Plutonium Biokinetics in Human Body A. Luciani - Kit-Bibliothek - FZK

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three detectors are used. Two detectors are located on both side of subject’s head: in Figure 2.3.10 they are depicted according to a lateral prospective. The third detector is located under the subject’s head and therefore not visible. Both detecting systems were calibrated, for their own measurement positions, using the whole USTUR phantom to evaluate the efficiency factors in case of activity distribution in the skeleton. Furthermore both detecting systems were calibrated using LLNL phantom to evaluate the efficiency factor in case of activity distribution in lungs, liver and lymph nodes. For such calibration issue, efficiency factors relating to different chest wall thickness were evaluated using the different overlays available for the LLNL phantom. As phoswich is even used for measurement of activity in head, efficiency factors for activity distribution in lungs, liver and lymph nodes were evaluated using the LLNL phantom to evaluate their contribution for measurements performed on head. In this case, owing to their low contributions, only a LLNL phantom overlay was used (29 mm, one of the two central values). The efficiency factors of the detecting systems for 59.5 keV energy peak of 241 Am are given in Table 2.3.3 and Table 2.3.4 under different measurements positions of detectors (MP) and activity distribution (AD) of the radionuclide in the body. For LLNL phantom efficiency factors relate to overlays with 50%/50% fat/muscle ratio. HPGe Measurement position 1 2 Figure 2.3.10 The measurement positions (MP) of HPGe and phoswich detectors in respect of the subject. 64 Phoswich Measurement position Head Lungs Liver Knee
Table 2.3.3 Efficiency factors of HPGe detecting system for 59.5 keV energy peak of 241 Am under different measurements positions (MP) and activity distribution (AD) of radionuclides using LLNL and USTUR phantoms (time of measurement, t M, 3000 and 2000 s, respectively). MP - AD Detector Efficiency factors in impulse/t M per Bq of 241 Am in the respective organ Overlays [mm] for LLNL phantom 19 25 29 36 1 - Lung D 1 1.18 0.93 0.78 0.60 D 2 1.77 1.43 1.26 0.95 D 3 1.56 1.34 1.14 0.86 D 4 0.22 0.19 0.18 0.16 1 - Liver D 1 0.06 0.05 0.05 0.04 D 2 0.19 0.15 0.14 0.11 D 3 0.47 0.41 0.37 0.31 D 4 2.29 1.88 1.51 1.12 1 – Lymph node D 1 0.61 0.49 0.43 0.33 D 2 0.94 0.75 0.66 0.49 D 3 0.46 0.37 0.32 0.25 D 4 0.04 0.04 0.03 0.03 2 - Lung D 1 1.18 0.96 0.80 0.60 D 2 1.54 1.28 1.07 0.79 D 3 0.43 0.38 0.36 0.29 D 4 0.09 0.08 0.08 0.08 2 - Liver D 1 0.06 0.06 0.06 0.05 D 2 0.17 0.15 0.16 0:11 D 3 1.70 1.41 1.49 0.92 D 4 1.67 1.36 0.91 0.88 2 – Lymph node D 1 0.42 0.34 0.29 0.27 D 2 0.61 0.50 0.43 0.35 D 3 0.06 0.06 0.05 0.06 D 4 0.03 0.03 0.02 0.03 65 USTUR phantom 1 - Skeleton D 1 0.025 D 2 0.035 D 3 0.019 D 4 0.0037 2 - Skeleton D 1 0.025 D 2 0.029 D 3 0.0029 D 4 0.0026
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Forschungszentrum Karlsruhe in der
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Für diesen Bericht behalten wir un
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i ABSTRACT The biokinetic model pre
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ZUSAMMENFASSUNG Das von der Interna
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1 INDEX OF CONTENTS INDEX OF SYMBOL
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3 INDEX OF SYMBOLS Here a short glo
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Chapter 1 Introduction 5
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the duties of the Department for Ra
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adionuclide. Therefore only isotope
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stabilise the +4 oxidation state [1
Page 24 and 25: techniques adopted in the early pha
Page 26 and 27: present in spent and MOX reactor fu
Page 28 and 29: INTRAVENOUS INJECTION skin WOUND bl
Page 30 and 31: functions, defined as retained and
Page 32 and 33: the contamination event, of such as
Page 34 and 35: Table 1.3.2 Indicative 239 Pu detec
Page 36 and 37: The kinetics of Plutonium in the ki
Page 38 and 39: 1.4.2 COMMENTS ON THE ICRP 67 MODEL
Page 41: Chapter 2 Data and measurements 31
Page 44 and 45: Therefore the radiolysis process, m
Page 46 and 47: Recent technologic developments in
Page 48 and 49: eu(t) = 0.19e −0.272t + 0.023e
Page 50 and 51: function for each of the considered
Page 52 and 53: the minimum detectable activity of
Page 54 and 55: 2.2.2 AVAILABLE MEASUREMENTS Immedi
Page 56 and 57: Table 2.2.4 Daily fecal excretion o
Page 58 and 59: elements the spectral distribution
