The Clinical Guide to Supportive and Palliative Care for HIV/AIDS

A Clinical Guide to Supportive and Palliative Care for HIV/AIDS • Chapter 4: PainTable 4-8: Psychotropic Adjuvant Analgesic Drugs for HIV/AIDS PainApproximateDaily DosageGeneric Name26 picasRange (MG) RouteTRICYCLIC ANTIDEPRESSANTSAmitriptyline 10-150 PO, IMNortriptyline 10-150 POImipramine 15.5-150 PO, IMDesipramine 10-150 POClomipramine 10-150 PODoxepin 12-150 PO, IMHETEROCYCLIC AND NON-CYCLIC ANTIDEPRESSANTSTrazodone 125-300 POMaprotiline 50-300 POSEROTONIN REUPTAKE INHIBITORSFluoxetine 20-80 POParoxetine 10-60 POSertraline 50-200 PONEWER AGENTSNefazodone 100-500 POVenlafaxine 75-300 POPSYCHOSTIMULANTSMethylphenidate 2.5-20 bid PODextroamphetamine 2.5-20 bid POPemoline 13.75-75 bid POModafinil 100-400 POPHENOTHIAZINESFluphenazine 1-3 PO, IMMethotrimeprazine 10-20 q6h IM, IVBUTYROPHENONESHaloperidol 1-3 tid PO, IVPimozide 2-6 bid POANTIHISTAMINESHydroxyzine 50 q4h -q6h POANTICONVULSANTSCarbamazepine 200 tid - 400 tid POPhenytoin 300-400 POValproate 500 tid - 1000 tid POGabapentin 300 tid - 1000 tid POORAL LOCAL ANESTHETICSMexiletine 600-900 POCORTICOSTEROIDSDexamethasone 4-16 PO, IVBENZODIAZEPINESAlprazolam 0.25-2.0 tid POClonazepam 0.5-4 bid POPO=per oral; IM=intramuscular; IV=intravenous; q6h=every 6 hoursbid = twice a day, tid = three times a day, qid = four times a day110U.S. Department of Health and Human Services • Health Resources and Services Administration • HIV/AIDS Bureau