Guidelines for Complications of Cancer Treatment Vol VIII Part B

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5. Hünerbein M, Hohenberger P, Stroszczynski C, BarteltN, Schlag PM, Tunn PU. Intravascular ultrasonographyduring resection of soft tissue sarcoma Br J Surg. 2007Feb;94(2):168-73.6. Schwarzbach MH, Hormann Y, Hinz U, Bernd L, WillekeF, Mechtersheimer G, Böckler D, Schumacher H,Herfarth C, Büchler MW, Allenberg JR. Results of limbsparingsurgery with vascular replacement for soft tissuesarcoma in the lower extremity. J Vasc Surg. 2005Jul;42(1):88-977. Tsukushi S, Nishida Y, Sugiura H, Nakashima H, IshiguroN. Results of Limb-Salvage Surgery With VascularReconstruction For Soft Tissue Sarcoma in the LowerExtremity: Comparison Between Only Arterial andArterovenous Reconstruction. J Surg Oncol. 2008 Mar1;97(3):216-20.8. Ghert MA, Davis AM, Griffin AM, Alyami AH, WhiteL, Kandel RA, Ferguson P, O’Sullivan B, Catton CN,Lindsay T, Rubin B, Bell RS, Wunder JS. The Surgicaland Functional Outcome of Limb-Salvage Surgery WithVascular Reconstruction for Soft Tissue Sarcoma of theExtremity. Ann Surg Oncol. 2005 Dec;12(12):1102-10.9. McKay A, Motamedi M, Temple W, Mack L, Moore R.Vascular Reconstruction With the Superficial FemoralVein Following Major Oncologic Resection J SurgOncol. 2007 Aug 1;96(2):151-9.149
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Guidelines forComplications ofCance
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Dedicated toAll our patients atThe
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Section IIHead & Neck 151Complicati
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PrefaceTreatment of cancer by vario
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Section — IGeneralContributorsDr.
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6. Complications after breast recon
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promises to reduce this risk of ser
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preceded by increased sensory hyper
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had significant lymphoedema. The fa
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2. Smoking as a risk factor for wou
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4. Preoperative core needle biopsy
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eduction mammoplasty, and axillary-
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postoperative wound infection follo
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ablative surgical treatment for car
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postoperative seroma formation usin
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dressing consisted of a circumferen
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mastectomies with axillary node cle
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mastectomy for breast cancer. Early
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monitored for the development of po
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modality, and tumor stage distribut
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26. Pain and other symptoms during
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28. Coping, catastrophizing and chr
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surgical technique at the time of m
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0.001), 0.315 cm +/- 1.27 at the an
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or heat and superficial incision is
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RecommendationsA. Preparation of th
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3. Mangram AJ, Horan TC, Pearson ML
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Mild hypothermia increases blood lo
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Perioperative Normothermia to Reduc
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Priorities: Restoration of circulat
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than 1.5 times control values but f
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outcomes that may result from the u
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Preoperative Preparation of the Pat
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patients, or other patients who may
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Obstruction can occur at the level
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c. Administer face mask preoxygenat
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5. The use of exhaled carbon dioxid
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disorder) may occur after an episod
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undergoing general anesthesia, eith
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anesthesia awareness occurred in ea
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The current guidelines are actually
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o S - Strong Recommendation -Commit
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oSource control ASAP after successf
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oooWean steroids once vasopressors
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Mechanical ventilation of sepsis-in
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o CVVH offers easier management inh
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critically ill patient that are con
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Rivers E, Nguyen B, Havstad S, et a
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in survival of 7.6%. By the second
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parameters (gastric mucosal Pco2, s
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syndrome. We therefore conducted a
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Complications After Limb SalvageSur
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Page 112 and 113: 4. Griffin AM, Parsons JA, Davis AM
Page 114 and 115: 20. Roberts P, Chan D, Grimer RJ, e
Page 116 and 117: An infection can have disastrous co
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Page 120 and 121: features of a two-stage revision is
Page 122 and 123: patients had an amputation. Two oth
Page 124 and 125: its main role is confined to ruling
Page 126 and 127: 2. Capanna R, Morris HG, Campanacci
Page 128 and 129: 21. Wilson MG, Kelley K, Thornhill
Page 130 and 131: 39. Love C, Marwin SE, Tomas MB, Kr
Page 132 and 133: 5. A systematic review of 25 RCT’
Page 134 and 135: (cefazolin or cefuroxime) or penici
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Page 138 and 139: such as concomitant use of prophyla
Page 140 and 141: Surgical techniqueAdherence to meti
Page 142 and 143: 2. Another small prospective random
Page 144 and 145: Antibiotic prophylaxis for dental a
Page 146 and 147: Antimicrobial Prophylaxis in Orthop
Page 148 and 149: 35. Tai CC, Nirvani AA, Holmes A, e
Page 150 and 151: 53. Parker MJ, Roberts C. Closed su
