Development of Karl Fischer Reagents

Chapter I: Basic Knowledge
a) No esterification reaction during normal titration.
b) Since methanol can be used as the titration solvent, Karl Fischer titration
yields good results.
c) Salicylic acid has a low moisture content.
The fact that salicylic acid is a solid, is a drawback. However, preparation
simply involves the measurement of about 10g of salicylic acid into a titration
flask and the addition of 50ml of Dehydrated Solvent GEX (or MS), then
stirring until dissolved. Up to 70mmol of amines can be measured with 10g
of salicylic acid.
Q7
What coulometric titration reagents are there? Please explain the
types of reagents and their uses, and the methods employed.
Mitsubishi Chemical Corporation offers a range of coulometric titration
reagents to suit user requirements. These products can be broadly
categorized into the following four types.
�General-purpose electrolytes (two types)
These are general-purpose reagents for use with normal
samples.
�Ketone electrolyte (one type)
This is used with ketones and lower carboxylic acid, etc.
�Check solution (one type)
This product is used for end point checking.
�Standard liquid (two types)
This reagent is used to check the moisture meters used in
coulometric titration.
Advice to Users
Electrolytes are of two types; anolyte, which is placed in the anode chamber
of the electrolysis cell, and catholyte, which is placed in the cathode
chamber. Both these products form one pair.
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