Guidelines for Complications of Cancer Treatment Vol VIII Part B

oDo not use antithrombin therapy (1B)2004 BTransfuse plateletso when counts < 5000/mm 3 , regardless of bleeding(2D) Wo With counts 5000–30,000/mm 3 with significantbleeding risko Higher platelet counts (50,000/mm 3 ) for surgeryor invasive procedures 2004 B, E, EMechanical ventilation of sepsis-induced ALI/ARDSSeta Target V Tof 6 mL/kg (predicted) in patients with ALI/ARDS (1B) So Target an initial upper limit plateau pressure < 30cm H 2O. Consider chest wall compliance whenassessing plateau pressure. (1C) So Allow PaCO 2to increase above normal, if needed,to minimize plateau pressures and tidal volumes(1C) So Set PEEP to avoid extensive lung collapse at endexpiration(1C) S 2004 B, C, EooConsider using the prone position for ARDSpatients requiring potentially injurious levels ofFiO 2or plateau pressure, provided they are not putat risk from positional changes (2C) WMaintain mechanically ventilated patients in asemirecumbent position (head of the bed raised to45°) unless contraindicated (1B) S, between 30°and 45° (2C) W 2004 E, C82