Page 152 and 153: Vessel Related Issues in Sarcoma:Ev
Page 154 and 155: sequences may be of value. They cau
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Page 160: Section — IIHead and NeckContribu
Page 163 and 164: ManagementPrinciples The most impor
Page 165 and 166: 4. Baker S.R. and Swanson N.A. Reco
Page 167 and 168: Osteoradionecrosis of the MandibleD
Page 169 and 170: Injury or dental extractions: Any s
Page 171 and 172: the patients responded to HBO alone
Page 173 and 174: 9. Lyons A, Ghazali N. Osteoradione
Page 175 and 176: XerostomiaXerostomia is present in
Page 177 and 178: eduction in salivary pH, decreased
Page 179 and 180: 170to those that received placebo.
Page 181 and 182: has been on techniques like IMRT, I
Page 183 and 184: 8. Eisbruch A, Kim HM, Terrell JE,
Page 185 and 186: tonsillar region Int J Radiat Oncol
Page 187 and 188: Deterioration in the Quality of lif
Page 189 and 190: Toxicity gradingGrade 0 Grade 1 Gra
Page 191 and 192: Shown to decrease the severity and
Page 193 and 194: Problems Associated with Free Tissu
Page 195 and 196: - A flap with arterial blockade sho
Page 197 and 198: - Graft loss is commonly due to she
Page 199 and 200: References1. Microvascular free fla
Page 201 and 202: Recurrent Laryngeal Nerve (RLN)a. R
Page 203 and 204: When the EBSLN is damaged unilatera
Page 205 and 206: References1. Hermann M, Alk G, Roka
Page 207 and 208: Hypocalcemia FollowingThyroidectomy
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Prevention Thorough knowledge of th
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Annual Ophthalmologist evaluation f
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Risk factors Poor nutritional statu
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However, more often than not, inser
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Post-Laryngectomy TracheostomalSten
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Previous tracheostomy - no conclusi
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ChondroradionecrosisIntroduction an
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Concomitant chemotherapy may compou
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despite repeated negative biopsies
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Swallowing Dysfunction after Treatm
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Commonest dysfunction on MBS after
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Head rotated to the Improves vocal
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Hypothyroidism After Treatment forH
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References1) Long-term incidence of
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IV - Moderately severe dysfunction
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The functional status of the facial
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Frey’s SyndromeFrey’s syndrome
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The affected area is painted with i
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ReferencesManagement of Frey syndro
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Incidence:Depends upon the type of
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References1. Impact of shoulder com
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After every neck dissection, put th
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Algorithm for management of fistula
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PreventionThe main principle to pre
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difficult to appreciate. Characteri
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Operative Techniques include:1) End
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ooCisplatin, as single agent is the
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oooin many trials though the differ
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creatinine in males, 0.85 X (140-ag
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o Treatment of febrile neutropenia
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6. Seiwert TY, Salama JK and Vokes
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Complications of Abdomino-PelvicRad
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With these doses, the rate of necro
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sigmoid colon and rectum being in c
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complication rate of late rectal to
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after radiation therapy, bladder ir
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partial symptomatic resolution (P =
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increased with concurrent administr
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Suggested Reading:1. Hall EJ. Radio
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Radiation Induced Second MalignantN
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Table I: Risk of subsequent cancer
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traversed by a charged particle but
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modality treatment than RT alone (6
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vulva, anal canal and oropharynx) a
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Registries, 1973-2000. National Can
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Suggested Reading:1. Goldsby R, Bur
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adiation dose, and age at treatment
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dose. The excess relative risk for
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Radiation Induced Cardiac &Pulmonar
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Acute fibrinous pericarditis can pr
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Cardiac Morbidity & MortalityCardio
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effusion a mean of 150 days after t
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3. Mittal S, Berko B, Bavaria J, et
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Carver JR, Shapiro CL, Ng A, Jacobs
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RESULTS: In the total group, the ri
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For women diagnosed during 1993-200
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5.4%, SE 1.3, 2p=0.0002; overall mo
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PneumonitisThe clinical syndrome of
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Measurable end points of Pulmonary
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Useful radiation therapy planning p
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7. Rubin, P. Radiation toxicity: Qu
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profibrotic cytokines and molecules
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Graham MV, Purdy JA, Emami B, Harms