Page 60 and 61: The phoswich detector is based on t
Page 62 and 63: HPGe crystals are produced in cylin
Page 64 and 65: This quantity is normally expressed
Page 66 and 67: The peak is located in the region B
Page 68 and 69: To introduce the second quantity, t
Page 70 and 71: 117 cm 3 h -1 for the incoming and
Page 72 and 73: Figure 2.3.8 The Lawrence Livermore
Page 76 and 77: Table 2.3.4 Efficiency factors of p
Page 78 and 79: • the necessity of performing mea
Page 80 and 81: Table 2.3.7 Impulses in the measure
Page 82 and 83: 2.4 ACTIVITY MEASUREMENTS IN BIOASS
Page 84 and 85: If more then one radionuclide is ma
Page 86 and 87: L A is the air layer in µgcm -2 ;
Page 88 and 89: The electrodeposition cell used for
Page 90 and 91: Table 2.4.1 238 Pu, 239 Pu and 241
Page 93 and 94: 3.1.1 MATHEMATICAL TOOLS 3.1.1.1 So
Page 95 and 96: calculating the amount of Plutonium
Page 97 and 98: 3.1.2 ANALYSIS OF THE ICRP 67 MODEL
Page 99 and 100: empirical curves given by Langham,
Page 101 and 102: the worst performance of the group.
Page 103 and 104: leave the total clearance from the
Page 105 and 106: Figure 3.1.4 shows that the use of
Page 107 and 108: 3.1.3 MODIFICATION OF ICRP 67 MODEL
Page 109 and 110: The structure of Polig’s skeleton
Page 111 and 112: Percentage daily urinary excretion
Page 113 and 114: of 0.693d -1 . The values of the F
Page 115 and 116: Percentage daily urinary excretion
Page 117 and 118: the basis of all the reference data
Page 119 and 120: Table 3.1.10 Transfer rates of the
Page 121 and 122: 3.1.4 VERIFICATION OF THE OPTIMIZED
Page 123 and 124: Table 3.1.13 Intakes and percentage
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soft tissue ST2 soft tissue ST0 sof
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For the routine application of Mode
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excreted by individuals aged sixty
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Table 3.1.20 Exponents and coeffici
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tract [57] to consider a contaminat
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The sensitivity coefficients for th
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Sensitivity coefficients S i Figure
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transfer rates on the Plutonium uri
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Geometric standard deviations rangi
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Percentage daily urinary excretion
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Percentage daily urinary excretion
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3.2 APPLICATION OF THE OPTIMIZED MO
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lymph nodes, as in the LLNL phantom
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Americium in the lungs [Bq] 1000 10
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Daily urinary excretion [Bqd -1 ] 1
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long time is not yet described by t
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excretion that is one of the main i
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The comparison of model’s predict
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Americium in the lungs [Bq] 1000 10
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153 CONCLUSIONS The optimized model
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Annex Quantities used in Radiologic
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present. As the radiation weighting
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w R is the radiation weighting fact
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161 BIBLIOGRAPHY 1. Plutonium. W. K
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29. Nenot, J.-C. and Stather, J. W.
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55. International Atomic Energy Age
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81. Crowley, J., Lanz, H., Scott, K
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107. Hempelmann, L.H., Langham,W.H.
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137. Breitestein, B.D., Newton, C.E
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167. Harrison, J.D., Khursheed, A.,
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JOURNALS OWN PUBLICATIONS RELATED T
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177 ACKNOWLEDGEMENTS Special thanks
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Name: Andrea Luciani Date and place
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Plutonium Biokinetics in Human Body A. Luciani - Kit-Bibliothek - FZK

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