Medicinal Plants Classification Biosynthesis and ... - Index of
Medicinal Plants Classification Biosynthesis and ... - Index of
Medicinal Plants Classification Biosynthesis and ... - Index of
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S.M.M. Vasconcelos, J.E.R. Honório Júnior, R.N.D. Cavalcante de Abreu et al.<br />
these plants. The chemical potential <strong>of</strong> living organisms is <strong>of</strong> interest to pharmaceutical<br />
industries as a source <strong>of</strong> new drugs (e.g. taxol, ephedrine), agrochemical by providing natural<br />
fungicidal <strong>and</strong> insecticide (e.g. rotenon), food industries by providing natural substances for<br />
food flavor <strong>and</strong> color (e.g. menthol, benzoic acid), <strong>and</strong> cosmetics by natural perfumes (e.g.<br />
camphor, linalol, coumarin) (Buckingham, 1993; Braz-Filho, 2007).<br />
According to Pereira (1993), there are about 12.000 known secondary metabolites,<br />
including terpenes, alkaloids, acetogenins, aromatics, <strong>and</strong> others used to intoxicate or<br />
dissuade insects or herbivore mammals <strong>of</strong> their predator action (e.g.: camphor, psoralen,<br />
florizin). Many <strong>of</strong> these insect-plant interactions cause clear evolutionary reflexes, which are<br />
responsible for different reactions that some plants present against their predators.<br />
<strong>Medicinal</strong> plants are the ones that exert pharmacologic actions when administered to men<br />
or animals in any route or preparation (Brasil, 2001). They play important role in modern<br />
medicine, because they provide extremely important drugs that could hardly be obtained by<br />
chemical synthesis, as the alkaloids <strong>of</strong> Papaver somniferum <strong>and</strong> cardiotonic glycosides <strong>of</strong><br />
Digitalis spp (Turolla, Nascimento, 2006). Although there is a clear development <strong>of</strong> huge<br />
pharmaceutical laboratories <strong>and</strong> synthetic drugs, medicinal plants remain as an alternative<br />
treatment in some parts <strong>of</strong> the world.<br />
The World Health Association (WHO), through the Traditional Medicine Program,<br />
sponsors <strong>and</strong> encourages many countries to study the potential utility <strong>of</strong> traditional medicine,<br />
including the evaluation <strong>of</strong> efficacy <strong>and</strong> security <strong>of</strong> drugs derived from medicinal plants<br />
(WHO, 1993).<br />
According to WHO estimates, a big part <strong>of</strong> the population, even in rich countries, still<br />
uses traditional medicaments, especially medicinal plants. Although it is easy to have access<br />
to modern medicine in these countries, the use <strong>of</strong> medicinal herbs remains popular for<br />
historic <strong>and</strong> cultural reasons. About 25% <strong>of</strong> all medical prescriptions have at least one<br />
product obtained from plants. On the other side, in developing countries, 65-80% <strong>of</strong> the<br />
population depends exclusively on medicinal plants for basic health care. This means that<br />
almost 4 billion <strong>of</strong> people trust in plants as sources <strong>of</strong> drugs (Agra et al., 2007; Raven et al.,<br />
2001).<br />
There are about 500 thous<strong>and</strong> species <strong>of</strong> plants in the world. Brazil is one <strong>of</strong> the 12<br />
nations that have 70% <strong>of</strong> the planet biodiversity <strong>and</strong> is the country with the biggest vegetal<br />
cover <strong>of</strong> the Earth. This fact has economic importance <strong>and</strong> also requires the conservation <strong>of</strong><br />
such biodiversity (Brasil, 2001).<br />
Nowadays, although the free <strong>of</strong>ficial health system reaches the country, it cannot<br />
provide, in an adequate manner, the dem<strong>and</strong> for health care. Furthermore, these people<br />
cannot afford health pr<strong>of</strong>essional or industrialized drugs. Thus, they use medicinal plants,<br />
which are sometimes cultivated in their garden (Pilla, Amorozo, Furlan, 2006).<br />
A great part <strong>of</strong> medicinal flora does not have its chemical <strong>and</strong> pharmacological properties<br />
well studied, <strong>and</strong> the popular knowledge about these plants exists predominantly in developing<br />
countries. The Brazilian Health Ministry has encouraged researches with traditional plants<br />
looking for possible new compounds <strong>and</strong> effects <strong>of</strong> these plants (Brasil, 2001).<br />
In Brazil, especially in Northeast, about 80% <strong>of</strong> the population has low purchasing power<br />
<strong>and</strong> finds the cure for health problems in folk medicine, most <strong>of</strong> the time using plants