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Radiation MyelopathyIntroduction:Sp
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probably secondary to damage to the
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Time Course of Events: The onset ma
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since previous treatment, although
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tried 36 . Novel therapies as stem
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14. Abramson N, Cavanaugh PJ. Short
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MRI in differentiating spinal cord
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acceptability of the types of treat
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Radiation Induced Central NervousSy
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sensory or motor impairment. Numero
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Randomized trial in craniospinal ra
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RT to brain has been implicated as
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that there will be higher probabili
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Pseudo-progression needs to be diff
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CONCLUSION: The results document a
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Intelligence Score Chart (WISC), wh
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hypothesized ordering of groups in
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PATIENTS AND METHODS: Follow-up stu
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had undergone surgical procedure in
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which mirrors the increased inciden
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with population incidence rates thr
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Section — IVMedical OncologyContr
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Initial investigations - Complete b
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In low risk group, patient may rece
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trial design issues.1 Fluconazole s
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Duration of treatment may depend up
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Antibacterial agents-Overall risk E
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Gram positive DOSE Spectrum Comment
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Broad spectrum DOSE Spectrum Commen
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6. Bow EJ, Rotstein C, Noskin GA, e
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2. Delayed CINV: Nausea and vomitin
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Recommended Treatment OptionsAcute
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Evidence Based Management Guideline
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Management of refractory and breakt
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serotonin antagonist and dexamethas
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(no vomiting and no use of rescue t
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within 24 hours after the start of
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with age, often becoming clinically
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guidelines for screening & manageme
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Level Treatment Method of Frequency
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15. Wallace WH, Blacklay A, Eiser C
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health status domains were assessed
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of childhood cancer survivors is no
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Tumor Lysis SyndromeDefinition: Tum
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the grade of CTLS is defined by the
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Alkalinization for patients who wil
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deficiency should include a thoroug
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icarbonate and calcium should not b
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and should have ready access to ras
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Table 3 Risk Factors for Tumor Lysi
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Table 5 Recommended Rasburicase Dos
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1. Guidelines for the management of
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3. A randomized comparison between
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acid levels (6.4-16.8 mg/dl; median
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adiographic pattern is the hilar ly
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study involving 105 patients was 8.
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10. Sostman HD, Matthay RA, Putman
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distinguish between a normal GFR an
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of methotrexate induced nephropathy
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Bibliography1. De Jonge MJ, Verweij
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Mucositis and GastrointestinalToxic
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pathogenesis is similar for gastroi
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acceptable oral protocol include re
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Treatment of gastrointestinal mucos
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Hepatotoxicity ofChemotherapeutic A
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Capecitabine is the prodrug for 5-F
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Topotecan causes elevation of trans
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Daunorubicin: Reduce dose by 25% if
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9. Spriggs DR, Stopa E, Mayer RJ, e
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Dermatologic Toxicity of Antineopla
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ecause 15% of scalp hairs are not i
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5. Batchelor D. Hair and cancer che
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Anemia and Cancer - incidence, etio
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most accurate method for detecting
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levels, to define anemia and this m
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Darbopoietin Vs Epoetin Alfa: Is Th
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arm (2.4 g/dl) compared to patients
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12. Yellen SB, Cella DF, Webster K,
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490NOTES
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NOTES
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