Plutonium Biokinetics in Human Body A. Luciani - Kit-Bibliothek - FZK

More documents

Recommendations

Info

68. Council Directive 96/29/Euratom of 13 May 1996 laying down basic safety standards for the protection of the health of workers and the general public against the dangers arising from ionizing radiation. Official Journal of the European Communities, Vol. 39, 29 June 1996. 69. Hurtgen, C. Bioassay techniques for the analysis of excreta. In the Proceedings of Assessments of doses from occupational intakes of radionuclides, 6 – 10 October 1997, Mol, Belgium, 1997 70. Boecker, B., Hall, R., Inn, K., Lawrence, J., Ziemer, P., Eisele, G., Wachholz, B. and Burr, W. Current status of bioassay procedures to detect and quantify previous exposure to radioactive material. Health. Phys. 60, Suppl. 1: 45-100, 1991. 71. Moorthy, A. R., Schopfer, C. J. and Bannerjec, S. Plutonium from atmospheric weapons testing: fission track analysis of urine samples. Anal. Chem. 60:857-860, 1988. 72. Wrenn, M. E., Singh, N. P. and Xue, Y. H. Urinary excretion of 239Pu by the general population: measurement techniques and results. Rad. Prot. Dosim. 53(1-4):81-84, 1994. 73. Wyse, E.T. and Fisher, D. R. Radionuclide bioassay by inductively couples plasma mass spectrometry (ICP-MS). Rad. Prot. Dosim. 55(3):199-206, 1994. 74. International Commission on Radiological Protection. Age-dependent doses to members of the public from intake of radionuclides: Part 2 Ingestion dose coefficients. ICRP Publication 67. Pergamon Press, Oxford; Ann. ICRP 23(3/4); 1993. 75. International Commission on Radiological Protection. Age-dependent doses to members of the public from intake of radionuclides: Part 1. ICRP Publication 56. Pergamon Press, Oxford; Ann. ICRP 20(2); 1989. 76. Leggett, R.W. A retention-excretion model for americium in humans. Health Phys. 62:288-310; 1992. 77. Leggett, R.W., Bouville, A. and Eckermann, K.F. Reliability of the ICRP’s systemic biokinetic models. Radiat. Prot. Dosim. 79(1-4):335-342. 78. Taylor, D.M., Lehman, F., Planas-Bohne, F. and Seidel, F. The metabolism of radiohafnium in rats and hamsters: a possible analog of plutonium for metabolic studies. Radiat. Res. 95:339-358, 1983. 79. Popplewell, D.S. Biokinetics and absorption of actinides in human volunteers: A review. Appl. Radiat. Isot. 46(5):279-286, 1995. 80. Langham, W.R., Bassett, S.H., Harris, P.S. and Carter, R.E. Distribution and excretion of plutonium administered intraveneusly to man. Los Alamos Scientific Laboratory; LASL Report LA-1151; 20 September 1950. Reprinted in Health Phys. 38(June):1031- 1060, 1980. 166
81. Crowley, J., Lanz, H., Scott, K. and Hamilton, J.H. A comparison of the metabolism of plutonium (238Pu) in man and the rat. Argonne National Laboratory, Argonne, Illinois, Report CH-3589, 1946. 82. Russell, E. R. and Nickson, J. J. The distribution and excretion of plutonium in two human subjects. Argonne National Laboratory, Argonne, Illinois, Report CH-3607, 1946. 83. Nickson, J.J. and Rose, J. E. Report for month of January 1946. Medical Industrial Hazards Section, Metallurgical Laboratory, University of Chicago, Report MUC-HG- 1187, 1946. 84. Nickson, J.J. and Rose, J. E. Report for month of February 1946. Medical Industrial Hazards Section, Metallurgical Laboratory, University of Chicago, Report MUC-HG- 1184, 1946. 