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Guidelines for Complications of Cancer Treatment Vol VIII Part B

Guidelines for Complications of Cancer Treatment Vol VIII Part B

Guidelines for Complications of Cancer Treatment Vol VIII Part B

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preceded by increased sensory hyperesthesia in 20-30% cases[26,27]. Most <strong>of</strong> this pain may reduce over a period <strong>of</strong> timebut a chronic pain still persists <strong>for</strong> long periods with waxingand waning by external stimulation [28]. This pain isconsiderably significant in younger women, larger tumors,post-radiation and chemotherapy, and in women with poorcoping skills. In fact, antidepressants are sometimes prescribedto manage such neuropathic pain [29].Damage to the lateral thoracic nerve to serratus anterior canresult in permanent de<strong>for</strong>mity <strong>of</strong> ‘winging <strong>of</strong> the scapula’ andintractable pain. Care should be taken not to venture too closeto the nerve during axillary dissection especially while usingan electrocautery <strong>for</strong> dissection. Transection <strong>of</strong> the medial andlateral pectoral nerves can permanently denervate the pectoralismuscle and cause cosmetic and functional disability.Saving the intercostobrachial nerve was considered as a way<strong>of</strong> reducing postoperative neuropathic pain. Un<strong>for</strong>tunately, thismay not be so as traction on the nerve or partial nerve damage(neuropraxia) eventually results in more intractableneuropathic pain and distress.Proper Incision PlanningProper placement <strong>of</strong> incisions in both breast conservationsurgery and at the time <strong>of</strong> mastectomy goes a long way inimproving quality <strong>of</strong> life <strong>of</strong> the woman. At the time <strong>of</strong>lumpectomy, incisions in upper half <strong>of</strong> the breast should becircumferentially planned while in the lower half, radialincisions are preferred <strong>for</strong> better cosmetic outcome. In casean excision <strong>of</strong> skin ellipse is necessary, a radial incision isbetter to avoid nipple deviations and poor cosmetic outcome.An important precaution to be remembered at the time <strong>of</strong>mastectomy incisions is to not allow the lateral most point <strong>of</strong>incision to cross the anterior axillary line and to use a teardropor pear-shaped incision with point on medial aspect and8

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