Guidelines for Complications of Cancer Treatment Vol VIII Part B

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Section — IVMedical OncologyContributorsDr. S D Banavali, MD, INT. MED. MD. (PAED),BE (PAED) HEAM ONCODr. P A Kurkure, MD, DCHDr. Reena Nair, MDDr. Sudeep Gupta, MD, DMDr. Brijesh Arora, MD, DMDr. Kumar Prabhash, MD, DMDr. Hari Menon, MD, DMDr. Manju Sengar, MD, DMDr. Navin Khatry, MD, DMDr. Amit Joshi, MD, DMDr. Urvinder Kaur, DNB, DCHDr. Seema Gulia, MDDr. Amol Akhade, MDDr. Randeep Singh, MDDr. Vandana Dhamankar, MDDr. Mithun Shah, MD, DMDr. Nandish Kumar, MDDr. Nirmal Raut, MD
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Guidelines forComplications ofCance
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Dedicated toAll our patients atThe
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Section IIHead & Neck 151Complicati
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PrefaceTreatment of cancer by vario
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Section — IGeneralContributorsDr.
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6. Complications after breast recon
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promises to reduce this risk of ser
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preceded by increased sensory hyper
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had significant lymphoedema. The fa
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2. Smoking as a risk factor for wou
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4. Preoperative core needle biopsy
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eduction mammoplasty, and axillary-
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postoperative wound infection follo
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ablative surgical treatment for car
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postoperative seroma formation usin
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dressing consisted of a circumferen
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mastectomies with axillary node cle
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mastectomy for breast cancer. Early
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monitored for the development of po
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modality, and tumor stage distribut
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26. Pain and other symptoms during
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28. Coping, catastrophizing and chr
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surgical technique at the time of m
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0.001), 0.315 cm +/- 1.27 at the an
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or heat and superficial incision is
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RecommendationsA. Preparation of th
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3. Mangram AJ, Horan TC, Pearson ML
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Mild hypothermia increases blood lo
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Perioperative Normothermia to Reduc
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Priorities: Restoration of circulat
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than 1.5 times control values but f
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outcomes that may result from the u
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Preoperative Preparation of the Pat
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patients, or other patients who may
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Obstruction can occur at the level
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c. Administer face mask preoxygenat
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5. The use of exhaled carbon dioxid
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disorder) may occur after an episod
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undergoing general anesthesia, eith
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anesthesia awareness occurred in ea
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The current guidelines are actually
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o S - Strong Recommendation -Commit
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oSource control ASAP after successf
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oooWean steroids once vasopressors
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Mechanical ventilation of sepsis-in
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o CVVH offers easier management inh
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critically ill patient that are con
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Rivers E, Nguyen B, Havstad S, et a
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in survival of 7.6%. By the second
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parameters (gastric mucosal Pco2, s
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syndrome. We therefore conducted a
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Complications After Limb SalvageSur
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local tumor and to preserve as much
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femoral head to the center of the k
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4. Griffin AM, Parsons JA, Davis AM
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20. Roberts P, Chan D, Grimer RJ, e
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An infection can have disastrous co
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and facilitating reimplantation sur
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features of a two-stage revision is
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patients had an amputation. Two oth
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its main role is confined to ruling
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2. Capanna R, Morris HG, Campanacci
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21. Wilson MG, Kelley K, Thornhill
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39. Love C, Marwin SE, Tomas MB, Kr
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5. A systematic review of 25 RCT’
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(cefazolin or cefuroxime) or penici
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should be based on the isolates fro
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such as concomitant use of prophyla
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Surgical techniqueAdherence to meti
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2. Another small prospective random
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Antibiotic prophylaxis for dental a
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Antimicrobial Prophylaxis in Orthop
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35. Tai CC, Nirvani AA, Holmes A, e
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53. Parker MJ, Roberts C. Closed su
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Vessel Related Issues in Sarcoma:Ev
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sequences may be of value. They cau
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an excellent alternative to amputat
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5. Hünerbein M, Hohenberger P, Str
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Oral IncompetenceOral competence is
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flap is insensate and has no motor
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16. R. Song, Y. Gao, Y. Song, Y. Yu
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The incidence is usually lower afte
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Late fibrotic phase: Attempted tiss
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Ref: A Lyons, N Ghazali/ British J
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17. Store G, Boysen M. Mandibular o
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amino acids, proteins and traces of
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RTOG, EORTC and CTCAE, version 3 fo
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difference in the disease related p
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References1. Bourhis J, Rosine D. R
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with head and neck cancer. N Engl J
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MucositisMucositis is an inflammato
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Type of cancer: high risk for mucos
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Oral care protocol1. Brush all toot
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3. El-Sayed S, Nabid A, ShelleyW, e
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1) Recipient site problems- The maj
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estoration of vascular flow to tiss
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General Complications- Deep vein th
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Nerve Injuries(Recurrent and Superi
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paramedian position, it will result
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along with its variations, and a me
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anatomy as related to surgery of th
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Risk factorsCentral compartment (Le
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Goal - To raise serum calcium level
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Pharyngocutaneous Fistula (PC Fistu
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Based on our institutional practice
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fistula: The Memorial University ex
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Risk factors (LOE-5)Patient factors
