The Clinical Guide to Supportive and Palliative Care for HIV/AIDS

More documents

Recommendations

Info

A Clinical Guide to Supportive and Palliative Care for HIV/AIDS • Chapter 27: Pharmacologic Interactions of Clinical SignificanceTable 27-12:Summary of Significant Drug-Drug Interactionsin Palliative Care of HIV Disease (continued)Disease Statesand MedicationsAntabuseProtease InhibitorsRitonavir Indinavir Nelfinavir(Norvir) (Crixivan) (Viracept)Causes an intenseflushing &abdominal pain dueto alcohol in ARTCauses an antabuselikeeffect withmetronidazole whengiven with alcoholOral Contraceptives↓ plasma conc. ofethinyl estradiol↓ plasma conc. ofethinyl estradiolSildenafil (Viagra)Significantly ↑plasma conc. ofdrug due to a ↓ inits clearance ∴results in ↑ effectsSignificantly ↑plasma conc. ofdrug due to a ↓ inits clearance ∴results in ↑ effectsSignificantly ↑plasma conc. ofdrug due to a ↓ inits clearance ∴results in ↑ effectsHERBAL REMEDIESSt. John’s Wort*GarlicCauses severegastrointestinaltoxicity↓ plasma conc. ofPIs by more than50%*This herbal product with PIs will increase the risk of viral resistance.ILLEGAL DRUGSEcstasySlows down theliver enzymes thatbreak down thedrug ∴ becomes 5-10 times strongerMost dangerousinteractionAvoid in patients with family or personal history of depressionor anxiety disorders because the drug damages the serotoninneurons.MarijuanaProtease inhibitors increase the levels of THC (activeingredient) ∴ smaller doses may have a greater effect576U.S. Department of Health and Human Services • Health Resources and Services Administration • HIV/AIDS Bureau
A Clinical Guide to Supportive and Palliative Care for HIV/AIDS • Chapter 27: Pharmacologic Interactions of Clinical SignificanceTable 27-12:Heroin26 picasDisease Statesand MedicationsSummary of Significant Drug-Drug Interactionsin Palliative Care of HIV Disease (continued)Protease InhibitorsRitonavir Indinavir Nelfinavir(Norvir) (Crixivan) (Viracept)↓ plasma conc. of by50% ∴ ↓ risk ofoverdoseKetamine (Special K)AmphetaminesCauses “chemicalhepatitis”↑ levels in the bloodby 20%-30%Strengthens orweakens the effectsof ritalinLSDCocaineDISEASE Disease STATES Statesand and Medications MedicationsCARDIOVASCULARAntiarrhythmiasNo knowninteractionsNo knowninteractionsNo knowninteractionsDoubles the speed at which the virus reproduces ∴ increasesprogression of the diseaseProtease PROTEASE INHIBITORSInhibitorsAgeneraseSaquinavir(Amprenavir)(Fortovase)↑ plasma conc. of amiodarone& quinidine↑ plasma conc. of lidocaineCa ++ ChannelBlockers↑ plasma conc. of nifedipine(Significant ↑ over allCa ++ Channel Blockers)AnithyperlipidemicsGASTROINTESTINALSignificant ↑ in levels ofsimvastatin & lovastatinCisapride↑ in plasma conc. ∴ results inserious or life-threateningarrhythmias(No longer on market)↑ in plasma conc. ∴ results inserious or life-threateningarrhythmias(No longer on market)RESPIRATORYAstemizole andterfenadine↑ in plasma conc. ∴ results inserious or life-threateningarrhythmias↑ in plasma conc. ∴ results inserious or life-threateningarrhythmiasXXVIIU.S. Department of Health and Human Services • Health Resources and Services Administration • HIV/AIDS Bureau 577
Page 4 and 5:
DedicationA Clinical Guide to Suppo
Page 6 and 7:
Lynn A Jansen, RN, PhDAssistant Res
Page 9 and 10:
TABLE OF CONTENTSPart IChapter 1Cha
Page 11 and 12:
IChapter 1.26 picasHIV and Palliati
Page 13:
IA Clinical Guide to Supportive and
Page 16 and 17:
A Clinical Guide to Supportive and
Page 18 and 19:
Page 20 and 21:
Page 22 and 23:
Page 24 and 25:
Page 26 and 27:
Page 28 and 29:
Page 30 and 31:
Page 32 and 33:
Page 34 and 35:
Page 36 and 37:
Page 38 and 39:
Page 40 and 41:
Page 42 and 43:
Page 44 and 45:
Page 47 and 48:
IIIChapter 3.Assessment of Physical
Page 49 and 50:
Page 51 and 52:
Page 53 and 54:
Page 55 and 56:
Page 57 and 58:
Page 59 and 60:
Page 61 and 62:
Page 63 and 64:
Page 65 and 66:
Page 67 and 68:
Page 69 and 70:
Page 71 and 72:
Page 73 and 74:
Page 75 and 76:
Page 77 and 78:
Page 79 and 80:
Page 81 and 82:
Page 83 and 84:
Page 85 and 86:
Page 87 and 88:
Page 89 and 90:
Page 91 and 92:
Page 93:
Page 96 and 97:
Page 98 and 99:
Page 100 and 101:
Page 102 and 103:
Page 104 and 105:
Page 106 and 107:
Page 108 and 109:
Page 110 and 111:
Page 112 and 113:
Page 114 and 115:
Page 116 and 117:
Page 118 and 119:
Page 120 and 121:
Page 122 and 123:
