Guidelines for Complications of Cancer Treatment Vol VIII Part B

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Table I: Risk <strong>of</strong> subsequent cancer after any initial cancer by age at initial diagnosisTotal Males FemalesAge at Initial diagnosis 0 0/E EAR 0 0/E EAR 0 0/E EARAll ages 185,407 1.14* 21 100,428 1.11* 22 84,979 1.17* 2100-17 351 6.13* 15 176 6.44* 15 175 5.84 1518-29 1,401 2.92* 22 562 3.39* 22 839 2.67* 2330-39 4,909 2.37* 39 1,530 2.88* 40 3,379 2.20* 3840-49 13,537 1.16* 39 4,466 1.83* 52 9,071 1.52* 3450-59 34,159 1.27* 32 15,957 1.33* 46 18,202 1.21* 2460-69 62,286 1.13* 23 35,986 1.11* 25 26,300 1.14* 2270-79 52,321 1.02* 4 32,419 1.00* 0 19,902 1.05* 980-115 16,443 0.92* -19 9,332 0.92* -26 7,111 0.93* -14281
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Guidelines forComplications ofCance
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Dedicated toAll our patients atThe
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Section IIHead & Neck 151Complicati
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PrefaceTreatment of cancer by vario
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Section — IGeneralContributorsDr.
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6. Complications after breast recon
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promises to reduce this risk of ser
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preceded by increased sensory hyper
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had significant lymphoedema. The fa
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2. Smoking as a risk factor for wou
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4. Preoperative core needle biopsy
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eduction mammoplasty, and axillary-
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postoperative wound infection follo
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ablative surgical treatment for car
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postoperative seroma formation usin
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dressing consisted of a circumferen
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mastectomies with axillary node cle
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mastectomy for breast cancer. Early
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monitored for the development of po
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modality, and tumor stage distribut
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26. Pain and other symptoms during
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28. Coping, catastrophizing and chr
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surgical technique at the time of m
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0.001), 0.315 cm +/- 1.27 at the an
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or heat and superficial incision is
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RecommendationsA. Preparation of th
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3. Mangram AJ, Horan TC, Pearson ML
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Mild hypothermia increases blood lo
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Perioperative Normothermia to Reduc
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Priorities: Restoration of circulat
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than 1.5 times control values but f
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outcomes that may result from the u
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Preoperative Preparation of the Pat
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patients, or other patients who may
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Obstruction can occur at the level
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c. Administer face mask preoxygenat
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5. The use of exhaled carbon dioxid
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disorder) may occur after an episod
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undergoing general anesthesia, eith
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anesthesia awareness occurred in ea
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The current guidelines are actually
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o S - Strong Recommendation -Commit
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oSource control ASAP after successf
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oooWean steroids once vasopressors
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Mechanical ventilation of sepsis-in
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o CVVH offers easier management inh
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critically ill patient that are con
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Rivers E, Nguyen B, Havstad S, et a
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in survival of 7.6%. By the second
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parameters (gastric mucosal Pco2, s
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syndrome. We therefore conducted a
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Complications After Limb SalvageSur
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local tumor and to preserve as much
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femoral head to the center of the k
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4. Griffin AM, Parsons JA, Davis AM
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20. Roberts P, Chan D, Grimer RJ, e
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An infection can have disastrous co
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and facilitating reimplantation sur
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features of a two-stage revision is
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patients had an amputation. Two oth
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its main role is confined to ruling
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2. Capanna R, Morris HG, Campanacci
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21. Wilson MG, Kelley K, Thornhill
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39. Love C, Marwin SE, Tomas MB, Kr
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5. A systematic review of 25 RCT’
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(cefazolin or cefuroxime) or penici
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should be based on the isolates fro
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such as concomitant use of prophyla
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Surgical techniqueAdherence to meti
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2. Another small prospective random
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Antibiotic prophylaxis for dental a
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Antimicrobial Prophylaxis in Orthop
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35. Tai CC, Nirvani AA, Holmes A, e
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53. Parker MJ, Roberts C. Closed su
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Vessel Related Issues in Sarcoma:Ev
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sequences may be of value. They cau
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an excellent alternative to amputat
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5. Hünerbein M, Hohenberger P, Str
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Oral IncompetenceOral competence is
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flap is insensate and has no motor
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16. R. Song, Y. Gao, Y. Song, Y. Yu
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The incidence is usually lower afte
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Late fibrotic phase: Attempted tiss
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Ref: A Lyons, N Ghazali/ British J
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17. Store G, Boysen M. Mandibular o
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amino acids, proteins and traces of
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RTOG, EORTC and CTCAE, version 3 fo
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difference in the disease related p
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References1. Bourhis J, Rosine D. R
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with head and neck cancer. N Engl J
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MucositisMucositis is an inflammato
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Type of cancer: high risk for mucos
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Oral care protocol1. Brush all toot
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3. El-Sayed S, Nabid A, ShelleyW, e
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1) Recipient site problems- The maj
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estoration of vascular flow to tiss
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General Complications- Deep vein th
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Nerve Injuries(Recurrent and Superi
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paramedian position, it will result
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along with its variations, and a me
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anatomy as related to surgery of th
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Risk factorsCentral compartment (Le
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Goal - To raise serum calcium level
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Pharyngocutaneous Fistula (PC Fistu
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Based on our institutional practice
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fistula: The Memorial University ex
