OP-II-3

DEVELOPING MICROFLUIDIC DEVICE WITH EMBEDDEDNANOSTRUCTURES FOR IN-SITU RAMAN OPERANDOSPECTROSCOPYVictor Sans 1 , Vladimir Kozhevin 2,3 , Denis Yavsin 2,3 , Igor Kuzmin 2 ,Sergey Gurevich 2,3 , Alexei Lapkin 1PP-III-621 School of Engineering, University of Warwick, United Kingdom,V.Sans.Sangorrin@warwick.ac.uk2 INCATTECH LLC, St. Petersburg, Russia3 Ioffe Physical Technical Institute, Russian Academy of Sciences, RussiaMicrofluidic devices have gained importance over the last years in chemicalsynthesis, biological and analytical applications.[1-3] The coupling of microfluidicdevices with in-situ spectroscopic techniques capable to provide analyticalinformation about the reaction media opens a new whole set of opportunities to studyand optimise chemical kinetics, reaction mechanisms, thermodynamic properties ofinterest, etc.[4-5] The simultaneous spectroscopic characterization of a catalyticmaterial during the reaction and the measurement of its catalytic activity/selectivityhas been coined as Operando Spectroscopy.[6]Herein, we report on the application of laser electrodispersion (LE) to depositamorphous gold nanoparticles (AuNPs) with a narrow size distribution on the Si andSiO x surfaces (Figure 1). The particles were deposited on etched and oxidized Siwafers and studied by TEM, SEM and XPS. Their application in surface enhancedRaman spectroscopy (SERS) is described using methylene blue and crystal violet astarget molecules (Figure 2). The AuNPs proved to be efficient to detect very lowconcentrations of analytes (10 –8 M).Figure 1. TEM image corresponding to AuNPs deposited by laser electrodeposition.553