Development of Karl Fischer Reagents

10. Organic Acid Salts
Key Points
Chapter II: Applications - 1
Since organic acid salts containing water of crystallization dissolve
readily in methanol, their moisture content can be measured easily
using a general-use dehydrated solvent. In the case of organic acid
salts that do not contain water of crystallization, moisture content can
be measured by dissolving or dispersing the substances in a generaluse
dehydrated solvent. As these substances are solids with a high
moisture content, we recommend measurement using volumetric
titration.
The organic salt sodium tartrate dihydrate was formerly sed as a
standard reagent for determining the titer of Karl Fischer reagents for
use in volumetric titration.
Examples of substances that can be measured directly:
Organic acid salts containing water of crystallization
Barium acetate, cadmium acetate, cobalt acetate, lead acetate, magnesium
acetate, nickel acetate, sodium acetate, zinc acetate, uranyl acetate, sodium
citrate, lithium citrate, calcium lactate, calcium malonate, sodium
naphthionate, ammonium oxalate, potassium oxalate, calcium propionate,
sodium succinate, sodium benzoate, sodium tartrate
Organic acid salts without water of crystallization
Ammonium acetate, sodium adipicate, potassium hydrogen tartrate,
ammonium citrate, sodium formate, sodium phthalate, zinc stearate
[Examples of Measurement]
(1) Volumetric titration
Reagents used: Karl Fischer Reagent SS-Z (or SS)
Dehydrated Solvent GEX (or MS) 25-50ml
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