8th Liquid Matter Conference September 6-10, 2011 Wien, Austria ...

P9.70Tue 611:23-14:00Nanoscopic modelling: a fractal concept for protein formand structuresRupert Tscheliessnig 11 ACIB GmbH, Petersgasse 14, 8010, Graz, AustriaFrequently, proteins at surfaces or in solution can be considered as systems close to criticality.We developed a fractal theory suitable to calculate the proteins three dimensional form on anatomistic respectively nanoscopic level on basis of small angle X-Ray scattering and tiltingTransmission Electron Microscopy experiments [1, 2, 3]. The investigated proteins aggregate orassemble in particular structures. The proteins electrostatics and their hydration hull do play keyroles for either of these processes. From the particular proteins structures we deduce a fractalmean potential. We then use this, to calculate particular properties of the investigated systems:i. e. the influence of the protein secondary structure on the hydration hull, the possible reactionpaths towards the formation of aggregates and self assemblies, their rheological (antifouling)characteristics or possible diffusion paths of salts through nanopores.[1] Christine Horejs, Dietmar Pum, Uwe B. Sleytr, Rupert Tscheliessnig J. Chem. Phys.128, 065106 (2008)[2] Christine Horejs, Dietmar Pum, Uwe B. Sleytr, Herwig Peterlik, Alois Jungbauer, and RupertTscheliessnig J. Chem. Phys. 133, 175102 (2010)[3] Christine Horejs, Harald Gollner, Dietmar Pum, Uwe B. Sleytr, Herwig Peterlik, AloisJungbauer, and Rupert Tscheliessnig ACS Nano 5(3), 2288 (2011)70