Guidelines for Complications of Cancer Treatment Vol VIII Part B

1. Purulent drainage from a drain that is placed through astab wound into the organ/space.2. Organisms isolated from an aseptically obtained cultureof fluid or tissue in the organ/space.3. An abscess or other evidence of infection involving theorgan/space that is found on direct examination, duringreoperation, or by histopathologic or radiologicexamination.4. Diagnosis of an organ/space SSI by a surgeon orattending physician.Microbiology of SSIIn clean surgical procedures, Staphylococcus aureus from theexogenous environment or the patient’s skin flora is the usualcause of infection. In clean-contaminated, contaminated, anddirty, the polymicrobial aerobic and anaerobic flora closelyresembling the normal endogenous microflora of the surgicallyresected organ is the most frequently isolated pathogens. 2Guidelines for prevention of SSI 3Rankings of CDC recommendationsCategory 1A: Strongly recommended for implementation andsupported by well-designed experimental, clinical, orepidemiologic studiesCategory 1B: Strongly recommended for implementation andsupported by some experimental, clinical, or epidemiologicstudies and strong theoretical rationaleCategory II: Suggested for implementation and supported bysuggestive clinical or epidemiologic studies or theoreticalrationaleNo recommendation: Practices for which insufficient evidenceor no consensus regarding efficacy exists.43