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Biosyntheses <strong>and</strong> Bioactivities <strong>of</strong> Flavonoids in the <strong>Medicinal</strong>...<br />

Table 2. Bioactivities <strong>of</strong> baicalein<br />

Bioactivities References<br />

Antioxidant activity [Chen et al., 2000; Chen et al., 2006; Zhao et al., 2000<br />

Anti-inflammatory activity [Lee et al., 2003; Suk et al., 2003; Woo et al., 2006]<br />

Anti-bacterial activity [Hahm et al., 2001]<br />

Anti-viral activity [Wu et al., 2001; Z<strong>of</strong>ia et al., 2008]<br />

Anti-cancer activity [Bonham et al., 2005; Wang et al., 2004]<br />

Free radical scavenging property [Bochorakova et al., 2003; Shao et al., 2002; Wozniak,<br />

Lamer-Zarawska & Matkowski, 2004]<br />

Inhibition <strong>of</strong> proliferation [Chang et al., 2002; Lee et al., 2005; Lin et al., 2007]<br />

Neuroprotective activity [Cheng et al., 2008; Liu et al., 2006; Liu et al., 2007]<br />

Cardioprotective effect [Woo, Cheng & Waye, 2005]<br />

Reduction <strong>of</strong> drug-induced adverse<br />

effect<br />

[Sangeeta et al., 2007]<br />

Anxiolytic-like effect [Liao, Hun & Chen, 2003]<br />

Against endotoxic effect [Cheng et al., 2007]<br />

Upregulatory activity in cell model [Deng et al., 2008]<br />

Proangiogenic activity [Cho et al., 2008]<br />

Suppression <strong>of</strong> iNOS expression [Huang et al., 2007; Kim et al., 2001; Shen et al., 2002]<br />

Antimutagenic effects [Wozniak et al.,2004]<br />

Neuroprotective effects [Cho & Lee, 2004; Piao et al., 2004; Son et al., 2004]<br />

Anticancer effects [Chung et al., 2008; Lu et al., 2008; Zhang et al., 2008]<br />

Antiinflammatory action [Enomoto et al., 2007; Lim, 2004; Wang et al., 2007]<br />

Anxiolytic effect [Hui et al., 2002; Tai et al., 2005]<br />

Anti-virus effect<br />

Apoptosis inducement effect<br />

Anticonvulsant effect [Park et al., 2007]<br />

Immunosuppressive action<br />

prevention<br />

[Blach-Olszewska et al., 2008; Guo et al., 2007; Ma et<br />

al., 2002]<br />

[Baumann et al., 2008; Himeji et al., 2007; Lee et al.,<br />

2007]<br />

[Enomoto et al., 2007]<br />

Inhibitory <strong>of</strong> ischemic brain injury [Cho & Lee, 2004]<br />

Protective effect on endotoxininduced<br />

shock<br />

[Van et al., 2001]<br />

155

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