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Risk factors (LOE-5)Patient factors
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oCircumferencial excision and inser
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y trauma or tumor, exposing the und
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Arytenoid cartilage is reported to
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Filntisis, G.A., et al. “Laryngea
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As high as 52% patients are detecte
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ManagementPostural exercisesDisorde
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References1) Objective assessment o
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Diagnosis Average time to hypothyro
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Management of Facial Nerve InjuryIn
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2. Interposition or cable graft (to
Page 240 and 241: Prevention of corneal exposure Tars
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Page 244 and 245: Other options :1. Intracutaneous in
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Page 248 and 249: EMG studies on scapulo-humeral and
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Page 252 and 253: Rationale:LCTs, which constitute 70
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Page 258 and 259: Conservative treatmentIt is logical
Page 260 and 261: Complications Associated with use o
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Page 270: Section — IIIRadiotherapyContribu
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Page 275 and 276: function. In general, with conventi
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Page 281 and 282: Acute symptoms usually subside seve
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Page 289: ate expected in the standard popula
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Page 295 and 296: modality treatment than RT alone (6
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Page 299 and 300: Registries, 1973-2000. National Can
Page 301 and 302: Suggested Reading:1. Goldsby R, Bur
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Page 305 and 306: dose. The excess relative risk for
Page 307 and 308: Radiation Induced Cardiac &Pulmonar
Page 309 and 310: Acute fibrinous pericarditis can pr
Page 311 and 312: Cardiac Morbidity & MortalityCardio
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Page 315 and 316: 3. Mittal S, Berko B, Bavaria J, et
Page 317 and 318: Carver JR, Shapiro CL, Ng A, Jacobs
Page 319 and 320: RESULTS: In the total group, the ri
Page 321 and 322: For women diagnosed during 1993-200
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Page 325 and 326: PneumonitisThe clinical syndrome of
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Page 329 and 330: Useful radiation therapy planning p
Page 331 and 332: 7. Rubin, P. Radiation toxicity: Qu
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Page 335 and 336: Graham MV, Purdy JA, Emami B, Harms
Page 337 and 338: Radiation MyelopathyIntroduction:Sp
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Time Course of Events: The onset ma
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since previous treatment, although
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tried 36 . Novel therapies as stem
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14. Abramson N, Cavanaugh PJ. Short
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MRI in differentiating spinal cord
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acceptability of the types of treat
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Radiation Induced Central NervousSy
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sensory or motor impairment. Numero
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Randomized trial in craniospinal ra
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RT to brain has been implicated as
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that there will be higher probabili
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Pseudo-progression needs to be diff
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CONCLUSION: The results document a
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Intelligence Score Chart (WISC), wh
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hypothesized ordering of groups in
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PATIENTS AND METHODS: Follow-up stu
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had undergone surgical procedure in
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which mirrors the increased inciden
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with population incidence rates thr
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Section — IVMedical OncologyContr
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Initial investigations - Complete b
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In low risk group, patient may rece
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trial design issues.1 Fluconazole s
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Duration of treatment may depend up
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Antibacterial agents-Overall risk E
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Gram positive DOSE Spectrum Comment
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Broad spectrum DOSE Spectrum Commen
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6. Bow EJ, Rotstein C, Noskin GA, e
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2. Delayed CINV: Nausea and vomitin
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Recommended Treatment OptionsAcute
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Evidence Based Management Guideline
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Management of refractory and breakt
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serotonin antagonist and dexamethas
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(no vomiting and no use of rescue t
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within 24 hours after the start of
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with age, often becoming clinically
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guidelines for screening & manageme
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Level Treatment Method of Frequency
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15. Wallace WH, Blacklay A, Eiser C
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health status domains were assessed
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of childhood cancer survivors is no
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Tumor Lysis SyndromeDefinition: Tum
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the grade of CTLS is defined by the
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Alkalinization for patients who wil
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deficiency should include a thoroug
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icarbonate and calcium should not b
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and should have ready access to ras
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Table 3 Risk Factors for Tumor Lysi
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Table 5 Recommended Rasburicase Dos
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1. Guidelines for the management of
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3. A randomized comparison between
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acid levels (6.4-16.8 mg/dl; median
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adiographic pattern is the hilar ly
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study involving 105 patients was 8.
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10. Sostman HD, Matthay RA, Putman
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distinguish between a normal GFR an
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of methotrexate induced nephropathy
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Bibliography1. De Jonge MJ, Verweij
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Mucositis and GastrointestinalToxic
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pathogenesis is similar for gastroi
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acceptable oral protocol include re
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Treatment of gastrointestinal mucos
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Hepatotoxicity ofChemotherapeutic A
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Capecitabine is the prodrug for 5-F
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Topotecan causes elevation of trans
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Daunorubicin: Reduce dose by 25% if
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9. Spriggs DR, Stopa E, Mayer RJ, e
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Dermatologic Toxicity of Antineopla
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ecause 15% of scalp hairs are not i
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5. Batchelor D. Hair and cancer che
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Anemia and Cancer - incidence, etio
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most accurate method for detecting
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levels, to define anemia and this m
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Darbopoietin Vs Epoetin Alfa: Is Th
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arm (2.4 g/dl) compared to patients
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12. Yellen SB, Cella DF, Webster K,
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490NOTES
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NOTES
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Guidelines for Complications of Cancer Treatment Vol VIII Part B

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