Plutonium Biokinetics in Human Body A. Luciani - Kit-Bibliothek - FZK

Table 3.1.12 Testing of the Model-b using the excretion data of occupational workers. The
ratios of the value of function F for the Model-b by the value for ICRP 67 model
are presented for some occupationally exposed individuals and standard
conditions of exposure to 239 Pu.
Case
code
Number
of data
112
F(Model-b)
F(ICRP 67)
AMAD = 1 µm AMAD = 5 µm
Type M Type S Type M Type S
242 (U) 107 0.97 0.98 0.97 0.98
193 (U) 105 0.91 0.92 0.92 0.93
4 (M) 105 0.94 0.95 0.95 0.96
208 (U) 64 0.97 0.98 0.97 0.98
25 (M) 21 0.99 0.99 0.99 0.99
10 (M) 21 1.05 1.05 1.04 1.05
18 (M) 20 1.36 1.48 1.28 1.41
7 (M) 10 0.96 0.91 0.97 0.91
21 (M) 8 0.83 0.79 0.85 0.81
(U) : case from United States Uranium and Transuranium Registries
(M) : case from Manhattan Project
Although intake estimates are not the direct goal of the verification process of this
section, as they were obtained as by-product of the minimizing procedure of the function F,
they are here present and commented.
In Table 3.1.13 the intakes calculated using the Model-b are presented with the
percentage deviation from the ICRP 67 estimates for all the standard absorption types (M, S)
and AMADs (1 and 5 µm). The average deviation on all the contamination cases indicates
that for absorption type M the Model-b and ICRP 67 yield almost the same intakes, while for
absorption type S the latter model estimates intakes to be smaller by about 10 %. This follows
not only from the urinary excretion values predicted by the model, but also from the period
when the considered urine samples were collected (between 1957 and 1997, i.e. 4,400 and
19,000 days post-intake). As shown in Figure 3.1.19 in case of an aerosol of 1 μm AMAD
inhaled by a forty years old subject, type M, the Plutonium urinary excretion predicted by the
Model-b ranges between –11% and +7% of the ICRP 67 predictions in the period of the
samples collection for the considered actual cases of contamination. Therefore on the average
the final effect is that both models estimate almost the same intakes. In the same period and
under the same condition of exposure, but for absorption S, the Plutonium urinary excretion
predicted by the age related model ranges between –20% and +1% of the ICRP 67
predictions. Therefore the estimations of intake based on the Model-b are higher than the
ICRP 67 predictions.