Page 124 and 125:
Page 126 and 127:
Page 128 and 129:
Page 130 and 131:
Page 132 and 133:
Page 134 and 135:
Page 136 and 137:
Page 138 and 139:
Page 140 and 141:
Page 142 and 143:
Page 145 and 146:
Chapter 6.26 picasPulmonary Symptom
Page 147 and 148:
Page 149 and 150:
Page 151 and 152:
Page 153 and 154:
Page 155 and 156:
Page 157 and 158:
Page 159 and 160:
Page 161 and 162:
Page 163 and 164:
Page 165:
Page 168 and 169:
Page 170 and 171:
Page 172 and 173:
Page 174 and 175:
Page 177 and 178:
Chapter 8.26 picasOral ProblemsDavi
Page 179 and 180:
Page 181 and 182:
Page 183 and 184:
Page 185 and 186:
Page 187 and 188:
Chapter 9.26 picasDermatologic Prob
Page 189 and 190:
Page 191 and 192:
Page 193 and 194:
Page 195 and 196:
Page 197 and 198:
Page 199 and 200:
Page 201 and 202:
Page 203 and 204:
Page 205 and 206:
Page 207 and 208:
Page 209 and 210:
Page 211 and 212:
Page 213 and 214:
Page 215 and 216:
Page 217 and 218:
Chapter 10.26 picasPsychiatric Prob
Page 219 and 220:
Page 221 and 222:
Page 223 and 224:
Page 225 and 226:
Page 227 and 228:
Page 229 and 230:
Page 231 and 232:
Page 233 and 234:
Page 235 and 236:
Page 237 and 238:
Page 239 and 240:
Page 241 and 242:
Page 243 and 244:
Page 245 and 246:
Page 247 and 248:
Page 249 and 250:
Page 251 and 252:
Page 253 and 254:
Page 255 and 256:
Page 257 and 258:
Page 259 and 260:
Page 261 and 262:
Page 263 and 264:
Chapter 11.26 picas Substance Use P
Page 265 and 266:
Page 267 and 268:
Page 269 and 270:
Page 271 and 272:
Page 273 and 274:
Page 275:
Page 278 and 279:
Page 280 and 281:
Page 282 and 283:
Page 284 and 285:
Page 286 and 287:
Page 288 and 289:
Page 290 and 291:
Page 292 and 293:
Page 294 and 295:
Page 296 and 297:
Page 298 and 299:
Page 300 and 301:
Page 302 and 303:
Page 304 and 305:
Page 306 and 307:
Page 308 and 309:
Page 311 and 312:
Chapter 14.26 picasCulture and Care
Page 313 and 314:
Page 315 and 316:
Page 317 and 318:
Page 319 and 320:
Page 321 and 322:
Page 323 and 324:
Page 325 and 326:
Chapter 15.26 picasSpecial Populati
Page 327 and 328:
Page 329 and 330:
Page 331 and 332:
Page 333 and 334:
Page 335 and 336:
Page 337:
Page 340 and 341:
Page 342 and 343:
Page 344 and 345:
Page 346 and 347:
Page 348 and 349:
Page 350 and 351:
Page 352 and 353:
Page 354 and 355:
Page 356 and 357:
Page 359 and 360:
Chapter 17.26 picasEthical IssuesLy
Page 361 and 362:
Page 363 and 364:
Page 365 and 366:
Page 367 and 368:
Page 369 and 370:
Page 371 and 372:
Page 373 and 374:
Page 375 and 376:
Chapter 18.26 picasLegal and Financ
Page 377 and 378:
Page 379 and 380:
Page 381 and 382:
Page 383 and 384:
Page 385 and 386:
Page 387 and 388:
Page 389 and 390:
Page 391 and 392:
Page 393 and 394:
Page 395 and 396:
Page 397 and 398:
Chapter 19.Palliative 26 picas Care
Page 399 and 400:
Page 401 and 402:
Page 403 and 404:
Page 405 and 406:
Page 407 and 408:
Page 409 and 410:
Page 411 and 412:
Page 413 and 414:
Page 415 and 416:
Page 417:
Page 420 and 421:
Page 422 and 423:
Page 424 and 425:
Page 426 and 427:
Page 428 and 429:
Page 430 and 431:
Page 432 and 433:
Page 434 and 435:
Page 436 and 437:
Page 438 and 439:
Page 441 and 442:
Chapter 21.26 picas Patient-Clinici
Page 443 and 444:
Page 445 and 446:
Page 447 and 448:
Page 449 and 450:
Page 451 and 452:
Page 453 and 454:
Page 455:
Page 458 and 459:
Page 460 and 461:
Page 462 and 463:
Page 464 and 465:
Page 466 and 467:
Page 468 and 469:
Page 470 and 471:
Page 472 and 473:
Page 474 and 475:
Page 476 and 477:
Page 478 and 479:
Page 480 and 481:
Page 482 and 483:
Page 484 and 485:
Page 486 and 487:
Page 489 and 490:
Chapter 23.26 picas Medical Care in
Page 491 and 492:
Page 493 and 494:
Page 495 and 496:
Page 497 and 498:
Page 499 and 500:
Page 501:
Page 504 and 505:
Page 506 and 507:
Page 508 and 509:
Page 510 and 511:
Page 512 and 513:
Page 515 and 516:
Chapter 25.26 picas Prevention of S
Page 517 and 518:
Page 519 and 520:
Page 521 and 522:
Page 523 and 524:
Page 525 and 526:
Chapter 26.26 picasResourcesMagda B
Page 527 and 528:
Page 529 and 530:
Page 531 and 532:
Page 533 and 534:
Page 535 and 536: A Clinical Guide to Supportive and
Page 557: A Clinical Guide to Supportive and
Page 606 and 607: DRUGS AND THERAPIES INDEXNOTES: Ent
Page 612: A Clinical Guide to Supportive and
show all

The Clinical Guide to Supportive and Palliative Care for HIV/AIDS

Create successful ePaper yourself

Delete template?

Save as template?