Guidelines for Complications of Cancer Treatment Vol VIII Part B

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Section — IIHead and NeckContributorsQ Ahmed, Mch (Plastic Surgery)A Buddrukar, DNB, MD, DMRTD Chaukar, MS, DNBP Chaturvedi, MS, DNBA D’Cruz, MS, DNBM Deshpande, MS, DNBR Gaikwad, MSS G Laskar, DNB, MD, DMRTA Moiyadi, MCh (Neurosurgery)V Murthy, DNB, MDP Pai, MS, DNBG Pantvaidya, MS, DNBM Sengar, DMV Shankdhar, MS, Mch (Plastic Surgery)P Shetty, Mch (Neurosurgery)P Yadav, MS (Plastic Surgery)
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Guidelines forComplications ofCance
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Dedicated toAll our patients atThe
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Section IIHead & Neck 151Complicati
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PrefaceTreatment of cancer by vario
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Section — IGeneralContributorsDr.
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6. Complications after breast recon
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promises to reduce this risk of ser
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preceded by increased sensory hyper
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had significant lymphoedema. The fa
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2. Smoking as a risk factor for wou
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4. Preoperative core needle biopsy
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eduction mammoplasty, and axillary-
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postoperative wound infection follo
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ablative surgical treatment for car
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postoperative seroma formation usin
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dressing consisted of a circumferen
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mastectomies with axillary node cle
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mastectomy for breast cancer. Early
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monitored for the development of po
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modality, and tumor stage distribut
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26. Pain and other symptoms during
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28. Coping, catastrophizing and chr
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surgical technique at the time of m
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0.001), 0.315 cm +/- 1.27 at the an
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or heat and superficial incision is
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RecommendationsA. Preparation of th
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3. Mangram AJ, Horan TC, Pearson ML
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Mild hypothermia increases blood lo
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Perioperative Normothermia to Reduc
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Priorities: Restoration of circulat
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than 1.5 times control values but f
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outcomes that may result from the u
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Preoperative Preparation of the Pat
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patients, or other patients who may
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Obstruction can occur at the level
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c. Administer face mask preoxygenat
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5. The use of exhaled carbon dioxid
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disorder) may occur after an episod
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undergoing general anesthesia, eith
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anesthesia awareness occurred in ea
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The current guidelines are actually
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o S - Strong Recommendation -Commit
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oSource control ASAP after successf
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oooWean steroids once vasopressors
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Mechanical ventilation of sepsis-in
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o CVVH offers easier management inh
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critically ill patient that are con
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Rivers E, Nguyen B, Havstad S, et a
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in survival of 7.6%. By the second
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parameters (gastric mucosal Pco2, s
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syndrome. We therefore conducted a
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Complications After Limb SalvageSur
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Page 120 and 121: features of a two-stage revision is
Page 122 and 123: patients had an amputation. Two oth
Page 124 and 125: its main role is confined to ruling
Page 126 and 127: 2. Capanna R, Morris HG, Campanacci
Page 128 and 129: 21. Wilson MG, Kelley K, Thornhill
Page 130 and 131: 39. Love C, Marwin SE, Tomas MB, Kr
Page 132 and 133: 5. A systematic review of 25 RCT’
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Page 138 and 139: such as concomitant use of prophyla
Page 140 and 141: Surgical techniqueAdherence to meti
Page 142 and 143: 2. Another small prospective random
Page 144 and 145: Antibiotic prophylaxis for dental a
Page 146 and 147: Antimicrobial Prophylaxis in Orthop
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Page 150 and 151: 53. Parker MJ, Roberts C. Closed su
Page 152 and 153: Vessel Related Issues in Sarcoma:Ev
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Page 163 and 164: ManagementPrinciples The most impor
Page 165 and 166: 4. Baker S.R. and Swanson N.A. Reco
Page 167 and 168: Osteoradionecrosis of the MandibleD
Page 169 and 170: Injury or dental extractions: Any s
Page 171 and 172: the patients responded to HBO alone
Page 173 and 174: 9. Lyons A, Ghazali N. Osteoradione
Page 175 and 176: XerostomiaXerostomia is present in
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Page 181 and 182: has been on techniques like IMRT, I
Page 183 and 184: 8. Eisbruch A, Kim HM, Terrell JE,
Page 185 and 186: tonsillar region Int J Radiat Oncol
Page 187 and 188: Deterioration in the Quality of lif
Page 189 and 190: Toxicity gradingGrade 0 Grade 1 Gra
Page 191 and 192: Shown to decrease the severity and
Page 193 and 194: Problems Associated with Free Tissu
Page 195 and 196: - A flap with arterial blockade sho
Page 197 and 198: - Graft loss is commonly due to she
Page 199 and 200: References1. Microvascular free fla
Page 201 and 202: Recurrent Laryngeal Nerve (RLN)a. R
Page 203 and 204: When the EBSLN is damaged unilatera
Page 205 and 206: References1. Hermann M, Alk G, Roka
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Prevention Thorough knowledge of th
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Annual Ophthalmologist evaluation f
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Risk factors Poor nutritional statu
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However, more often than not, inser
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Post-Laryngectomy TracheostomalSten
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Previous tracheostomy - no conclusi
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ChondroradionecrosisIntroduction an
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Concomitant chemotherapy may compou
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despite repeated negative biopsies
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Swallowing Dysfunction after Treatm
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Commonest dysfunction on MBS after
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Head rotated to the Improves vocal
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Hypothyroidism After Treatment forH
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References1) Long-term incidence of
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IV - Moderately severe dysfunction
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The functional status of the facial
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Frey’s SyndromeFrey’s syndrome
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The affected area is painted with i
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ReferencesManagement of Frey syndro
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Incidence:Depends upon the type of
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References1. Impact of shoulder com
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After every neck dissection, put th
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Algorithm for management of fistula
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PreventionThe main principle to pre
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difficult to appreciate. Characteri
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Operative Techniques include:1) End
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ooCisplatin, as single agent is the
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oooin many trials though the differ
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creatinine in males, 0.85 X (140-ag
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o Treatment of febrile neutropenia
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6. Seiwert TY, Salama JK and Vokes
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Complications of Abdomino-PelvicRad
