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Plutonium Biokinetics in Human Body A. Luciani - Kit-Bibliothek - FZK

Plutonium Biokinetics in Human Body A. Luciani - Kit-Bibliothek - FZK

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to be specified at a po<strong>in</strong>t but it is normally used to express the average dose absorbed by an organ or<br />

a tissue:<br />

where ε T is the average dose absorbed by the organ or tissue of m T.<br />

156<br />

equation A.2<br />

The probability of occurrence of stochastic effects depends l<strong>in</strong>early on the absorbed dose<br />

over the low dose range. The dose response relationship is not l<strong>in</strong>ear for determ<strong>in</strong>istic effects;<br />

therefore the absorbed dose is not <strong>in</strong>dicative of the severity of such effects, unless the dose is<br />

uniformly absorbed over the organ or tissue of <strong>in</strong>terest.<br />

However the probability of stochastic effects depends not only on the absorbed dose, but<br />

also on the type and energy of the radiation caus<strong>in</strong>g deliver<strong>in</strong>g the dose to the biological matter. In<br />

order to take <strong>in</strong>to account of this effect radiation weight<strong>in</strong>g factors, w R, have been set up. The<br />

radiation weight<strong>in</strong>g factors are given <strong>in</strong> Table A.1.<br />

Table A.1 Radiation weight<strong>in</strong>g factors.<br />

D T = T<br />

m T<br />

Type and energy range Radiation weight<strong>in</strong>g factor, w R<br />

Photons, all energies 1<br />

Electrons and muons, all energies 1<br />

Neutrons, energy E n < 10 keV 5<br />

10 keV ≤ E n < 100 keV 10<br />

100 keV ≤ E n < 2 MeV 20<br />

2 MeV ≤ E n < 20 MeV 10<br />

E n ≥ 20 MeV 5<br />

Protons, other then recoil protons, energy > 2 MeV 5<br />

Alpha particles, fission fragments, heavy nuclei 20<br />

The absorbed dose weighted by the radiation weight<strong>in</strong>g factors is called equivalent dose and<br />

it is expressed as follow<strong>in</strong>g:<br />

HT = ∑wR<br />

DT , R<br />

R<br />

equation A.3<br />

where D T,R is the absorbed dose averaged over a tissue or organ T due to the radiation R and<br />

w R is the relat<strong>in</strong>g radiation weight<strong>in</strong>g factor. The summation is <strong>in</strong>troduced <strong>in</strong> order to account of a<br />

radiation field where particles of types and energy with different radiation weight<strong>in</strong>g factors are

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