Plutonium Biokinetics in Human Body A. Luciani - Kit-Bibliothek - FZK

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152. Stephen Wolfram, The Mathematica Book. Fourth Edition. Wolfram Media/Cambridge University Press, 1999. 153. Beach, S.A., Dolphin, G.W., Duncan, K.P. and Dunster, H.J. A basis for routine urine sampling of workers exposed to Plutonium 239. Health Phys. 12(July):1671-1682; 1966. 154. Luciani, A. and Polig E. Verification and modification of the ICRP67 model for plutonium dose calculation. Health Phys. 78(3):303-310; 2000. 155. International Commission on Radiological Protection. Basic anatomical and physiological data for use in Radiological Protection: The Skeleton. ICRP Publication 70. Pergamon Press, Oxford; Ann. ICRP 25(2); 1995. 156. Luciani, A. Ein optimiertes biokinetisches Modell für Plutonium. Forschungszentrum Karlsruhe, Jahresbericht 1998 der Haptabteilung Sichereit, FZKA 6230; 1999. 157. Polig, E. Labels of surface-seeking radionuclides in the human skeleton. Health Phys. 72(1): 19-33; 1997. 158. Thomas, R.G., Healy, J.W. and McInroy, J.F. Plutonium partitioning among internal organs. Health Phys. 46(April):839-844; 1984. 159. Kathren, R.L. McInroy, J.F., Reichert, M.M. and Swint, M.J. Paritioning of Pu238, Pu239 and Am241 in skeleton and liver of U.S. Transuranium Registry autopsy cases. Health Phys. 54(February):181-188, 1988. 160. McInroy, J.F., Kathren, R.L. and Swint, M.J. Distribution of Plutonium and Americium in whole bodies donated to the United States Transuranium Registry. Radiat. Prot. Dos. 26(1/4):151-158; 1989. 161. Popplewell, D.S. and Ham, G.J. Distribution of Plutonium and Americium in tissues from a human autopsy case. J. Radiol. Pro. 9(3):159-164, 1989. 162. International Commission on Radiological Protection. Annual limits of intake of radionuclides by workers based on the 1990 Recommendations. ICRP Publication 61. Pergamon Press, Oxford; Ann. ICRP 21(4); 1991. 163. Luciani, A. Plutonium dose assessments based on a new model derived from ICRP 67. Health Phys. 80(6):618-619; 2001. 164. Luciani, A., Doerfel, H. and Polig, E. Sensitivity analysis of the urinary excretion of Plutonium. Radiat. Prot. Dosim. 93(2):179-183; 2001. 165. Hamby, D.M. A comparison of sensitivity analysis techniques. Health Phys. 68(2):195-204; 1995. 166. Khursheed, A. and Fell, T.P. Sensitivity analysis for the ICRP Publication 67 biokinetic model for Plutonium. Radiat. Prot. Dos. 74(1/2):63-73; 1997. 172
167. Harrison, J.D., Khursheed, A., Phipps, A.W., Goosses, L., Kraan, B. and Harper, F. Uncertainties in biokinetic parameters and dose coefficients determined by expert judgement. Radiat. Prot. Dosim. 79(1-4):355-358; 1998. 168. McKay, M.D., Conover, W.J. and Beckman, R.J. A comparison of the three methods for selecting values of input variables in the analysis of output from a computer code. Technometrics, 21:239-245; 1979. 169. Helton, J.C. Uncertainty and sensitivity analysis techniques for use in performance assessment for radioactive waste disposal. Reliability Engineering and System Safety, 42:327-367; 1993. 170. Khatib-Rahbar, M., Cazzoli, E., Lee, M., Nourbakhsh, H., Davis, R. and Schmidt, E. A probabilistic approach to quantifying uncertainties in the progression of severe accidents. Nuclear Science and Engineering, 102:219-259; 1989. 171. Iman, R. and Helton, J. A comparison of uncertainty and sensitivity analysis techniques for computer codes. NUREG/CR-3904, United States Nuclear Regulatory Commission; 1985. 172. Armitage, P. and Berry, G. Statistical methods in medical research. Second Edition. Blackwell Scientific Publications, Oxford, 1987. 173. International Commission on Radiological Protection. Age-dependent doses to members of the Public from intake of radionuclides: Part 4 Inhalation Dose Coefficients. Oxford: Pergamon Press; ICRP Publication 71, Ann. ICRP 25(3-4); 1996. 174. Luciani, A., Polig, E., Doerfel, H. An age-related model derived from ICRP 67 model for Plutonium dose assessments: application to an updated case of contamination. Oral Presentation at the 8th International Conference on Low level measurements of actinides and long-lived radionuclides in biological and environmental samples, Oarai, Japan, 16-20 October 2000, Proceedings of the Conference, Journal of Radioanalytical and Nuclear Chemistry 252(2):301-307, 2002. 175. National Council on Radiation protection and Measurments. Evaluating the reliability of biokinetic and dosimetric models and parameters used to assess individual doses for risk assessment purposes. NCRP Commentary N. 5, NCRP Publications, Bethesda, MD, USA, 1998. 176. Leggett, R.W. Reliability of the ICRP’s dose coefficients for members of the public. 1. Sources of uncertainty in the biokinetic models. Rad. Prot. Dosim. 95(3):199-213, 2001. 173
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Forschungszentrum Karlsruhe in der
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Für diesen Bericht behalten wir un
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i ABSTRACT The biokinetic model pre
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ZUSAMMENFASSUNG Das von der Interna
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1 INDEX OF CONTENTS INDEX OF SYMBOL
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3 INDEX OF SYMBOLS Here a short glo
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Chapter 1 Introduction 5
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the duties of the Department for Ra
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adionuclide. Therefore only isotope
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stabilise the +4 oxidation state [1
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techniques adopted in the early pha
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present in spent and MOX reactor fu
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INTRAVENOUS INJECTION skin WOUND bl