85. Nickson, J.J. and Rose, J. E. Report for month of March & April 1946. Medical Industrial Hazards Section, Metallurgical Laboratory, University of Chicago, Report MUC-HG-1203, 1946. 86. Russell, E. R. Report for month of May 1946. Biochemical Survey Section, Metallurgical Laboratory, University of Chicago, Report MUC-ERR-206, 1946. 87. Russell, E. R. Report for month of June 1946. Biochemical Survey Section, Metallurgical Laboratory, University of Chicago, Report MUC-ERR-211, 1946. 88. Rundo, J., Starzyk, P.M. and Sedlet, J. The excretion rate and retention of plutonium 10,000 days after acquisition. In the Proceedings of IAEA International seminar on diagnosis and treatment of incorporated radionuclides, 8 December 1975, Vienna, International Atomic Energy Agency (IAEA), 15-22, 1976. 89. Rundo, J., Starzyk, P.M., Sedlet, J., Larsen, R.P., Oldham, R.D. and Robinson, J.J. Plutonium in the excreta of three subjects 104 days after injection. Argonne National Laboratory, Radiological and Environmental Research Division Annual Report, July 1973 – June 1974, Report ANL-75-3, 136-141, 1974. 90. Rundo, J., Larsen, R.P. and Ilcewicz, F.H. Plutonium in the blood of two subjects 104 days after injection. Argonne National Laboratory, Radiological and Environmental Research Division Annual Report, July 1974 – June 1975, Report ANL-75-60, 86-88, 1975. 91. Rundo, J., Starzyk, P.M., Larsen, R.P., Oldham, R.D., Sedlet, J. and Robinson, J.J. The excretion rate and retention of plutonium 104 days after injection. Argonne National Laboratory, Radiological and Environmental Research Division Annual Report, July 1974 – June 1975, Report ANL-75-60, 89-91, 1975. 92. Rundo, J. and Ilcewicz, F.H. Plutonium content and excretory plasma clearance of plutonium 104 days after injection. Argonne National Laboratory, Radiological and Environmental Research Division Annual Report, July 1977 – June 1978, Report ANL- 78-65, 142-144, 1978. 167
Page 1:
Forschungszentrum Karlsruhe in der
Page 4 and 5:
Für diesen Bericht behalten wir un
Page 7 and 8:
i ABSTRACT The biokinetic model pre
Page 9 and 10:
ZUSAMMENFASSUNG Das von der Interna
Page 11 and 12:
1 INDEX OF CONTENTS INDEX OF SYMBOL
Page 13 and 14:
3 INDEX OF SYMBOLS Here a short glo
Page 15:
Chapter 1 Introduction 5
Page 18 and 19:
the duties of the Department for Ra
Page 20 and 21:
adionuclide. Therefore only isotope
Page 22 and 23:
stabilise the +4 oxidation state [1
Page 24 and 25:
techniques adopted in the early pha
Page 26 and 27:
present in spent and MOX reactor fu
Page 28 and 29:
INTRAVENOUS INJECTION skin WOUND bl
Page 30 and 31:
functions, defined as retained and
Page 32 and 33:
the contamination event, of such as
Page 34 and 35:
Table 1.3.2 Indicative 239 Pu detec
Page 36 and 37:
The kinetics of Plutonium in the ki
Page 38 and 39:
1.4.2 COMMENTS ON THE ICRP 67 MODEL
Page 41:
Chapter 2 Data and measurements 31
Page 44 and 45:
Therefore the radiolysis process, m
Page 46 and 47:
Recent technologic developments in
Page 48 and 49:
eu(t) = 0.19e −0.272t + 0.023e
Page 50 and 51:
function for each of the considered
Page 52 and 53:
the minimum detectable activity of
Page 54 and 55:
2.2.2 AVAILABLE MEASUREMENTS Immedi
Page 56 and 57:
Table 2.2.4 Daily fecal excretion o
Page 58 and 59:
elements the spectral distribution
Page 60 and 61:
The phoswich detector is based on t
Page 62 and 63:
HPGe crystals are produced in cylin
Page 64 and 65:
This quantity is normally expressed
Page 66 and 67:
The peak is located in the region B
Page 68 and 69:
To introduce the second quantity, t
Page 70 and 71:
117 cm 3 h -1 for the incoming and
Page 72 and 73:
Figure 2.3.8 The Lawrence Livermore
Page 74 and 75:
three detectors are used. Two detec
Page 76 and 77:
Table 2.3.4 Efficiency factors of p
Page 78 and 79:
• the necessity of performing mea
Page 80 and 81:
Table 2.3.7 Impulses in the measure
Page 82 and 83:
2.4 ACTIVITY MEASUREMENTS IN BIOASS
Page 84 and 85:
If more then one radionuclide is ma
Page 86 and 87:
L A is the air layer in µgcm -2 ;
Page 88 and 89:
The electrodeposition cell used for
Page 90 and 91:
Table 2.4.1 238 Pu, 239 Pu and 241
Page 93 and 94:
3.1.1 MATHEMATICAL TOOLS 3.1.1.1 So
Page 95 and 96:
calculating the amount of Plutonium
Page 97 and 98:
3.1.2 ANALYSIS OF THE ICRP 67 MODEL
Page 99 and 100:
empirical curves given by Langham,
Page 101 and 102:
the worst performance of the group.
Page 103 and 104:
leave the total clearance from the
Page 105 and 106:
Figure 3.1.4 shows that the use of
Page 107 and 108:
3.1.3 MODIFICATION OF ICRP 67 MODEL
Page 109 and 110:
The structure of Polig’s skeleton
Page 111 and 112:
Percentage daily urinary excretion
Page 113 and 114:
of 0.693d -1 . The values of the F
Page 115 and 116:
Percentage daily urinary excretion
Page 117 and 118:
the basis of all the reference data
Page 119 and 120:
Table 3.1.10 Transfer rates of the
Page 121 and 122:
3.1.4 VERIFICATION OF THE OPTIMIZED
Page 123 and 124:
Table 3.1.13 Intakes and percentage
Page 125 and 126: soft tissue ST2 soft tissue ST0 sof
Page 127 and 128: For the routine application of Mode
Page 129 and 130: excreted by individuals aged sixty
Page 131 and 132: Table 3.1.20 Exponents and coeffici
Page 133 and 134: tract [57] to consider a contaminat
Page 135 and 136: The sensitivity coefficients for th
Page 137 and 138: Sensitivity coefficients S i Figure
Page 139 and 140: transfer rates on the Plutonium uri
Page 141 and 142: Geometric standard deviations rangi
Page 143 and 144: Percentage daily urinary excretion
Page 145 and 146: Percentage daily urinary excretion
Page 147 and 148: 3.2 APPLICATION OF THE OPTIMIZED MO
Page 149 and 150: lymph nodes, as in the LLNL phantom
Page 151 and 152: Americium in the lungs [Bq] 1000 10
Page 153 and 154: Daily urinary excretion [Bqd -1 ] 1
Page 155 and 156: long time is not yet described by t
Page 157 and 158: excretion that is one of the main i
Page 159 and 160: The comparison of model’s predict
Page 161 and 162: Americium in the lungs [Bq] 1000 10
Page 163 and 164: 153 CONCLUSIONS The optimized model
Page 165 and 166: Annex Quantities used in Radiologic
Page 167 and 168: present. As the radiation weighting
Page 169 and 170: w R is the radiation weighting fact
Page 171 and 172: 161 BIBLIOGRAPHY 1. Plutonium. W. K
Page 173 and 174: 29. Nenot, J.-C. and Stather, J. W.
Page 175: 55. International Atomic Energy Age
Page 179 and 180: 107. Hempelmann, L.H., Langham,W.H.
Page 181 and 182: 137. Breitestein, B.D., Newton, C.E
Page 183 and 184: 167. Harrison, J.D., Khursheed, A.,
Page 185 and 186: JOURNALS OWN PUBLICATIONS RELATED T
Page 187 and 188: 177 ACKNOWLEDGEMENTS Special thanks
Page 189 and 190: Name: Andrea Luciani Date and place
show all

Plutonium Biokinetics in Human Body A. Luciani - Kit-Bibliothek - FZK

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?