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oCircumferencial excision and inser
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y trauma or tumor, exposing the und
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Arytenoid cartilage is reported to
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Filntisis, G.A., et al. “Laryngea
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As high as 52% patients are detecte
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ManagementPostural exercisesDisorde
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References1) Objective assessment o
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Diagnosis Average time to hypothyro
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Management of Facial Nerve InjuryIn
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2. Interposition or cable graft (to
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Prevention of corneal exposure Tars
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flushing) and localized sweating (g
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Other options :1. Intracutaneous in
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Shoulder Dysfunction or PainfulShou
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EMG studies on scapulo-humeral and
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Chyle Fistula after Neck Dissection
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Rationale:LCTs, which constitute 70
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CSF Leak after Craniofacial Resecti
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to the muscle to recreate the orbit
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Conservative treatmentIt is logical
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Complications Associated with use o
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Following is the example of hematol
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ooooooo direct interaction with the
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ooooointravenously over 15 minutes
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in most of the patients. The common
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Section — IIIRadiotherapyContribu
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nodes are involved or suspected to
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function. In general, with conventi
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like ultrasonography, CT scan, endo
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catheter passed through the anus in
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Acute symptoms usually subside seve
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granulocytopenia, thrombocytopenia
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adiation therapy), IMRT (intensity-
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patients who have received radical
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ate expected in the standard popula
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adjusting for competing causes of d
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therapy (3D-CRT) and intensity modu
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attributed to use of cisplatin base
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Conclusion:Incidence of SMN is incr
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11. Travis LB, Fossa SD, Schonfeld
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adiation-related solid SMNs will in
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0.71, p
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5.65%) within 45 years after a CNS
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adiation damage though supporting v
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without calcification. Inflammation
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patients treated using the original
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incidence of valvular thickening at
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12. Hancock S, Hoppe R. Long-term c
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syndrome and bronchiolitis oblitera
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Darby SC, McGale P, Taylor CW, Peto
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undertaken, based on individual pat
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Pathophysiological Aspects:The func
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Symptoms: Symptoms related to pulmo
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Page 336 and 337: Int J Radiat Oncol Biol Phys. 1995
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Page 340 and 341: Differential Diagnosis: This sign i
Page 342 and 343: Dose Incidence Comments Author>30 G
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Page 346 and 347: 3. Pallis CA, Louis S, Morgan RL.:
Page 348 and 349: 24. Abbatucci JS, Delozier T, Quint
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Page 354 and 355: Complications are mainly described
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Page 360 and 361: development after brain tumor thera
Page 362 and 363: Highest relative risk of second can
Page 364 and 365: Suggested Reading:A) Neuropsycholog
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Page 368 and 369: number of patients. Cognition was p
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Page 372 and 373: 15 of 20 (75%) subjects, endocrine
Page 374 and 375: OBJECTIVE: To assess cerebrovascula
Page 376 and 377: hypometabolism. Of the 17 patients
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Page 383 and 384: Initial investigations - Complete b
Page 385 and 386: In low risk group, patient may rece
Page 387 and 388: trial design issues.1 Fluconazole s
Page 389 and 390: Duration of treatment may depend up
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Page 393 and 394: Gram positive DOSE Spectrum Comment
Page 395 and 396: Broad spectrum DOSE Spectrum Commen
Page 401 and 402: 6. Bow EJ, Rotstein C, Noskin GA, e
Page 403 and 404: 2. Delayed CINV: Nausea and vomitin
Page 405 and 406: Recommended Treatment OptionsAcute
Page 407 and 408: Evidence Based Management Guideline
Page 409 and 410: Management of refractory and breakt
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Page 421 and 422: Level Treatment Method of Frequency
Page 423 and 424: 15. Wallace WH, Blacklay A, Eiser C
Page 425 and 426: health status domains were assessed
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Tumor Lysis SyndromeDefinition: Tum
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the grade of CTLS is defined by the
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Alkalinization for patients who wil
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deficiency should include a thoroug
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icarbonate and calcium should not b
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and should have ready access to ras
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Table 3 Risk Factors for Tumor Lysi
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Table 5 Recommended Rasburicase Dos
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1. Guidelines for the management of
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3. A randomized comparison between
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acid levels (6.4-16.8 mg/dl; median
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adiographic pattern is the hilar ly
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study involving 105 patients was 8.
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10. Sostman HD, Matthay RA, Putman
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distinguish between a normal GFR an
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of methotrexate induced nephropathy
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Bibliography1. De Jonge MJ, Verweij
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Mucositis and GastrointestinalToxic
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pathogenesis is similar for gastroi
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acceptable oral protocol include re
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Treatment of gastrointestinal mucos
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Hepatotoxicity ofChemotherapeutic A
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Capecitabine is the prodrug for 5-F
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Topotecan causes elevation of trans
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Daunorubicin: Reduce dose by 25% if
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9. Spriggs DR, Stopa E, Mayer RJ, e
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Dermatologic Toxicity of Antineopla
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ecause 15% of scalp hairs are not i
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5. Batchelor D. Hair and cancer che
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Anemia and Cancer - incidence, etio
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most accurate method for detecting
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levels, to define anemia and this m
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Darbopoietin Vs Epoetin Alfa: Is Th
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arm (2.4 g/dl) compared to patients
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12. Yellen SB, Cella DF, Webster K,
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490NOTES
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NOTES
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Guidelines for Complications of Cancer Treatment Vol VIII Part B

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