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functions, defined as retained and
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the contamination event, of such as
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Table 1.3.2 Indicative 239 Pu detec
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The kinetics of Plutonium in the ki
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1.4.2 COMMENTS ON THE ICRP 67 MODEL
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Chapter 2 Data and measurements 31
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Therefore the radiolysis process, m
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Recent technologic developments in
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eu(t) = 0.19e −0.272t + 0.023e
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function for each of the considered
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the minimum detectable activity of
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2.2.2 AVAILABLE MEASUREMENTS Immedi
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Table 2.2.4 Daily fecal excretion o
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elements the spectral distribution
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The phoswich detector is based on t
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HPGe crystals are produced in cylin
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This quantity is normally expressed
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The peak is located in the region B
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To introduce the second quantity, t
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117 cm 3 h -1 for the incoming and
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Figure 2.3.8 The Lawrence Livermore
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three detectors are used. Two detec
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Table 2.3.4 Efficiency factors of p
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• the necessity of performing mea
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Table 2.3.7 Impulses in the measure
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2.4 ACTIVITY MEASUREMENTS IN BIOASS
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If more then one radionuclide is ma
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L A is the air layer in µgcm -2 ;
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The electrodeposition cell used for
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Table 2.4.1 238 Pu, 239 Pu and 241
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3.1.1 MATHEMATICAL TOOLS 3.1.1.1 So
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calculating the amount of Plutonium
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3.1.2 ANALYSIS OF THE ICRP 67 MODEL
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empirical curves given by Langham,
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the worst performance of the group.
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leave the total clearance from the
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Figure 3.1.4 shows that the use of
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3.1.3 MODIFICATION OF ICRP 67 MODEL
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The structure of Polig’s skeleton
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Percentage daily urinary excretion
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of 0.693d -1 . The values of the F
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Percentage daily urinary excretion
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the basis of all the reference data
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Table 3.1.10 Transfer rates of the
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3.1.4 VERIFICATION OF THE OPTIMIZED
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Table 3.1.13 Intakes and percentage
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soft tissue ST2 soft tissue ST0 sof
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For the routine application of Mode
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excreted by individuals aged sixty
Page 131 and 132: Table 3.1.20 Exponents and coeffici
Page 133 and 134: tract [57] to consider a contaminat
Page 135 and 136: The sensitivity coefficients for th
Page 137 and 138: Sensitivity coefficients S i Figure
Page 139 and 140: transfer rates on the Plutonium uri
Page 141 and 142: Geometric standard deviations rangi
Page 143 and 144: Percentage daily urinary excretion
Page 145 and 146: Percentage daily urinary excretion
Page 147 and 148: 3.2 APPLICATION OF THE OPTIMIZED MO
Page 149 and 150: lymph nodes, as in the LLNL phantom
Page 151 and 152: Americium in the lungs [Bq] 1000 10
Page 153 and 154: Daily urinary excretion [Bqd -1 ] 1
Page 155 and 156: long time is not yet described by t
Page 157 and 158: excretion that is one of the main i
Page 159 and 160: The comparison of model’s predict
Page 161 and 162: Americium in the lungs [Bq] 1000 10
Page 163 and 164: 153 CONCLUSIONS The optimized model
Page 165 and 166: Annex Quantities used in Radiologic
Page 167 and 168: present. As the radiation weighting
Page 169 and 170: w R is the radiation weighting fact
Page 171 and 172: 161 BIBLIOGRAPHY 1. Plutonium. W. K
Page 173 and 174: 29. Nenot, J.-C. and Stather, J. W.
Page 175 and 176: 55. International Atomic Energy Age
Page 177 and 178: 81. Crowley, J., Lanz, H., Scott, K
Page 179 and 180: 107. Hempelmann, L.H., Langham,W.H.
Page 181: 137. Breitestein, B.D., Newton, C.E
Page 185 and 186: JOURNALS OWN PUBLICATIONS RELATED T
Page 187 and 188: 177 ACKNOWLEDGEMENTS Special thanks
Page 189 and 190: Name: Andrea Luciani Date and place
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