226 S.M.M. Vasconcelos, J.E.R. Hon
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228 S.M.M. Vasconcelos, J.E.R. Hon
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230 S.M.M. Vasconcelos, J.E.R. Hon
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232 S.M.M. Vasconcelos, J.E.R. Hon
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234 S.M.M. Vasconcelos, J.E.R. Hon
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236 S.M.M. Vasconcelos, J.E.R. Hon
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238 S.M.M. Vasconcelos, J.E.R. Hon
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240 S.M.M. Vasconcelos, J.E.R. Hon
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242 S.M.M. Vasconcelos, J.E.R. Hon
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244 Sônia Sin Singer Brugiolo, Luc
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246 Sônia Sin Singer Brugiolo, Luc
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248 Sônia Sin Singer Brugiolo, Luc
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250 Sônia Sin Singer Brugiolo, Luc
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252 Sônia Sin Singer Brugiolo, Luc
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254 Sônia Sin Singer Brugiolo, Luc
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256 C.W. Huck and G.K. Bonn Keyword
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258 C.W. Huck and G.K. Bonn No addi
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260 C.W. Huck and G.K. Bonn The rob
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262 C.W. Huck and G.K. Bonn Validat
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264 Naphthodianthrones C.W. Huck an
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266 C.W. Huck and G.K. Bonn Figure
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268 C.W. Huck and G.K. Bonn Figure
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270 C.W. Huck and G.K. Bonn hierarc
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272 C.W. Huck and G.K. Bonn [17] Hu
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In: Medicinal Plants Classification
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What is the Future of Phytotherapy?
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In: Medicinal Plants Classification
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Quality Control of Polysaccharides
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Quality Control of Polysaccharides
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Quality Control of Polysaccharides
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Quality Control of Polysaccharides
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Quality Control of Polysaccharides
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Quality Control of Polysaccharides
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Quality Control of Polysaccharides
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Origins Targets Neisseria meningiti
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Quality Control of Polysaccharides
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Quality Control of Polysaccharides
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Quality Control of Polysaccharides
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Quality Control of Polysaccharides
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Quality Control of Polysaccharides
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Quality Control of Polysaccharides
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Quality Control of Polysaccharides
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Quality Control of Polysaccharides
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316 Philippe N. Okusa, Caroline Ste
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318 Philippe N. Okusa, Caroline Ste
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320 2.7. General Toxicity Tests Phi
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322 Philippe N. Okusa, Caroline Ste
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324 Philippe N. Okusa, Caroline Ste
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326 Philippe N. Okusa, Caroline Ste
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328 Philippe N. Okusa, Caroline Ste
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330 Philippe N. Okusa, Caroline Ste
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332 Philippe N. Okusa, Caroline Ste
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334 Philippe N. Okusa, Caroline Ste
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336 Philippe N. Okusa, Caroline Ste
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338 age-related macular degeneratio
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340 B lymphocytes, 7 babies, 60, 62
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342 cell surface, 229 cellular adhe
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344 cultivation, 75, 76, 83, 85, 14
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346 embryonic stem cells, 47 emotio
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348 gas, xiii, 21, 104, 131, 145, 1
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350 high-performance liquid chromat
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352 institutions, 84 instruments, 2
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354 lung, ix, 1, 6, 16, 17, 22, 23,
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356 mucosa, x, 2, 19, 97, 98, 99, 1
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358 oxidative, 4, 8, 9, 10, 12, 13,
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360 polyunsaturated fatty acids, 10
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362 Reserpine, 328 reservation, 143
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364 SPT, 135 squamous cell carcinom
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366 transcription, 8, 35, 152 trans