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With these doses, the rate of necro
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sigmoid colon and rectum being in c
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complication rate of late rectal to
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after radiation therapy, bladder ir
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partial symptomatic resolution (P =
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increased with concurrent administr
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Suggested Reading:1. Hall EJ. Radio
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Radiation Induced Second MalignantN
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Table I: Risk of subsequent cancer
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traversed by a charged particle but
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modality treatment than RT alone (6
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vulva, anal canal and oropharynx) a
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Registries, 1973-2000. National Can
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Suggested Reading:1. Goldsby R, Bur
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adiation dose, and age at treatment
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dose. The excess relative risk for
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Radiation Induced Cardiac &Pulmonar
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Acute fibrinous pericarditis can pr
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Cardiac Morbidity & MortalityCardio
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effusion a mean of 150 days after t
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3. Mittal S, Berko B, Bavaria J, et
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Carver JR, Shapiro CL, Ng A, Jacobs
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RESULTS: In the total group, the ri
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For women diagnosed during 1993-200
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5.4%, SE 1.3, 2p=0.0002; overall mo
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PneumonitisThe clinical syndrome of
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Measurable end points of Pulmonary
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Useful radiation therapy planning p
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7. Rubin, P. Radiation toxicity: Qu
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profibrotic cytokines and molecules
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Graham MV, Purdy JA, Emami B, Harms
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Radiation MyelopathyIntroduction:Sp
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probably secondary to damage to the
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Time Course of Events: The onset ma
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since previous treatment, although
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tried 36 . Novel therapies as stem
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14. Abramson N, Cavanaugh PJ. Short
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MRI in differentiating spinal cord
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acceptability of the types of treat
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Radiation Induced Central NervousSy
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sensory or motor impairment. Numero
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Randomized trial in craniospinal ra
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RT to brain has been implicated as
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that there will be higher probabili
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Pseudo-progression needs to be diff
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CONCLUSION: The results document a
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Intelligence Score Chart (WISC), wh
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hypothesized ordering of groups in
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PATIENTS AND METHODS: Follow-up stu
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had undergone surgical procedure in
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which mirrors the increased inciden
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with population incidence rates thr
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Section — IVMedical OncologyContr
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Initial investigations - Complete b
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In low risk group, patient may rece
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trial design issues.1 Fluconazole s
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Duration of treatment may depend up
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Antibacterial agents-Overall risk E
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Gram positive DOSE Spectrum Comment
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Broad spectrum DOSE Spectrum Commen
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6. Bow EJ, Rotstein C, Noskin GA, e
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2. Delayed CINV: Nausea and vomitin
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Recommended Treatment OptionsAcute
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Evidence Based Management Guideline
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Management of refractory and breakt
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serotonin antagonist and dexamethas
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(no vomiting and no use of rescue t
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within 24 hours after the start of
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with age, often becoming clinically
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guidelines for screening & manageme
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Level Treatment Method of Frequency
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15. Wallace WH, Blacklay A, Eiser C
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health status domains were assessed
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of childhood cancer survivors is no
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Tumor Lysis SyndromeDefinition: Tum
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the grade of CTLS is defined by the
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Alkalinization for patients who wil
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deficiency should include a thoroug
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icarbonate and calcium should not b
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and should have ready access to ras
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Table 3 Risk Factors for Tumor Lysi
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Table 5 Recommended Rasburicase Dos
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1. Guidelines for the management of
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3. A randomized comparison between
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acid levels (6.4-16.8 mg/dl; median
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adiographic pattern is the hilar ly
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study involving 105 patients was 8.
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10. Sostman HD, Matthay RA, Putman
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distinguish between a normal GFR an
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of methotrexate induced nephropathy
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Bibliography1. De Jonge MJ, Verweij
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Mucositis and GastrointestinalToxic
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pathogenesis is similar for gastroi
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acceptable oral protocol include re
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Treatment of gastrointestinal mucos
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Hepatotoxicity ofChemotherapeutic A
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Capecitabine is the prodrug for 5-F
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Topotecan causes elevation of trans
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Daunorubicin: Reduce dose by 25% if
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9. Spriggs DR, Stopa E, Mayer RJ, e
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Dermatologic Toxicity of Antineopla
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ecause 15% of scalp hairs are not i
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5. Batchelor D. Hair and cancer che
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Anemia and Cancer - incidence, etio
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most accurate method for detecting
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levels, to define anemia and this m
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Darbopoietin Vs Epoetin Alfa: Is Th
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arm (2.4 g/dl) compared to patients
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12. Yellen SB, Cella DF, Webster K,
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490NOTES
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NOTES
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Guidelines for Complications of Cancer Treatment Vol VIII Part B

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